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SRX14121135: GSM5884321: LAN757A15; Homo sapiens; RNA-Seq
1 ILLUMINA (Illumina HiSeq 4000) run: 24.3M spots, 2.5G bases, 1Gb downloads

External Id: GSM5884321_r1
Submitted by: Francis Crick Institute
Study: Transcriptomic analysis of human foetal hearts with or without Down Syndrome
PRJNA804915 • SRP359089 • All experiments • All runs
show Abstracthide Abstract
We performed bulk RNAseq on whole hearts from foetuses with Down syndrome and age-matched, sex-matched euploid controls. Analysis showed the expected increased expression of the genes on Hsa21 that are present in 3 copies. Gene set enrichment analysis identified pathways that are altered in DS hearts. Overall design: RNAseq on 5 human embryonic hearts with Down syndrome and on 5 euploid age- and sex-matched control hearts.
Sample: LAN757A15
SAMN25816052 • SRS11943966 • All experiments • All runs
Organism: Homo sapiens
Library:
Name: GSM5884321
Instrument: Illumina HiSeq 4000
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: cDNA
Layout: SINGLE
Construction protocol: samples were obtained and snap frozen and kept at -80C. Samples were lysed (buffer RLT Qiagen Rneasy Maxi kit) and homogenised using Macs Milteni M tubes and gentleMACS dissociator followed by RNA extraction using Qiagen Rneasy Maxi kit following the standard protocol
Runs: 1 run, 24.3M spots, 2.5G bases, 1Gb
Run# of Spots# of BasesSizePublished
SRR1796477324,345,1142.5G1Gb2024-01-26

ID:
19895080

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