show Abstracthide AbstractSummary: We sequenced mRNA from whole flies of females and male of Drosophila melanogaster, D. simulans, D. yakuba, D. ananassae, D. pseudobscura, D. mojavensis, and D. virilis as part of the modENCODE project to validate novel gene models found in D. melanogaster, identify genes differentially expressed between the sexes and sex-specific alternative splicing events, and examine the evolution of gene expression. Overall Design: Comparison of expresssion profiles in female and male whole flies. These are the same samples used to generate the array data found in GSE6640.