Longitudinal detection of gait alterations associated with hypertension-induced cerebral microhemorrhages in mice: predictive role of stride length and stride time asymmetry and increased gait entropy.
Geroscience.
2024 Oct;46(5):4743-4760. doi: 10.1007/s11357-024-01210-3. Epub 2024 Jun 25. PubMed PMID:
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The effects of time restricted feeding on age-related changes in the mouse retina.
Exp Gerontol.
2024 Sep;194:112510. doi: 10.1016/j.exger.2024.112510. Epub 2024 Jul 5. PubMed PMID:
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Age- and sex- divergent translatomic responses of the mouse retinal pigmented epithelium.
Neurobiol Aging.
2024 Aug;140:41-59. doi: 10.1016/j.neurobiolaging.2024.04.012. Epub 2024 May 3. PubMed PMID:
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Flow Cytometry Analysis of Microglial Phenotypes in the Murine Brain During Aging and Disease.
Bio Protoc.
2024 Jun 20;14(12):e5018. doi: 10.21769/BioProtoc.5018. eCollection 2024 Jun 20. PubMed PMID:
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Vascular smooth muscle cell-specific Igf1r deficiency exacerbates the development of hypertension-induced cerebral microhemorrhages and gait defects.
Geroscience.
2024 Jun;46(3):3481-3501. doi: 10.1007/s11357-024-01090-7. Epub 2024 Feb 23. PubMed PMID:
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Mitochondrial calcium uniporter deficiency in dentate granule cells remodels neuronal metabolism and impairs reversal learning.
J Neurochem.
2024 May;168(5):592-607. doi: 10.1111/jnc.15901. Epub 2023 Jul 6. PubMed PMID:
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Brain energy metabolism: A roadmap for future research.
J Neurochem.
2024 May;168(5):910-954. doi: 10.1111/jnc.16032. Epub 2024 Jan 6. Review. PubMed PMID:
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Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction.
Adv Sci (Weinh).
2024 Mar;11(10):e2303516. doi: 10.1002/advs.202303516. Epub 2023 Dec 28. PubMed PMID:
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Sex difference in brain functional connectivity of hippocampus in Alzheimer's disease.
Geroscience.
2024 Feb;46(1):563-572. doi: 10.1007/s11357-023-00943-x. Epub 2023 Sep 25. PubMed PMID:
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Endothelial deficiency of insulin-like growth factor-1 receptor leads to blood-brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype.
Microcirculation.
2024 Feb;31(2):e12840. doi: 10.1111/micc.12840. Epub 2023 Dec 11. PubMed PMID:
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Microvascular smooth muscle cells exhibit divergent phenotypic switching responses to platelet-derived growth factor and insulin-like growth factor 1.
Microvasc Res.
2024 Jan;151:104609. doi: 10.1016/j.mvr.2023.104609. Epub 2023 Sep 15. PubMed PMID:
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Decision-Making in Clival Mass Lesions: Risk Factors for Malignant Disease and an Illustrative Case Example.
J Neurol Surg Rep.
2023 Oct;84(4):e156-e162. doi: 10.1055/a-2215-0974. eCollection 2023 Oct. PubMed PMID:
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Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age.
iScience.
2023 Dec 15;26(12):108413. doi: 10.1016/j.isci.2023.108413. eCollection 2023 Dec 15. PubMed PMID:
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Current limitations and future opportunities of tracer studies of muscle ageing.
J Physiol.
2023 Dec 5;. doi: 10.1113/JP285616. [Epub ahead of print] PubMed PMID:
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An institutional experience in applying quality improvement measures to pituitary surgery: clinical and resource implications.
Neurosurg Focus.
2023 Dec;55(6):E10. doi: 10.3171/2023.9.FOCUS23545. PubMed PMID:
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Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy.
J Cachexia Sarcopenia Muscle.
2023 Oct;14(5):2076-2089. doi: 10.1002/jcsm.13285. Epub 2023 Jul 14. PubMed PMID:
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Correction to: Microglial MHC‑I induction with aging and Alzheimer's is conserved in mouse models and humans.
Geroscience.
2023 Oct;45(5):3101-3102. doi: 10.1007/s11357-023-00881-8. PubMed PMID:
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Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin.
Geroscience.
2023 Oct;45(5):2851-2872. doi: 10.1007/s11357-023-00839-w. Epub 2023 Jun 20. PubMed PMID:
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Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
Geroscience.
2023 Oct;45(5):2983-3002. doi: 10.1007/s11357-023-00870-x. Epub 2023 Aug 29. PubMed PMID:
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Heterochronic Plasma Transfer: Experimental Design, Considerations, and Technical Challenges.
Rejuvenation Res.
2023 Oct;26(5):171-179. doi: 10.1089/rej.2023.0035. Epub 2023 Sep 25. Review. PubMed PMID:
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Consistent specificity and efficiency of tamoxifen-mediated cre induction across ages.
bioRxiv.
2023 Sep 22;. doi: 10.1101/2023.09.19.558482. PubMed PMID:
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Cerebral small vessel disease pathology in COVID-19 patients: A systematic review.
Ageing Res Rev.
2023 Jul;88:101962. doi: 10.1016/j.arr.2023.101962. Epub 2023 May 22. Review. PubMed PMID:
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Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
Aging Cell.
2023 Jul;22(7):e13832. doi: 10.1111/acel.13832. Epub 2023 May 26. PubMed PMID:
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Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans.
bioRxiv.
2023 Jun 2;. doi: 10.1101/2023.03.07.531435. PubMed PMID:
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Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter.
Geroscience.
2023 Jun;45(3):1491-1510. doi: 10.1007/s11357-023-00735-3. Epub 2023 Feb 16. PubMed PMID:
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Proopiomelanocortin projections to the nucleus accumbens modulate acquisition and maintenance of operant palatable pellet administration in mice.
Physiol Behav.
2023 Jun 1;265:114176. doi: 10.1016/j.physbeh.2023.114176. Epub 2023 Mar 23. PubMed PMID:
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Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection.
Front Immunol.
2023;14:1146690. doi: 10.3389/fimmu.2023.1146690. eCollection 2023. PubMed PMID:
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Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals.
J Appl Physiol (1985).
2023 Apr 1;134(4):1047-1062. doi: 10.1152/japplphysiol.00789.2022. Epub 2023 Feb 24. PubMed PMID:
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Chromosomal and gonadal factors regulate microglial sex effects in the aging brain.
Brain Res Bull.
2023 Apr;195:157-171. doi: 10.1016/j.brainresbull.2023.02.008. Epub 2023 Feb 15. Review. PubMed PMID:
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Cognitive heterogeneity reveals molecular signatures of age-related impairment.
PNAS Nexus.
2023 Apr;2(4):pgad101. doi: 10.1093/pnasnexus/pgad101. eCollection 2023 Apr. PubMed PMID:
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Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice.
bioRxiv.
2023 Mar 25;. doi: 10.1101/2023.03.25.534216. PubMed PMID:
36993459; PubMed Central PMCID:
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Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome.
J Vis Exp.
2023 Feb 24;(192). doi: 10.3791/64765. PubMed PMID:
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Cell non-autonomous regulation of cerebrovascular aging processes by the somatotropic axis.
Front Endocrinol (Lausanne).
2023;14:1087053. doi: 10.3389/fendo.2023.1087053. eCollection 2023. Review. PubMed PMID:
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Skeletal Muscle Nuclei in Mice are not Post-mitotic.
Function (Oxf).
2023;4(1):zqac059. doi: 10.1093/function/zqac059. eCollection 2023. PubMed PMID:
36569816; PubMed Central PMCID:
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Antecedent Metabolic Health and Metformin (ANTHEM) Aging Study: Rationale and Study Design for a Randomized Controlled Trial.
J Gerontol A Biol Sci Med Sci.
2022 Dec 29;77(12):2373-2377. doi: 10.1093/gerona/glab358. PubMed PMID:
34865016; PubMed Central PMCID:
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Scale-Free Functional Brain Networks Exhibit Increased Connectivity, Are More Integrated and Less Segregated in Patients with Parkinson's Disease following Dopaminergic Treatment.
Fractal Fract.
2022 Dec;6(12). doi: 10.3390/fractalfract6120737. Epub 2022 Dec 13. PubMed PMID:
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The role of age-associated autonomic dysfunction in inflammation and endothelial dysfunction.
Geroscience.
2022 Dec;44(6):2655-2670. doi: 10.1007/s11357-022-00616-1. Epub 2022 Jun 30. Review. PubMed PMID:
35773441; PubMed Central PMCID:
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Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food.
Neuropeptides.
2022 Dec;96:102289. doi: 10.1016/j.npep.2022.102289. Epub 2022 Sep 16. PubMed PMID:
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Translatomic response of retinal Müller glia to acute and chronic stress.
Neurobiol Dis.
2022 Dec;175:105931. doi: 10.1016/j.nbd.2022.105931. Epub 2022 Nov 22. PubMed PMID:
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Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults.
Geroscience.
2022 Dec;44(6):2771-2783. doi: 10.1007/s11357-022-00623-2. Epub 2022 Jul 23. PubMed PMID:
35869380; PubMed Central PMCID:
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Increased pulse wave velocity is related to impaired working memory and executive function in older adults with metabolic syndrome.
Geroscience.
2022 Dec;44(6):2831-2844. doi: 10.1007/s11357-022-00640-1. Epub 2022 Aug 18. PubMed PMID:
35980564; PubMed Central PMCID:
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A Pilot Analysis of Genome-Wide DNA Methylation Patterns in Mouse Cartilage Reveals Overlapping Epigenetic Signatures of Aging and Osteoarthritis.
ACR Open Rheumatol.
2022 Dec;4(12):1004-1012. doi: 10.1002/acr2.11506. Epub 2022 Oct 17. PubMed PMID:
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Decreased lifespan in female "Munchkin" actors from the cast of the 1939 film version of The Wizard of Oz does not support the hypothesis linking hypopituitary dwarfism to longevity.
Geroscience.
2022 Oct;44(5):2527-2539. doi: 10.1007/s11357-022-00680-7. Epub 2022 Nov 5. PubMed PMID:
36334178; PubMed Central PMCID:
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Sex differences in brain functional connectivity of hippocampus in mild cognitive impairment.
Front Aging Neurosci.
2022;14:959394. doi: 10.3389/fnagi.2022.959394. eCollection 2022. PubMed PMID:
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Selective Ablation of Sod2 in Astrocytes Induces Sex-Specific Effects on Cognitive Function, d-Serine Availability, and Astrogliosis.
J Neurosci.
2022 Aug 3;42(31):5992-6006. doi: 10.1523/JNEUROSCI.2543-21.2022. Epub 2022 Jun 27. PubMed PMID:
35760531; PubMed Central PMCID:
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Notch, Numb and Numb-like responses to exercise-induced muscle damage in human skeletal muscle.
Exp Physiol.
2022 Aug;107(8):800-806. doi: 10.1113/EP090364. Epub 2022 May 31. PubMed PMID:
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Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex.
Mol Neurobiol.
2022 Aug;59(8):4669-4702. doi: 10.1007/s12035-022-02860-0. Epub 2022 May 20. PubMed PMID:
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Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma.
Aging Cell.
2022 Aug;21(8):e13676. doi: 10.1111/acel.13676. Epub 2022 Jul 23. PubMed PMID:
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Delineating the Clinical Phenotype of Patients With the c.629C>G, p.Pro210Arg Mutation in Peripherin-2.
Invest Ophthalmol Vis Sci.
2022 Jul 8;63(8):19. doi: 10.1167/iovs.63.8.19. PubMed PMID:
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Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
Am J Physiol Heart Circ Physiol.
2022 Jun 1;322(6):H924-H935. doi: 10.1152/ajpheart.00616.2021. Epub 2022 Mar 25. PubMed PMID:
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