show Abstracthide AbstractIn this study, the transcriptome of Hypomyces chrysospermus grown under 0 and 120 mg/L Cd stress was analyzed to identify differentially expressed genes (DEGs) associated with Cd adsorption and tolerance and to unravel the Cd stress response of Hypomyces chrysospermus in terms of the transcriptional expression of genes. Our findings would provide a theoretical basis for exploring the molecular mechanisms underlying Cd tolerance in Hypomyces chrysospermus.