show Abstracthide AbstractThe degradation of freshwater ecosystems and decline in aquatic biodiversity is strongly associated with intensive land-use. Agricultural stressors such as pesticide contamination or increased fine sediment load can interact in complex ways and their combined effects are poorly understood. Single and combined effects of the insecticide chlorantraniliprole in three different concentrations and increased fine sediment load on the transcriptional profile of the amphipod Gammarus pulex was assessed. Mainly antagonistic stressor interactions at the transcriptomic level were identified, probably because the insecticide adsorbs to fine sediment particles, reducing its bioavailability for shredder organisms such as G. pulex. However, no clear response pattern was detectable for G. pulex in response to the stressor treatments.