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SRX252857: GSM1103228: Surface_fish_eye; Sinocyclocheilus angustiporus; RNA-Seq
1 ILLUMINA (Illumina HiSeq 2000) run: 49.2M spots, 9.3G bases, 4.9Gb downloads

Submitted by: Gene Expression Omnibus (GEO)
Study: Evolution of the eye transcriptome under constant darkness in Sinocyclocheilus cavefish
show Abstracthide Abstract
we report a transcriptome-wide comparative investigation between surface and cave species in Sinocyclocheilus. De novo transcriptome assemblies were performed on surface and cave species; then the Sinocyclocheilus contigs were annotated with Gene Ontology. RNA-Seq assays revealed reduced transcription of a series of visual phototransduction and retinal disease related genes in cave-dwelling species compared with surface species. Degeneration of the retina in Sinocyclocheilus cavefish might occur in a lens-independent way by the down-regulation of several transcriptional factors, which have direct roles in retina development and maintenance, such as crx, rorb and Wnt pathway members. Overall design: Examination of 2 different eye samples in 2 Sinocyclocheilus species.
Sample: Surface_fish_eye
SAMN01985057 • SRS403061 • All experiments • All runs
Library:
Instrument: Illumina HiSeq 2000
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: cDNA
Layout: PAIRED
Experiment attributes:
GEO Accession: GSM1103228
Links:
External link:
Runs: 1 run, 49.2M spots, 9.3G bases, 4.9Gb
Run# of Spots# of BasesSizePublished
SRR78809649,190,7889.3G4.9Gb2013-04-01

ID:
353411

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