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SRX4157936: GSM3172972: input_3586; Escherichia coli; ChIP-Seq
1 ION_TORRENT (Ion S5) run: 7.9M spots, 1.4G bases, 781.5Mb downloads

Submitted by: NCBI (GEO)
Study: Genome-wide maps of ParBF (SopB) binding on plasmid F or E.coli chromosome carrying parSF
show Abstracthide Abstract
We report the genome-wide analysis from chromatin immunoprecipitated DNA (ChIP-sequencing) at very high resolution of the DNA binding pattern of ParBF (SopB) either on the full length plasmid F or on E. coli chromosome carrying the parSF centromere sequence. We also varied the intracellular ParBF concentration to discriminate between the several proposed mechanism of partition complexes assembly. Overall design: Differencial examination of ParBF binding by comparing input and IP (affinity-purified anti-ParBF antibody) samples
Sample: input_3586
SAMN09303691 • SRS3370386 • All experiments • All runs
Library:
Instrument: Ion S5
Strategy: ChIP-Seq
Source: GENOMIC
Selection: ChIP
Layout: SINGLE
Construction protocol: Lysates were clarified from sonicated cell and protein-DNA complexes were isolated with anti ParBF antibody A maximum of 2 ng of ChIP DNA was used to synthetize the library as described in manufacturer's instructions (Ion ChIP-Seq Library Preparation on the Ion Proton™ System - revision B - Step10). The last size selection was modified by a double size selection (0.55X/0.25X) of binding to AMPure® XP beads followed by a step of wash and elution. Then, qualification and quantification were made with the Bioanalyzer - Agilent, Santa Clara, CA
Experiment attributes:
GEO Accession: GSM3172972
Links:
Runs: 1 run, 7.9M spots, 1.4G bases, 781.5Mb
Run# of Spots# of BasesSizePublished
SRR72532167,856,1731.4G781.5Mb2018-10-30

ID:
5644596

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