My Bibliography

select

Das PK, Kielian M. Rubella virus assembly requirements and evolutionary relationships with novel rubiviruses. mBio. 2024 Oct 16;15(10):e0196524. doi: 10.1128/mbio.01965-24. Epub 2024 Aug 29. PubMed PMID: 39207105; PubMed Central PMCID: PMC11481484.

select

Yin P, Martin CK, Kielian M. Virus stealth technology: Tools to study virus cell-to-cell transmission. PLoS Pathog. 2024 Oct;20(10):e1012590. doi: 10.1371/journal.ppat.1012590. eCollection 2024 Oct. Review. PubMed PMID: 39383183; PubMed Central PMCID: PMC11463765.

select

Yin P, May NA, Lello LS, Fayed A, Parks MG, Drobish AM, Wang S, Andrews M, Sticher Z, Kolykhalov AA, Natchus MG, Painter GR, Merits A, Kielian M, Morrison TE. 4'-Fluorouridine inhibits alphavirus replication and infection in vitro and in vivo. mBio. 2024 Jun 12;15(6):e0042024. doi: 10.1128/mbio.00420-24. Epub 2024 May 3. PubMed PMID: 38700353; PubMed Central PMCID: PMC11237586.

select

Das PK, Gonzalez PA, Jangra RK, Yin P, Kielian M. A single-point mutation in the rubella virus E1 glycoprotein promotes rescue of recombinant vesicular stomatitis virus. mBio. 2024 Mar 13;15(3):e0237323. doi: 10.1128/mbio.02373-23. Epub 2024 Feb 9. PubMed PMID: 38334805; PubMed Central PMCID: PMC10936182.

select

Yin P, Davenport BJ, Wan JJ, Kim AS, Diamond MS, Ware BC, Tong K, Couderc T, Lecuit M, Lai JR, Morrison TE, Kielian M. Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo. Nat Microbiol. 2023 Sep;8(9):1653-1667. doi: 10.1038/s41564-023-01449-0. Epub 2023 Aug 17. PubMed PMID: 37591996; PubMed Central PMCID: PMC10956380.

select

Cable J, Denison MR, Kielian M, Jackson WT, Bartenschlager R, Ahola T, Mukhopadhyay S, Fremont DH, Kuhn RJ, Shannon A, Frazier MN, Yuen KY, Coyne CB, Wolthers KC, Ming GL, Guenther CS, Moshiri J, Best SM, Schoggins JW, Jurado KA, Ebel GD, Schäfer A, Ng LFP, Kikkert M, Sette A, Harris E, Wing PAC, Eggenberger J, Krishnamurthy SR, Mah MG, Meganck RM, Chung D, Maurer-Stroh S, Andino R, Korber B, Perlman S, Shi PY, Bárcena M, Aicher SM, Vu MN, Kenney DJ, Lindenbach BD, Nishida Y, Rénia L, Williams EP. Positive-strand RNA viruses-a Keystone Symposia report. Ann N Y Acad Sci. 2023 Mar;1521(1):46-66. doi: 10.1111/nyas.14957. Epub 2023 Jan 25. PubMed PMID: 36697369; PubMed Central PMCID: PMC10347887.

select

Dowd KA, Sirohi D, Speer SD, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, Koenig S, Kielian M, Kuhn RJ, Diamond MS, Pierson TC. prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218899120. doi: 10.1073/pnas.2218899120. Epub 2023 Jan 13. PubMed PMID: 36638211; PubMed Central PMCID: PMC9933121.

select

Singh K, Martinez MG, Lin J, Gregory J, Nguyen TU, Abdelaal R, Kang K, Brennand K, Grünweller A, Ouyang Z, Phatnani H, Kielian M, Wendel HG. Transcriptional and Translational Dynamics of Zika and Dengue Virus Infection. Viruses. 2022 Jun 28;14(7). doi: 10.3390/v14071418. PubMed PMID: 35891396; PubMed Central PMCID: PMC9316442.

select

Martin CK, Kielian M. Identification of human and mosquito receptors for alphaviruses. Nature. 2022 Feb;602(7897):388-390. doi: 10.1038/d41586-022-00052-3. PubMed PMID: 35046583.

select

Rodriguez-Rodriguez BA, Noval MG, Kaczmarek ME, Jang KK, Thannickal SA, Cifuentes Kottkamp A, Brown RS, Kielian M, Cadwell K, Stapleford KA. Atovaquone and Berberine Chloride Reduce SARS-CoV-2 Replication In Vitro. Viruses. 2021 Dec 4;13(12). doi: 10.3390/v13122437. PubMed PMID: 34960706; PubMed Central PMCID: PMC8706021.

select

Malonis RJ, Earnest JT, Kim AS, Angeliadis M, Holtsberg FW, Aman MJ, Jangra RK, Chandran K, Daily JP, Diamond MS, Kielian M, Lai JR. Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37). doi: 10.1073/pnas.2100104118. PubMed PMID: 34507983; PubMed Central PMCID: PMC8449321.

select

Brown RS, Kim L, Kielian M. Specific Recognition of a Stem-Loop RNA Structure by the Alphavirus Capsid Protein. Viruses. 2021 Jul 31;13(8). doi: 10.3390/v13081517. PubMed PMID: 34452382; PubMed Central PMCID: PMC8402798.

select

Yin P, Kielian M. BHK-21 Cell Clones Differ in Chikungunya Virus Infection and MXRA8 Receptor Expression. Viruses. 2021 May 21;13(6). doi: 10.3390/v13060949. PubMed PMID: 34063936; PubMed Central PMCID: PMC8224076.

select

Das PK, Kielian M. Molecular and Structural Insights into the Life Cycle of Rubella Virus. J Virol. 2021 Apr 26;95(10). doi: 10.1128/JVI.02349-20. Epub 2021 Feb 24. Review. PubMed PMID: 33627388; PubMed Central PMCID: PMC8139664.

select

Das PK, Kielian M. The Enigmatic Capsid Protein of an Encephalitic Rubivirus. J Virol. 2021 Mar 25;95(8). doi: 10.1128/JVI.02294-20. Epub 2021 Jan 20. PubMed PMID: 33472932; PubMed Central PMCID: PMC8103679.

select

Kielian M. Enhancing host cell infection by SARS-CoV-2. Science. 2020 Nov 13;370(6518):765-766. doi: 10.1126/science.abf0732. PubMed PMID: 33184193.

select

Brown RS, Anastasakis DG, Hafner M, Kielian M. Multiple capsid protein binding sites mediate selective packaging of the alphavirus genomic RNA. Nat Commun. 2020 Sep 17;11(1):4693. doi: 10.1038/s41467-020-18447-z. PubMed PMID: 32943634; PubMed Central PMCID: PMC7499256.

select

Wan JJ, Brown RS, Kielian M. Berberine Chloride is an Alphavirus Inhibitor That Targets Nucleocapsid Assembly. mBio. 2020 Jun 30;11(3). doi: 10.1128/mBio.01382-20. PubMed PMID: 32605989; PubMed Central PMCID: PMC7327175.

select

Quiroz JA, Malonis RJ, Thackray LB, Cohen CA, Pallesen J, Jangra RK, Brown RS, Hofmann D, Holtsberg FW, Shulenin S, Nyakatura EK, Durnell LA, Rayannavar V, Daily JP, Ward AB, Aman MJ, Dye JM, Chandran K, Diamond MS, Kielian M, Lai JR. Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins. PLoS Pathog. 2019 Nov;15(11):e1008061. doi: 10.1371/journal.ppat.1008061. eCollection 2019 Nov. PubMed PMID: 31697791; PubMed Central PMCID: PMC6837291.

select

Prado Acosta M, Geoghegan EM, Lepenies B, Ruzal S, Kielian M, Martinez MG. Surface (S) Layer Proteins of Lactobacillus acidophilus Block Virus Infection via DC-SIGN Interaction. Front Microbiol. 2019;10:810. doi: 10.3389/fmicb.2019.00810. eCollection 2019. PubMed PMID: 31040840; PubMed Central PMCID: PMC6477042.

select

Wan JJ, Ooi YS, Kielian M. Mechanism of Tetherin Inhibition of Alphavirus Release. J Virol. 2019 Apr 1;93(7). doi: 10.1128/JVI.02165-18. Print 2019 Apr 1. PubMed PMID: 30674629; PubMed Central PMCID: PMC6430530.

select

Byrd EA, Kielian M. The Alphavirus E2 Membrane-Proximal Domain Impacts Capsid Interaction and Glycoprotein Lattice Formation. J Virol. 2019 Feb 15;93(4). doi: 10.1128/JVI.01881-18. Print 2019 Feb 15. PubMed PMID: 30463969; PubMed Central PMCID: PMC6364017.

select

Badolo A, Burt F, Daniel S, Fearns R, Gudo ES, Kielian M, Lescar J, Shi Y, von Brunn A, Weiss SR, Hilgenfeld R. Third Tofo Advanced Study Week on Emerging and Re-emerging Viruses, 2018. Antiviral Res. 2019 Feb;162:142-150. doi: 10.1016/j.antiviral.2018.12.015. Epub 2018 Dec 28. Review. PubMed PMID: 30597184; PubMed Central PMCID: PMC7132404.

select

Frei JC, Wirchnianski AS, Govero J, Vergnolle O, Dowd KA, Pierson TC, Kielian M, Girvin ME, Diamond MS, Lai JR. Engineered Dengue Virus Domain III Proteins Elicit Cross-Neutralizing Antibody Responses in Mice. J Virol. 2018 Sep 15;92(18). doi: 10.1128/JVI.01023-18. Print 2018 Sep 15. PubMed PMID: 29976679; PubMed Central PMCID: PMC6146717.

select

Vanegas JM, Heinrich F, Rogers DM, Carson BD, La Bauve S, Vernon BC, Akgun B, Satija S, Zheng A, Kielian M, Rempe SB, Kent MS. Insertion of Dengue E into lipid bilayers studied by neutron reflectivity and molecular dynamics simulations. Biochim Biophys Acta Biomembr. 2018 May;1860(5):1216-1230. doi: 10.1016/j.bbamem.2018.02.012. Epub 2018 Feb 13. PubMed PMID: 29447917; PubMed Central PMCID: PMC6532988.

select

Brown RS, Wan JJ, Kielian M. The Alphavirus Exit Pathway: What We Know and What We Wish We Knew. Viruses. 2018 Feb 22;10(2). doi: 10.3390/v10020089. Review. PubMed PMID: 29470397; PubMed Central PMCID: PMC5850396.

select

Mettenleiter TC, Kielian M, Roossinck MJ. Preface to Volume 100: History and Looking Forward. Adv Virus Res. 2018;100:xv-xxiv. doi: 10.1016/S0065-3527(18)30021-6. PubMed PMID: 29551146.

select

Byrd EA, Kielian M. An Alphavirus E2 Membrane-Proximal Domain Promotes Envelope Protein Lateral Interactions and Virus Budding. mBio. 2017 Nov 7;8(6). doi: 10.1128/mBio.01564-17. PubMed PMID: 29114027; PubMed Central PMCID: PMC5676042.

select

Martinez MG, Kielian M. Intercellular Extensions Are Induced by the Alphavirus Structural Proteins and Mediate Virus Transmission. PLoS Pathog. 2016 Dec;12(12):e1006061. doi: 10.1371/journal.ppat.1006061. eCollection 2016 Dec. PubMed PMID: 27977778; PubMed Central PMCID: PMC5158078.

select

Bauve E, Vernon BC, Ye D, Rogers DM, Siegrist CM, Carson BD, Rempe SB, Zheng A, Kielian M, Shreve AP, Kent MS. Method for measuring the unbinding energy of strongly-bound membrane-associated proteins. Biochim Biophys Acta. 2016 Nov;1858(11):2753-2762. doi: 10.1016/j.bbamem.2016.07.004. Epub 2016 Jul 15. PubMed PMID: 27425029; PubMed Central PMCID: PMC5266593.

select

Dubé M, Etienne L, Fels M, Kielian M. Calcium-Dependent Rubella Virus Fusion Occurs in Early Endosomes. J Virol. 2016 Jul 15;90(14):6303-6313. doi: 10.1128/JVI.00634-16. Print 2016 Jul 15. PubMed PMID: 27122589; PubMed Central PMCID: PMC4936153.

select

Stiles KM, Kielian M. Role of TSPAN9 in Alphavirus Entry and Early Endosomes. J Virol. 2016 May;90(9):4289-97. doi: 10.1128/JVI.00018-16. Print 2016 May. PubMed PMID: 26865714; PubMed Central PMCID: PMC4836341.

select

Fields W, Kielian M. Interactions involved in pH protection of the alphavirus fusion protein. Virology. 2015 Dec;486:173-9. doi: 10.1016/j.virol.2015.08.028. Epub 2015 Oct 2. PubMed PMID: 26433749; PubMed Central PMCID: PMC4679575.

select

Kielian M, Saphire EO. Potent Antibody Protection against an Emerging Alphavirus Threat. Cell. 2015 Nov 19;163(5):1053-1054. doi: 10.1016/j.cell.2015.11.006. PubMed PMID: 26590413.

select

Frei JC, Kielian M, Lai JR. Comprehensive mapping of functional epitopes on dengue virus glycoprotein E DIII for binding to broadly neutralizing antibodies 4E11 and 4E5A by phage display. Virology. 2015 Nov;485:371-82. doi: 10.1016/j.virol.2015.08.011. Epub 2015 Sep 2. PubMed PMID: 26339794; PubMed Central PMCID: PMC4619145.

select

Zheng Y, Kielian M. An alphavirus temperature-sensitive capsid mutant reveals stages of nucleocapsid assembly. Virology. 2015 Oct;484:412-420. doi: 10.1016/j.virol.2015.05.011. Epub 2015 Jun 6. PubMed PMID: 26051211; PubMed Central PMCID: PMC4567448.

select

Kleinfelter LM, Jangra RK, Jae LT, Herbert AS, Mittler E, Stiles KM, Wirchnianski AS, Kielian M, Brummelkamp TR, Dye JM, Chandran K. Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion. mBio. 2015 Jun 30;6(4):e00801. doi: 10.1128/mBio.00801-15. PubMed PMID: 26126854; PubMed Central PMCID: PMC4488941.

select

Ooi YS, Dubé M, Kielian M. BST2/tetherin inhibition of alphavirus exit. Viruses. 2015 Apr 22;7(4):2147-67. doi: 10.3390/v7042147. PubMed PMID: 25912717; PubMed Central PMCID: PMC4411694.

select

Dubé M, Rey FA, Kielian M. Rubella virus: first calcium-requiring viral fusion protein. PLoS Pathog. 2014 Dec;10(12):e1004530. doi: 10.1371/journal.ppat.1004530. eCollection 2014 Dec. PubMed PMID: 25474548; PubMed Central PMCID: PMC4256232.

select

Kielian M. Mechanisms of Virus Membrane Fusion Proteins. Annu Rev Virol. 2014 Nov;1(1):171-89. doi: 10.1146/annurev-virology-031413-085521. Epub 2014 Jun 24. PubMed PMID: 26958720.

select

Martinez MG, Snapp EL, Perumal GS, Macaluso FP, Kielian M. Imaging the alphavirus exit pathway. J Virol. 2014 Jun;88(12):6922-33. doi: 10.1128/JVI.00592-14. Epub 2014 Apr 2. PubMed PMID: 24696489; PubMed Central PMCID: PMC4054368.

select

Zheng A, Yuan F, Kleinfelter LM, Kielian M. A toggle switch controls the low pH-triggered rearrangement and maturation of the dengue virus envelope proteins. Nat Commun. 2014 May 20;5:3877. doi: 10.1038/ncomms4877. PubMed PMID: 24846574; PubMed Central PMCID: PMC4063126.

select

Ooi YS, Stiles KM, Liu CY, Taylor GM, Kielian M. Genome-wide RNAi screen identifies novel host proteins required for alphavirus entry. PLoS Pathog. 2013;9(12):e1003835. doi: 10.1371/journal.ppat.1003835. Epub 2013 Dec 19. PubMed PMID: 24367265; PubMed Central PMCID: PMC3868536.

select

Uchime O, Fields W, Kielian M. The role of E3 in pH protection during alphavirus assembly and exit. J Virol. 2013 Sep;87(18):10255-62. doi: 10.1128/JVI.01507-13. Epub 2013 Jul 17. PubMed PMID: 23864626; PubMed Central PMCID: PMC3754015.

select

Zheng Y, Kielian M. Imaging of the alphavirus capsid protein during virus replication. J Virol. 2013 Sep;87(17):9579-89. doi: 10.1128/JVI.01299-13. Epub 2013 Jun 19. PubMed PMID: 23785213; PubMed Central PMCID: PMC3754095.

select

Sánchez-San Martín C, Nanda S, Zheng Y, Fields W, Kielian M. Cross-inhibition of chikungunya virus fusion and infection by alphavirus E1 domain III proteins. J Virol. 2013 Jul;87(13):7680-7. doi: 10.1128/JVI.00814-13. Epub 2013 May 1. PubMed PMID: 23637415; PubMed Central PMCID: PMC3700285.

select

Vigant F, Lee J, Hollmann A, Tanner LB, Akyol Ataman Z, Yun T, Shui G, Aguilar HC, Zhang D, Meriwether D, Roman-Sosa G, Robinson LR, Juelich TL, Buczkowski H, Chou S, Castanho MA, Wolf MC, Smith JK, Banyard A, Kielian M, Reddy S, Wenk MR, Selke M, Santos NC, Freiberg AN, Jung ME, Lee B. A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion. PLoS Pathog. 2013;9(4):e1003297. doi: 10.1371/journal.ppat.1003297. Epub 2013 Apr 18. PubMed PMID: 23637597; PubMed Central PMCID: PMC3630091.

select

Fields W, Kielian M. A key interaction between the alphavirus envelope proteins responsible for initial dimer dissociation during fusion. J Virol. 2013 Apr;87(7):3774-81. doi: 10.1128/JVI.03310-12. Epub 2013 Jan 16. PubMed PMID: 23325694; PubMed Central PMCID: PMC3624238.

select

Pierson TC, Kielian M. Flaviviruses: braking the entering. Curr Opin Virol. 2013 Feb;3(1):3-12. doi: 10.1016/j.coviro.2012.12.001. Epub 2013 Jan 24. Review. PubMed PMID: 23352692; PubMed Central PMCID: PMC3601797.

select

Liu CY, Kielian M. Identification of a specific region in the e1 fusion protein involved in zinc inhibition of semliki forest virus fusion. J Virol. 2012 Apr;86(7):3588-94. doi: 10.1128/JVI.07115-11. Epub 2012 Jan 18. PubMed PMID: 22258261; PubMed Central PMCID: PMC3302541.