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SRX18629698: GSM6808142: WT_RiboSeq_rep2; Saccharomyces cerevisiae; OTHER
1 ILLUMINA (NextSeq 550) run: 140.9M spots, 7.6G bases, 2.4Gb downloads

External Id: GSM6808142_r1
Submitted by: University of Bern
Study: RiboSeq and mSeq of two yeast strains
show Abstracthide Abstract
We report on how the absence of expansion segment 7S from the yeast ribosome alters A-site occupancy along transcripts. This has consequence for local translation rates and protein fidelity. Overall design: Examination of total and ribosome protected mRNA in wild-type and ?ES7S yeast yJD1045 strain depleted of genomic rDNA. rRNA is exclusively plasmid borne.
Sample: WT_RiboSeq_rep2
SAMN32132228 • SRS16076017 • All experiments • All runs
Library:
Name: GSM6808142
Instrument: NextSeq 550
Strategy: OTHER
Source: TRANSCRIPTOMIC
Selection: other
Layout: SINGLE
Construction protocol: Lysates were digested with RNAse1 and 80S ribosomes extracted from a density gradient after Ultracentrifugation. Size excluded RNA fragments were ligated to DeepSeq adapters. mRNA fragments ranging rom 24-28nt were size excluded and dephosphorylated. Adapters were ligated and the resulting fragments were circularized. cDNA was prepared with circRNA as input and PCR amplicification was performed for 4-8 cycles.
Runs: 1 run, 140.9M spots, 7.6G bases, 2.4Gb
Run# of Spots# of BasesSizePublished
SRR22666720140,877,1077.6G2.4Gb2024-05-01

ID:
25686864

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