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James S, Sanggaard S, Akif A, Mishra SK, Sanganahalli BG, Blumenfeld H, Verhagen JV, Hyder F, Herman P. Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb. J Cereb Blood Flow Metab. 2023 Nov;43(11):1891-1904. doi: 10.1177/0271678X231183887. Epub 2023 Jun 21. PubMed PMID: 37340791; PubMed Central PMCID: PMC10676132.
Schaper FLWVJ, Nordberg J, Cohen AL, Lin C, Hsu J, Horn A, Ferguson MA, Siddiqi SH, Drew W, Soussand L, Winkler AM, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon AJ, Ackermans L, Bubrick EJ, Peters JM, Wu O, Rost NS, Grafman J, Blumenfeld H, Temel Y, Rouhl RPW, Joutsa J, Fox MD. Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurol. 2023 Sep 1;80(9):891-902. doi: 10.1001/jamaneurol.2023.1988. PubMed PMID: 37399040; PubMed Central PMCID: PMC10318550.
Krestel H, Schreier DR, Sakiri E, von Allmen A, Abukhadra Y, Nirkko A, Steinlin M, Rosenow F, Markhus R, Schneider G, Jagella C, Mathis J, Blumenfeld H. Predictive Power of Interictal Epileptiform Discharges in Fitness-to-Drive Evaluation. Neurology. 2023 Aug 29;101(9):e866-e878. doi: 10.1212/WNL.0000000000207531. Epub 2023 Jul 6. PubMed PMID: 37414567; PubMed Central PMCID: PMC10501101.
Chen Y, Li S, Ge W, Jing J, Chen HY, Doherty D, Herman A, Kaleem S, Ding K, Osman G, Swisher CB, Smith C, Maciel CB, Alkhachroum A, Lee JW, Dhakar MB, Gilmore EJ, Sivaraju A, Hirsch LJ, Omay SB, Blumenfeld H, Sheth KN, Struck AF, Edlow BL, Westover MB, Kim JA. Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy. J Neurol Neurosurg Psychiatry. 2023 Mar;94(3):245-249. doi: 10.1136/jnnp-2022-329542. Epub 2022 Oct 14. PubMed PMID: 36241423; PubMed Central PMCID: PMC9931627.
Melloni L, Mudrik L, Pitts M, Bendtz K, Ferrante O, Gorska U, Hirschhorn R, Khalaf A, Kozma C, Lepauvre A, Liu L, Mazumder D, Richter D, Zhou H, Blumenfeld H, Boly M, Chalmers DJ, Devore S, Fallon F, de Lange FP, Jensen O, Kreiman G, Luo H, Panagiotaropoulos TI, Dehaene S, Koch C, Tononi G. An adversarial collaboration protocol for testing contrasting predictions of global neuronal workspace and integrated information theory. PLoS One. 2023;18(2):e0268577. doi: 10.1371/journal.pone.0268577. eCollection 2023. PubMed PMID: 36763595; PubMed Central PMCID: PMC9916582.
Khalaf A, Kronemer SI, Christison-Lagay K, Kwon H, Li J, Wu K, Blumenfeld H. Early neural activity changes associated with stimulus detection during visual conscious perception. Cereb Cortex. 2023 Feb 7;33(4):1347-1360. doi: 10.1093/cercor/bhac140. PubMed PMID: 35446937.
Blumenfeld H. Brain Mechanisms of Conscious Awareness: Detect, Pulse, Switch, and Wave. Neuroscientist. 2023 Feb;29(1):9-18. doi: 10.1177/10738584211049378. Epub 2021 Oct 11. PubMed PMID: 34632846; PubMed Central PMCID: PMC8995398.
McCafferty C, Gruenbaum BF, Tung R, Li JJ, Zheng X, Salvino P, Vincent P, Kratochvil Z, Ryu JH, Khalaf A, Swift K, Akbari R, Islam W, Antwi P, Johnson EA, Vitkovskiy P, Sampognaro J, Freedman IG, Kundishora A, Depaulis A, David F, Crunelli V, Sanganahalli BG, Herman P, Hyder F, Blumenfeld H. Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures. Nat Commun. 2023 Jan 10;14(1):117. doi: 10.1038/s41467-022-35535-4. PubMed PMID: 36627270; PubMed Central PMCID: PMC9832004.
Juan E, Górska U, Kozma C, Papantonatos C, Bugnon T, Denis C, Kremen V, Worrell G, Struck AF, Bateman LM, Merricks EM, Blumenfeld H, Tononi G, Schevon C, Boly M. Distinct signatures of loss of consciousness in focal impaired awareness versus tonic-clonic seizures. Brain. 2023 Jan 5;146(1):109-123. doi: 10.1093/brain/awac291. PubMed PMID: 36383415; PubMed Central PMCID: PMC10582624.
Kronemer SI, Aksen M, Ding JZ, Ryu JH, Xin Q, Ding Z, Prince JS, Kwon H, Khalaf A, Forman S, Jin DS, Wang K, Chen K, Hu C, Agarwal A, Saberski E, Wafa SMA, Morgan OP, Wu J, Christison-Lagay KL, Hasulak N, Morrell M, Urban A, Todd Constable R, Pitts M, Mark Richardson R, Crowley MJ, Blumenfeld H. Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity. Nat Commun. 2022 Nov 29;13(1):7342. doi: 10.1038/s41467-022-35117-4. PubMed PMID: 36446792; PubMed Central PMCID: PMC9707162.
Springer M, Khalaf A, Vincent P, Ryu JH, Abukhadra Y, Beniczky S, Glauser T, Krestel H, Blumenfeld H. A machine-learning approach for predicting impaired consciousness in absence epilepsy. Ann Clin Transl Neurol. 2022 Oct;9(10):1538-1550. doi: 10.1002/acn3.51647. Epub 2022 Sep 16. PubMed PMID: 36114696; PubMed Central PMCID: PMC9539371.
Gusso MM, Christison-Lagay KL, Zuckerman D, Chandrasekaran G, Kronemer SI, Ding JZ, Freedman NC, Nohama P, Blumenfeld H. More than a feeling: Scalp EEG and eye signals in conscious tactile perception. Conscious Cogn. 2022 Oct;105:103411. doi: 10.1016/j.concog.2022.103411. Epub 2022 Sep 22. PubMed PMID: 36156359.
Contreras Ramirez V, Patedakis Litvinov B, Gunawardane NA, Zhao CW, Yotter C, Quraishi IH, Blumenfeld H. Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing. Epileptic Disord. 2022 Oct 1;24(5):899-905. doi: 10.1684/epd.2022.1472. PubMed PMID: 35904040; PubMed Central PMCID: PMC10042123.
Janacsek K, Evans TM, Kiss M, Shah L, Blumenfeld H, Ullman MT. Subcortical Cognition: The Fruit Below the Rind. Annu Rev Neurosci. 2022 Jul 8;45:361-386. doi: 10.1146/annurev-neuro-110920-013544. Epub 2022 Apr 6. Review. PubMed PMID: 35385670.
Sivaraju A, Hirsch L, Gaspard N, Farooque P, Gerrard J, Xu Y, Deng Y, Damisah E, Blumenfeld H, Spencer DD. Factors Predicting Outcome After Intracranial EEG Evaluation in Patients With Medically Refractory Epilepsy. Neurology. 2022 Jul 5;99(1):e1-e10. doi: 10.1212/WNL.0000000000200569. Epub 2022 May 4. PubMed PMID: 35508395; PubMed Central PMCID: PMC9259091.
Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. doi: 10.1684/epd.2022.1430. PubMed PMID: 35770761.
Sanganahalli BG, Thompson GJ, Parent M, Verhagen JV, Blumenfeld H, Herman P, Hyder F. Thalamic activations in rat brain by fMRI during tactile (forepaw, whisker) and non-tactile (visual, olfactory) sensory stimulations. PLoS One. 2022;17(5):e0267916. doi: 10.1371/journal.pone.0267916. eCollection 2022. PubMed PMID: 35522646; PubMed Central PMCID: PMC9075615.
Contreras Ramirez V, Vaddiparti A, Blumenfeld H. Testing awareness in focal seizures: Clinical practice and interpretation of current guidelines. Ann Clin Transl Neurol. 2022 May;9(5):762-765. doi: 10.1002/acn3.51552. Epub 2022 Apr 29. PubMed PMID: 35485201; PubMed Central PMCID: PMC9082375.
Zhao CW, Gebre R, Baykara Y, Chen W, Vitkovskiy P, Li N, Johnson M, Chen EY, Kluger D, Blumenfeld H. Reliability of patient self-report of cognition, awareness, and consciousness during seizures. Ann Clin Transl Neurol. 2022 Jan;9(1):16-29. doi: 10.1002/acn3.51485. Epub 2022 Jan 11. PubMed PMID: 35014222; PubMed Central PMCID: PMC8791805.
Kumar A, Martin R, Chen W, Bauerschmidt A, Youngblood MW, Cunningham C, Si Y, Ezeani C, Kratochvil Z, Bronen J, Thomson J, Riordan K, Yoo JY, Shirka R, Manganas L, Krestel H, Hirsch LJ, Blumenfeld H. Simulated driving in the epilepsy monitoring unit: Effects of seizure type, consciousness, and motor impairment. Epilepsia. 2022 Jan;63(1):e30-e34. doi: 10.1111/epi.17136. Epub 2021 Nov 24. PubMed PMID: 34816425; PubMed Central PMCID: PMC8883409.
Kwon H, Kronemer SI, Christison-Lagay KL, Khalaf A, Li J, Ding JZ, Freedman NC, Blumenfeld H. Early cortical signals in visual stimulus detection. Neuroimage. 2021 Dec 1;244:118608. doi: 10.1016/j.neuroimage.2021.118608. Epub 2021 Sep 21. PubMed PMID: 34560270.
Martin RA, Cukiert A, Blumenfeld H. Short-term changes in cortical physiological arousal measured by electroencephalography during thalamic centromedian deep brain stimulation. Epilepsia. 2021 Nov;62(11):2604-2614. doi: 10.1111/epi.17042. Epub 2021 Aug 18. PubMed PMID: 34405892.
Blumenfeld H. Arousal and Consciousness in Focal Seizures. Epilepsy Curr. 2021 Oct;21(5):353-359. doi: 10.1177/15357597211029507. eCollection 2021 Oct. PubMed PMID: 34924835; PubMed Central PMCID: PMC8655266.
Gummadavelli A, Martin R, Goshay D, Sieu LA, Xu J, Gruenbaum BF, McCafferty C, Gerrard JL, Blumenfeld H. Cortical low-frequency power correlates with behavioral impairment in animal model of focal limbic seizures. Epilepsia. 2021 Aug;62(8):1960-1970. doi: 10.1111/epi.16964. Epub 2021 Jul 9. PubMed PMID: 34240747; PubMed Central PMCID: PMC8349876.
Li R, Ryu JH, Vincent P, Springer M, Kluger D, Levinsohn EA, Chen Y, Chen H, Blumenfeld H. The pulse: transient fMRI signal increases in subcortical arousal systems during transitions in attention. Neuroimage. 2021 May 15;232:117873. doi: 10.1016/j.neuroimage.2021.117873. Epub 2021 Feb 27. PubMed PMID: 33647499; PubMed Central PMCID: PMC8278331.
Gruenbaum BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, Schonwald A, Kurup A, Gruenbaum SE, Freedman IG, Funaro MC, Blumenfeld H, Sanacora G. Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality. Epilepsia. 2021 May;62(5):1041-1056. doi: 10.1111/epi.16862. Epub 2021 Mar 10. PubMed PMID: 33751566; PubMed Central PMCID: PMC8443164.
Zhao CW, Feng L, Sieu LA, Pok B, Gummadavelli A, Blumenfeld H. Parallel pathways to decreased subcortical arousal in focal limbic seizures. Epilepsia. 2020 Dec;61(12):e186-e191. doi: 10.1111/epi.16697. Epub 2020 Nov 9. PubMed PMID: 33165921; PubMed Central PMCID: PMC8491398.
Yan Q, Gaspard N, Zaveri HP, Blumenfeld H, Hirsch LJ, Spencer DD, Alkawadri R. The connectivity index: an effective metric for grading epileptogenicity. J Neurosurg. 2020 Oct 1;133(4):971-978. doi: 10.3171/2019.4.JNS195. Print 2020 Oct 1. PubMed PMID: 31561212.
Xu J, Galardi MM, Pok B, Patel KK, Zhao CW, Andrews JP, Singla S, McCafferty CP, Feng L, Musonza ET, Kundishora AJ, Gummadavelli A, Gerrard JL, Laubach M, Schiff ND, Blumenfeld H. Thalamic Stimulation Improves Postictal Cortical Arousal and Behavior. J Neurosci. 2020 Sep 16;40(38):7343-7354. doi: 10.1523/JNEUROSCI.1370-20.2020. Epub 2020 Aug 21. PubMed PMID: 32826310; PubMed Central PMCID: PMC7534908.
Wang I, Bernasconi A, Bernhardt B, Blumenfeld H, Cendes F, Chinvarun Y, Jackson G, Morgan V, Rampp S, Vaudano AE, Federico P. MRI essentials in epileptology: a review from the ILAE Imaging Taskforce. Epileptic Disord. 2020 Aug 1;22(4):421-437. doi: 10.1684/epd.2020.1174. Review. PubMed PMID: 32763869.
Singla S, Garcia GE, Rovenolt GE, Soto AL, Gilmore EJ, Hirsch LJ, Blumenfeld H, Sheth KN, Omay SB, Struck AF, Westover MB, Kim JA. Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury. Curr Neurol Neurosci Rep. 2020 Jul 27;20(9):42. doi: 10.1007/s11910-020-01060-4. Review. PubMed PMID: 32715371; PubMed Central PMCID: PMC9353690.
Yue Z, Freedman IG, Vincent P, Andrews JP, Micek C, Aksen M, Martin R, Zuckerman D, Perrenoud Q, Neske GT, Sieu LA, Bo X, Cardin JA, Blumenfeld H. Up and Down States of Cortical Neurons in Focal Limbic Seizures. Cereb Cortex. 2020 May 14;30(5):3074-3086. doi: 10.1093/cercor/bhz295. PubMed PMID: 31800015; PubMed Central PMCID: PMC7197089.
Tolchin B, Baslet G, Martino S, Suzuki J, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA. Motivational Interviewing Techniques to Improve Psychotherapy Adherence and Outcomes for Patients With Psychogenic Nonepileptic Seizures. J Neuropsychiatry Clin Neurosci. 2020 Spring;32(2):125-131. doi: 10.1176/appi.neuropsych.19020045. Epub 2019 Aug 30. Review. PubMed PMID: 31466516.
Cohen E, Antwi P, Banz BC, Vincent P, Saha R, Arencibia CA, Ryu JH, Atac E, Saleem N, Tomatsu S, Swift K, Hu C, Krestel H, Farooque P, Levy S, Wu J, Crowley M, Vaca FE, Blumenfeld H. Realistic driving simulation during generalized epileptiform discharges to identify electroencephalographic features related to motor vehicle safety: Feasibility and pilot study. Epilepsia. 2020 Jan;61(1):19-28. doi: 10.1111/epi.16356. Epub 2019 Oct 24. PubMed PMID: 31646628; PubMed Central PMCID: PMC7424790.
Saleem MN, Arencibia CA, McKenna K, Cristofaro S, Detyniecki K, Friedman D, French J, Blumenfeld H. Investigation of patient and observer agreement on description of seizures at initial clinical visit. Ann Clin Transl Neurol. 2019 Dec;6(12):2601-2606. doi: 10.1002/acn3.50950. Epub 2019 Dec 5. PubMed PMID: 31808615; PubMed Central PMCID: PMC6917334.
Sheikh Z, Blumenfeld H, Hirsch LJ. Contralateral ictal ptosis: Is it a reliable lateralizing sign in epilepsy?. Neurol Clin Pract. 2019 Dec;9(6):513-515. doi: 10.1212/CPJ.0000000000000690. PubMed PMID: 32042495; PubMed Central PMCID: PMC6927437.
Li J, Kronemer SI, Herman WX, Kwon H, Ryu JH, Micek C, Wu Y, Gerrard J, Spencer DD, Blumenfeld H. Default mode and visual network activity in an attention task: Direct measurement with intracranial EEG. Neuroimage. 2019 Nov 1;201:116003. doi: 10.1016/j.neuroimage.2019.07.016. Epub 2019 Jul 8. PubMed PMID: 31295566; PubMed Central PMCID: PMC8441717.
Wykes RC, Khoo HM, Caciagli L, Blumenfeld H, Golshani P, Kapur J, Stern JM, Bernasconi A, Dedeurwaerdere S, Bernasconi N. WONOEP appraisal: Network concept from an imaging perspective. Epilepsia. 2019 Jul;60(7):1293-1305. doi: 10.1111/epi.16067. Epub 2019 Jun 9. Review. PubMed PMID: 31179547; PubMed Central PMCID: PMC6667743.
Morse E, Giblin K, Chung MH, Dohle C, Berg AT, Blumenfeld H. Historical trend toward improved long-term outcome in childhood absence epilepsy. Epilepsy Res. 2019 May;152:7-10. doi: 10.1016/j.eplepsyres.2019.02.013. Epub 2019 Feb 25. PubMed PMID: 30856420; PubMed Central PMCID: PMC6573015.
Tolchin B, Baslet G, Suzuki J, Martino S, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA. Randomized controlled trial of motivational interviewing for psychogenic nonepileptic seizures. Epilepsia. 2019 May;60(5):986-995. doi: 10.1111/epi.14728. Epub 2019 Apr 13. PubMed PMID: 30980679.
Lundstrom BN, Boly M, Duckrow R, Zaveri HP, Blumenfeld H. Slowing less than 1 Hz is decreased near the seizure onset zone. Sci Rep. 2019 Apr 17;9(1):6218. doi: 10.1038/s41598-019-42347-y. PubMed PMID: 30996228; PubMed Central PMCID: PMC6470162.
Andrews JP, Yue Z, Ryu JH, Neske G, McCormick DA, Blumenfeld H. Mechanisms of decreased cholinergic arousal in focal seizures: In vivo whole-cell recordings from the pedunculopontine tegmental nucleus. Exp Neurol. 2019 Apr;314:74-81. doi: 10.1016/j.expneurol.2018.11.008. Epub 2018 Dec 10. PubMed PMID: 30543800; PubMed Central PMCID: PMC6503533.
Andrews JP, Gummadavelli A, Farooque P, Bonito J, Arencibia C, Blumenfeld H, Spencer DD. Association of Seizure Spread With Surgical Failure in Epilepsy. JAMA Neurol. 2019 Apr 1;76(4):462-469. doi: 10.1001/jamaneurol.2018.4316. PubMed PMID: 30508033; PubMed Central PMCID: PMC6459131.
Antwi P, Atac E, Ryu JH, Arencibia CA, Tomatsu S, Saleem N, Wu J, Crowley MJ, Banz B, Vaca FE, Krestel H, Blumenfeld H. Driving status of patients with generalized spike-wave on EEG but no clinical seizures. Epilepsy Behav. 2019 Mar;92:5-13. doi: 10.1016/j.yebeh.2018.11.031. Epub 2018 Dec 21. Review. PubMed PMID: 30580109; PubMed Central PMCID: PMC6433503.
Kuo PH, Eshghi N, Tinaz S, Blumenfeld H, Louis ED, Zubal G. Optimization of Parameters for Quantitative Analysis of (123)I-Ioflupane SPECT Images for Monitoring Progression of Parkinson Disease. J Nucl Med Technol. 2019 Mar;47(1):70-74. doi: 10.2967/jnmt.118.213181. Epub 2018 Aug 23. PubMed PMID: 30139881.
Tolchin B, Dworetzky BA, Martino S, Blumenfeld H, Hirsch LJ, Baslet G. Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures. Neurology. 2019 Feb 12;92(7):e675-e679. doi: 10.1212/WNL.0000000000006848. Epub 2019 Jan 4. PubMed PMID: 30610097; PubMed Central PMCID: PMC6382361.
Herman WX, Smith RE, Kronemer SI, Watsky RE, Chen WC, Gober LM, Touloumes GJ, Khosla M, Raja A, Horien CL, Morse EC, Botta KL, Hirsch LJ, Alkawadri R, Gerrard JL, Spencer DD, Blumenfeld H. A Switch and Wave of Neuronal Activity in the Cerebral Cortex During the First Second of Conscious Perception. Cereb Cortex. 2019 Feb 1;29(2):461-474. doi: 10.1093/cercor/bhx327. PubMed PMID: 29194517; PubMed Central PMCID: PMC6319177.
Michel M, Beck D, Block N, Blumenfeld H, Brown R, Carmel D, Carrasco M, Chirimuuta M, Chun M, Cleeremans A, Dehaene S, Fleming SM, Frith C, Haggard P, He BJ, Heyes C, Goodale MA, Irvine L, Kawato M, Kentridge R, King JR, Knight RT, Kouider S, Lamme V, Lamy D, Lau H, Laureys S, LeDoux J, Lin YT, Liu K, Macknik SL, Martinez-Conde S, Mashour GA, Melloni L, Miracchi L, Mylopoulos M, Naccache L, Owen AM, Passingham RE, Pessoa L, Peters MAK, Rahnev D, Ro T, Rosenthal D, Sasaki Y, Sergent C, Solovey G, Schiff ND, Seth A, Tallon-Baudry C, Tamietto M, Tong F, van Gaal S, Vlassova A, Watanabe T, Weisberg J, Yan K, Yoshida M. Opportunities and challenges for a maturing science of consciousness. Nat Hum Behav. 2019 Feb;3(2):104-107. doi: 10.1038/s41562-019-0531-8. PubMed PMID: 30944453; PubMed Central PMCID: PMC6568255.
Benjamin CFA, Dhingra I, Li AX, Blumenfeld H, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen RA, Warfield SK, Peters JM, Reutens D, Połczyńska MM, Hirsch LJ, Spencer DD. Presurgical language fMRI: Technical practices in epilepsy surgical planning. Hum Brain Mapp. 2018 Oct;39(10):4032-4042. doi: 10.1002/hbm.24229. Epub 2018 Jul 1. PubMed PMID: 29962111; PubMed Central PMCID: PMC6175127.
Benjamin CFA, Li AX, Blumenfeld H, Constable RT, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen R, Warfield SK, Peters JM, Reutens D, Połczyńska M, Spencer DD, Hirsch LJ. Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning. Hum Brain Mapp. 2018 Jul;39(7):2777-2785. doi: 10.1002/hbm.24039. Epub 2018 Mar 12. PubMed PMID: 29528160; PubMed Central PMCID: PMC6033659.
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