My Bibliography

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Deng PY, Kumar A, Cavalli V, Klyachko VA. Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model. bioRxiv. 2023 Nov 13;. doi: 10.1101/2023.09.27.559792. PubMed PMID: 37808793; PubMed Central PMCID: PMC10557679.

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Feng R, Muraleedharan Saraswathy V, Mokalled MH, Cavalli V. Self-renewing macrophages in dorsal root ganglia contribute to promote nerve regeneration. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2215906120. doi: 10.1073/pnas.2215906120. Epub 2023 Feb 10. PubMed PMID: 36763532; PubMed Central PMCID: PMC9963351.

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Avraham O, Chamessian A, Feng R, Yang L, Halevi AE, Moore AM, Gereau RW 4th, Cavalli V. Profiling the molecular signature of satellite glial cells at the single cell level reveals high similarities between rodents and humans. Pain. 2022 Dec 1;163(12):2348-2364. doi: 10.1097/j.pain.0000000000002628. Epub 2022 Mar 31. PubMed PMID: 35503034; PubMed Central PMCID: PMC9522926.

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Avraham O, Le J, Leahy K, Li T, Zhao G, Cavalli V. Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration. Front Mol Neurosci. 2022;15:967472. doi: 10.3389/fnmol.2022.967472. eCollection 2022. PubMed PMID: 36081575; PubMed Central PMCID: PMC9446241.

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Deng PY, Kumar A, Cavalli V, Klyachko VA. FMRP regulates GABA(A) receptor channel activity to control signal integration in hippocampal granule cells. Cell Rep. 2022 May 17;39(7):110820. doi: 10.1016/j.celrep.2022.110820. PubMed PMID: 35584668; PubMed Central PMCID: PMC9175534.

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Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. IL-33 signaling in sensory neurons promotes dry skin itch. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. PubMed PMID: 34560104; PubMed Central PMCID: PMC8934751.

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Avraham O, Deng PY, Maschi D, Klyachko VA, Cavalli V. Disrupted Association of Sensory Neurons With Enveloping Satellite Glial Cells in Fragile X Mouse Model. Front Mol Neurosci. 2021;14:796070. doi: 10.3389/fnmol.2021.796070. eCollection 2021. PubMed PMID: 35058748; PubMed Central PMCID: PMC8763968.

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Deng PY, Avraham O, Cavalli V, Klyachko VA. Hyperexcitability of Sensory Neurons in Fragile X Mouse Model. Front Mol Neurosci. 2021;14:796053. doi: 10.3389/fnmol.2021.796053. eCollection 2021. PubMed PMID: 35002623; PubMed Central PMCID: PMC8727524.

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Avraham O, Feng R, Ewan EE, Rustenhoven J, Zhao G, Cavalli V. Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for neural repair. Elife. 2021 Sep 29;10. doi: 10.7554/eLife.68457. PubMed PMID: 34586065; PubMed Central PMCID: PMC8480984.

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Pita-Thomas W, Gonçalves TM, Kumar A, Zhao G, Cavalli V. Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration. Sci Rep. 2021 Jul 21;11(1):14924. doi: 10.1038/s41598-021-94341-y. PubMed PMID: 34290335; PubMed Central PMCID: PMC8295311.

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Spears LD, Adak S, Dong G, Wei X, Spyropoulos G, Zhang Q, Yin L, Feng C, Hu D, Lodhi IJ, Hsu FF, Rajagopal R, Noguchi KK, Halabi CM, Brier L, Bice AR, Lananna BV, Musiek ES, Avraham O, Cavalli V, Holth JK, Holtzman DM, Wozniak DF, Culver JP, Semenkovich CF. Endothelial ether lipids link the vasculature to blood pressure, behavior, and neurodegeneration. J Lipid Res. 2021;62:100079. doi: 10.1016/j.jlr.2021.100079. Epub 2021 Apr 21. PubMed PMID: 33894211; PubMed Central PMCID: PMC8144742.

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Jeon Y, Shin JE, Kwon M, Cho E, Cavalli V, Cho Y. In Vivo Gene Delivery of STC2 Promotes Axon Regeneration in Sciatic Nerves. Mol Neurobiol. 2021 Feb;58(2):750-760. doi: 10.1007/s12035-020-02155-2. Epub 2020 Oct 4. PubMed PMID: 33011858.

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Ewan EE, Avraham O, Carlin D, Gonçalves TM, Zhao G, Cavalli V. Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism. Sci Rep. 2021 Jan 11;11(1):374. doi: 10.1038/s41598-020-79624-0. PubMed PMID: 33431991; PubMed Central PMCID: PMC7801468.

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Avraham O, Feng R, Ewan E, Zhao G, Cavalli V. Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for axon regeneration. [preprint]. 2020 November. doi: https://doi.org/10.1101/2020.11.25.398537.

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Miao ZF, Lewis MA, Cho CJ, Adkins-Threats M, Park D, Brown JW, Sun JX, Burclaff JR, Kennedy S, Lu J, Mahar M, Vietor I, Huber LA, Davidson NO, Cavalli V, Rubin DC, Wang ZN, Mills JC. A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle. Dev Cell. 2020 Oct 26;55(2):178-194.e7. doi: 10.1016/j.devcel.2020.07.005. Epub 2020 Aug 7. PubMed PMID: 32768422; PubMed Central PMCID: PMC7606764.

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Avraham O, Deng PY, Jones S, Kuruvilla R, Semenkovich CF, Klyachko VA, Cavalli V. Satellite glial cells promote regenerative growth in sensory neurons. Nat Commun. 2020 Sep 29;11(1):4891. doi: 10.1038/s41467-020-18642-y. PubMed PMID: 32994417; PubMed Central PMCID: PMC7524726.

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Balkunde R, Foroughi L, Ewan E, Emenecker R, Cavalli V, Dixit R. Mechanism of microtubule plus-end tracking by the plant-specific SPR1 protein and its development as a versatile plus-end marker. J Biol Chem. 2019 Nov 1;294(44):16374-16384. doi: 10.1074/jbc.RA119.008866. Epub 2019 Sep 16. PubMed PMID: 31527079; PubMed Central PMCID: PMC6827287.

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Pita-Thomas W, Mahar M, Joshi A, Gan D, Cavalli V. HDAC5 promotes optic nerve regeneration by activating the mTOR pathway. Exp Neurol. 2019 Jul;317:271-283. doi: 10.1016/j.expneurol.2019.03.011. Epub 2019 Mar 22. PubMed PMID: 30910408; PubMed Central PMCID: PMC6544474.

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Carlin D, Halevi AE, Ewan EE, Moore AM, Cavalli V. Nociceptor Deletion of Tsc2 Enhances Axon Regeneration by Inducing a Conditioning Injury Response in Dorsal Root Ganglia. eNeuro. 2019 May/Jun;6(3). doi: 10.1523/ENEURO.0168-19.2019. Print 2019 May/Jun. PubMed PMID: 31182472; PubMed Central PMCID: PMC6595439.

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Deng PY, Carlin D, Oh YM, Myrick LK, Warren ST, Cavalli V, Klyachko VA. Voltage-Independent SK-Channel Dysfunction Causes Neuronal Hyperexcitability in the Hippocampus of Fmr1 Knock-Out Mice. J Neurosci. 2019 Jan 2;39(1):28-43. doi: 10.1523/JNEUROSCI.1593-18.2018. Epub 2018 Nov 2. PubMed PMID: 30389838; PubMed Central PMCID: PMC6325266.

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Oh YM, Mahar M, Ewan EE, Leahy KM, Zhao G, Cavalli V. Epigenetic regulator UHRF1 inactivates REST and growth suppressor gene expression via DNA methylation to promote axon regeneration. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12417-E12426. doi: 10.1073/pnas.1812518115. Epub 2018 Dec 10. PubMed PMID: 30530687; PubMed Central PMCID: PMC6310844.

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Mahar M, Cavalli V. Intrinsic mechanisms of neuronal axon regeneration. Nat Rev Neurosci. 2018 Jun;19(6):323-337. doi: 10.1038/s41583-018-0001-8. Review. PubMed PMID: 29666508; PubMed Central PMCID: PMC5987780.

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Carlin D, Golden JP, Mogha A, Samineni VK, Monk KR, Gereau RW 4th, Cavalli V. Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat. eNeuro. 2018 Mar-Apr;5(2). doi: 10.1523/ENEURO.0436-17.2018. eCollection 2018 Mar-Apr. PubMed PMID: 29766046; PubMed Central PMCID: PMC5952427.

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Ban N, Siegfried CJ, Lin JB, Shui YB, Sein J, Pita-Thomas W, Sene A, Santeford A, Gordon M, Lamb R, Dong Z, Kelly SC, Cavalli V, Yoshino J, Apte RS. GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients. JCI Insight. 2017 May 4;2(9). doi: 10.1172/jci.insight.91455. eCollection 2017 May 4. PubMed PMID: 28469085; PubMed Central PMCID: PMC5414567.

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Pita-Thomas W, Barroso-García G, Moral V, Hackett AR, Cavalli V, Nieto-Diaz M. Identification of axon growth promoters in the secretome of the deer antler velvet. Neuroscience. 2017 Jan 6;340:333-344. doi: 10.1016/j.neuroscience.2016.10.063. Epub 2016 Nov 4. PubMed PMID: 27818162.

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Mogha A, Harty BL, Carlin D, Joseph J, Sanchez NE, Suter U, Piao X, Cavalli V, Monk KR. Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair. J Neurosci. 2016 Dec 7;36(49):12351-12367. doi: 10.1523/JNEUROSCI.3854-15.2016. PubMed PMID: 27927955; PubMed Central PMCID: PMC5148226.

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Saito A, Cavalli V. Signaling Over Distances. Mol Cell Proteomics. 2016 Feb;15(2):382-93. doi: 10.1074/mcp.R115.052753. Epub 2015 Aug 21. Review. PubMed PMID: 26297514; PubMed Central PMCID: PMC4739662.

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Cho Y, Shin JE, Ewan EE, Oh YM, Pita-Thomas W, Cavalli V. Activating Injury-Responsive Genes with Hypoxia Enhances Axon Regeneration through Neuronal HIF-1α. Neuron. 2015 Nov 18;88(4):720-34. doi: 10.1016/j.neuron.2015.09.050. Epub 2015 Oct 29. PubMed PMID: 26526390; PubMed Central PMCID: PMC4655162.

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Cho Y, Park D, Cavalli V. Filamin A is required in injured axons for HDAC5 activity and axon regeneration. J Biol Chem. 2015 Sep 11;290(37):22759-70. doi: 10.1074/jbc.M115.638445. Epub 2015 Jul 8. PubMed PMID: 26157139; PubMed Central PMCID: PMC4566247.

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O'Brien DE, Alter BJ, Satomoto M, Morgan CD, Davidson S, Vogt SK, Norman ME, Gereau GB, Demaro JA 3rd, Landreth GE, Golden JP, Gereau RW 4th. ERK2 Alone Drives Inflammatory Pain But Cooperates with ERK1 in Sensory Neuron Survival. J Neurosci. 2015 Jun 24;35(25):9491-507. doi: 10.1523/JNEUROSCI.4404-14.2015. PubMed PMID: 26109671; PubMed Central PMCID: PMC4478259.

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Watt D, Dixit R, Cavalli V. JIP3 Activates Kinesin-1 Motility to Promote Axon Elongation. J Biol Chem. 2015 Jun 19;290(25):15512-15525. doi: 10.1074/jbc.M115.651885. Epub 2015 May 5. PubMed PMID: 25944905; PubMed Central PMCID: PMC4505465.

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Song W, Cho Y, Watt D, Cavalli V. Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration. J Biol Chem. 2015 Jun 5;290(23):14765-75. doi: 10.1074/jbc.M114.622753. Epub 2015 Apr 24. PubMed PMID: 25911101; PubMed Central PMCID: PMC4505541.

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Myrick LK, Deng PY, Hashimoto H, Oh YM, Cho Y, Poidevin MJ, Suhl JA, Visootsak J, Cavalli V, Jin P, Cheng X, Warren ST, Klyachko VA. Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):949-56. doi: 10.1073/pnas.1423094112. Epub 2015 Jan 5. PubMed PMID: 25561520; PubMed Central PMCID: PMC4313821.

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Cho Y, Cavalli V. HDAC signaling in neuronal development and axon regeneration. Curr Opin Neurobiol. 2014 Aug;27:118-26. doi: 10.1016/j.conb.2014.03.008. Epub 2014 Apr 12. Review. PubMed PMID: 24727244; PubMed Central PMCID: PMC4122610.

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Cho Y, Di Liberto V, Carlin D, Abe N, Li KH, Burlingame AL, Guan S, Michaelevski I, Cavalli V. Syntaxin13 expression is regulated by mammalian target of rapamycin (mTOR) in injured neurons to promote axon regeneration. J Biol Chem. 2014 May 30;289(22):15820-32. doi: 10.1074/jbc.M113.536607. Epub 2014 Apr 15. PubMed PMID: 24737317; PubMed Central PMCID: PMC4140936.

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Cavalli V, Holtzman DM. B-RAF unlocks axon regeneration. J Exp Med. 2014 May 5;211(5):746. doi: 10.1084/jem.2115insight3. PubMed PMID: 24799531; PubMed Central PMCID: PMC4010911.

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Cho Y, Sloutsky R, Naegle KM, Cavalli V. Injury-induced HDAC5 nuclear export is essential for axon regeneration. Cell. 2013 Nov 7;155(4):894-908. doi: 10.1016/j.cell.2013.10.004. PubMed PMID: 24209626; PubMed Central PMCID: PMC3987749.

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Deng PY, Rotman Z, Blundon JA, Cho Y, Cui J, Cavalli V, Zakharenko SS, Klyachko VA. FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels. Neuron. 2013 Feb 20;77(4):696-711. doi: 10.1016/j.neuron.2012.12.018. PubMed PMID: 23439122; PubMed Central PMCID: PMC3584349.

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Kandaswamy U, Rotman Z, Watt D, Schillebeeckx I, Cavalli V, Klyachko VA. Automated condition-invariable neurite segmentation and synapse classification using textural analysis-based machine-learning algorithms. J Neurosci Methods. 2013 Feb 15;213(1):84-98. doi: 10.1016/j.jneumeth.2012.12.011. Epub 2012 Dec 20. PubMed PMID: 23261652; PubMed Central PMCID: PMC3721977.

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Shin JE, Miller BR, Babetto E, Cho Y, Sasaki Y, Qayum S, Russler EV, Cavalli V, Milbrandt J, DiAntonio A. SCG10 is a JNK target in the axonal degeneration pathway. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3696-705. doi: 10.1073/pnas.1216204109. Epub 2012 Nov 27. PubMed PMID: 23188802; PubMed Central PMCID: PMC3535671.

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Shin JE, Cho Y, Beirowski B, Milbrandt J, Cavalli V, DiAntonio A. Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. Neuron. 2012 Jun 21;74(6):1015-22. doi: 10.1016/j.neuron.2012.04.028. PubMed PMID: 22726832; PubMed Central PMCID: PMC3383631.

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Cho Y, Cavalli V. HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration. EMBO J. 2012 Jun 12;31(14):3063-78. doi: 10.1038/emboj.2012.160. PubMed PMID: 22692128; PubMed Central PMCID: PMC3400015.

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Di Liberto V, Cavalli V. Ready, STAT, go: transcription factors on the move. EMBO J. 2012 Mar 21;31(6):1331-3. doi: 10.1038/emboj.2012.34. Epub 2012 Feb 14. PubMed PMID: 22333913; PubMed Central PMCID: PMC3321183.

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Sun F, Zhu C, Dixit R, Cavalli V. Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility. EMBO J. 2011 Jul 12;30(16):3416-29. doi: 10.1038/emboj.2011.229. PubMed PMID: 21750526; PubMed Central PMCID: PMC3160654.

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Abe N, Borson SH, Gambello MJ, Wang F, Cavalli V. Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. J Biol Chem. 2010 Sep 3;285(36):28034-43. doi: 10.1074/jbc.M110.125336. Epub 2010 Jul 8. PubMed PMID: 20615870; PubMed Central PMCID: PMC2934668.

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Tuck E, Cavalli V. Roles of membrane trafficking in nerve repair and regeneration. Commun Integr Biol. 2010 May;3(3):209-14. doi: 10.4161/cib.3.3.11555. PubMed PMID: 20714395; PubMed Central PMCID: PMC2918758.

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Sun F, Cavalli V. Neuroproteomics approaches to decipher neuronal regeneration and degeneration. Mol Cell Proteomics. 2010 May;9(5):963-75. doi: 10.1074/mcp.R900003-MCP200. Epub 2009 Dec 17. Review. PubMed PMID: 20019051; PubMed Central PMCID: PMC2871427.

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Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V. Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem. 2009 Dec 11;284(50):34628-39. doi: 10.1074/jbc.M109.035022. Epub 2009 Sep 29. PubMed PMID: 19801628; PubMed Central PMCID: PMC2787325.

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Abe N, Cavalli V. Nerve injury signaling. Curr Opin Neurobiol. 2008 Jun;18(3):276-83. doi: 10.1016/j.conb.2008.06.005. Review. PubMed PMID: 18655834; PubMed Central PMCID: PMC2633416.

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Cavalli V. Transport dependent damage signaling. Encyclopedia of Neuroscience. 2008.