PATIENT AND FAMILY INPUT TO DETERMINE EXPERIENCES AND RESEARCH INTERESTS IN PEDIATRIC PANCREATITIS: AN INSPPIRE-2 STUDY.
Pancreas.
2024 Sep 12;. doi: 10.1097/MPA.0000000000002390. [Epub ahead of print] PubMed PMID:
39259842; NIHMSID:NIHMS2009153.
Impact of Elevated Serum Triglycerides on Children with Acute Recurrent or Chronic Pancreatitis from INSPPIRE-2.
J Pediatr.
2024 Sep 12;276:114298. doi: 10.1016/j.jpeds.2024.114298. [Epub ahead of print] PubMed PMID:
39277078; NIHMSID:NIHMS2024220.
KRT17high/CXCL8+ Tumor Cells Display Both Classical and Basal Features and Regulate Myeloid Infiltration in the Pancreatic Cancer Microenvironment.
Clin Cancer Res.
2024 Jun 3;30(11):2497-2513. doi: 10.1158/1078-0432.CCR-23-1421. PubMed PMID:
37851080; PubMed Central PMCID:
PMC11024060.
Diagnostic and Prognostic Biomarkers of Chronic Pancreatitis: A Conceptual Framework Based on the PRoBE Design.
Gastroenterology.
2024 Jun;166(6):957-962.e3. doi: 10.1053/j.gastro.2024.02.030. Epub 2024 Feb 28. PubMed PMID:
38423226; PubMed Central PMCID:
PMC11102843.
MONET: a database for prediction of neoantigens derived from microsatellite loci.
Front Immunol.
2024;15:1394593. doi: 10.3389/fimmu.2024.1394593. eCollection 2024. PubMed PMID:
38835776; PubMed Central PMCID:
PMC11148240.
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype.
Cancer Res.
2024 May 15;84(10):1719-1732. doi: 10.1158/0008-5472.CAN-23-4070. PubMed PMID:
38451249; PubMed Central PMCID:
PMC11096054.
Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention.
Gastroenterology.
2024 May;166(5):787-801.e11. doi: 10.1053/j.gastro.2024.01.016. Epub 2024 Jan 18. PubMed PMID:
38244726; PubMed Central PMCID:
PMC11034773.
Circulating immune signatures in chronic pancreatitis with and without preceding acute pancreatitis: A pilot study.
Pancreatology.
2024 May;24(3):384-393. doi: 10.1016/j.pan.2024.02.012. Epub 2024 Feb 28. PubMed PMID:
38461145; PubMed Central PMCID:
PMC11023786.
The Hallmarks of Precancer.
Cancer Discov.
2024 Apr 4;14(4):683-689. doi: 10.1158/2159-8290.CD-23-1550. PubMed PMID:
38571435; PubMed Central PMCID:
PMC11170686.
Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.
Gut.
2024 Mar 7;73(4):639-648. doi: 10.1136/gutjnl-2023-331074. PubMed PMID:
38123998; PubMed Central PMCID:
PMC10958271.
Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice.
Mol Cancer Res.
2024 Mar 1;22(3):295-307. doi: 10.1158/1541-7786.MCR-23-0480. PubMed PMID:
38015750; PubMed Central PMCID:
PMC10906012.
A Small Molecule with Big Impact: MRTX1133 Targets the KRASG12D Mutation in Pancreatic Cancer.
Clin Cancer Res.
2024 Feb 16;30(4):655-662. doi: 10.1158/1078-0432.CCR-23-2098. PubMed PMID:
37831007; PubMed Central PMCID:
PMC10922474.
Circulating immune signatures across clinical stages of chronic pancreatitis: a pilot study.
Eur J Gastroenterol Hepatol.
2024 Feb 1;36(2):177-183. doi: 10.1097/MEG.0000000000002691. Epub 2023 Nov 30. PubMed PMID:
38047728; PubMed Central PMCID:
PMC10842751.
Treatment Comparisons in Adaptive Platform Trials Adjusting for Temporal Drift.
Stat Biopharm Res.
2024;16(3):361-370. doi: 10.1080/19466315.2023.2292238. Epub 2024 Jan 5. PubMed PMID:
39184873; PubMed Central PMCID:
PMC11343491.
Contributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer.
Clin Chem.
2024 Jan 4;70(1):102-115. doi: 10.1093/clinchem/hvad186. Review. PubMed PMID:
38175578.
Serum Biomarkers of Nociceptive and Neuropathic Pain in Chronic Pancreatitis.
J Pain.
2023 Dec;24(12):2199-2210. doi: 10.1016/j.jpain.2023.07.006. Epub 2023 Jul 13. PubMed PMID:
37451493; PubMed Central PMCID:
PMC10787046.
SAM: Self-adapting mixture prior to dynamically borrow information from historical data in clinical trials.
Biometrics.
2023 Dec;79(4):2857-2868. doi: 10.1111/biom.13927. Epub 2023 Sep 18. PubMed PMID:
37721513; PubMed Central PMCID:
PMC10842647.
Digitize your Biology! Modeling multicellular systems through interpretable cell behavior.
bioRxiv.
2023 Nov 5;. doi: 10.1101/2023.09.17.557982. PubMed PMID:
37745323; PubMed Central PMCID:
PMC10516032.
Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-Associated Immunity in Lynch Syndrome.
Clin Cancer Res.
2023 Nov 1;29(21):4361-4372. doi: 10.1158/1078-0432.CCR-23-0088. PubMed PMID:
37724990; PubMed Central PMCID:
PMC10618653.
Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project.
Cancer Res Commun.
2023 Oct 10;3(10):2062-2073. doi: 10.1158/2767-9764.CRC-22-0419. PubMed PMID:
37721516; PubMed Central PMCID:
PMC10563795.
BASIC: A Bayesian adaptive synthetic-control design for phase II clinical trials.
Clin Trials.
2023 Oct;20(5):486-496. doi: 10.1177/17407745231176445. Epub 2023 Jun 14. PubMed PMID:
37313712; PubMed Central PMCID:
PMC10504821.
Advances in vaccine development for cancer prevention and treatment in Lynch Syndrome.
Mol Aspects Med.
2023 Oct;93:101204. doi: 10.1016/j.mam.2023.101204. Epub 2023 Jul 19. Review. PubMed PMID:
37478804; PubMed Central PMCID:
PMC10528439.
A blood-based metabolomic signature predictive of risk for pancreatic cancer.
Cell Rep Med.
2023 Sep 19;4(9):101194. doi: 10.1016/j.xcrm.2023.101194. PubMed PMID:
37729870; PubMed Central PMCID:
PMC10518621.
KRAS(G12D) inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8(+) T cells.
Cancer Cell.
2023 Sep 11;41(9):1606-1620.e8. doi: 10.1016/j.ccell.2023.07.002. Epub 2023 Aug 24. PubMed PMID:
37625401; PubMed Central PMCID:
PMC10785700.
Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8(+) T cells.
Dev Cell.
2023 Sep 11;58(17):1562-1577.e8. doi: 10.1016/j.devcel.2023.07.025. Epub 2023 Aug 24. PubMed PMID:
37625403; PubMed Central PMCID:
PMC10810082.
Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential.
Cancer Discov.
2023 Aug 4;13(8):1844-1861. doi: 10.1158/2159-8290.CD-22-1200. PubMed PMID:
37285225; PubMed Central PMCID:
PMC10880589.
Distinct Serum Immune Profiles Define the Spectrum of Acute and Chronic Pancreatitis From the Multicenter Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies (PROCEED) Study.
Gastroenterology.
2023 Jul;165(1):173-186. doi: 10.1053/j.gastro.2023.03.236. Epub 2023 Apr 14. PubMed PMID:
37061168; PubMed Central PMCID:
PMC10330331.
Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions.
Cancer Discov.
2023 Jun 2;13(6):1324-1345. doi: 10.1158/2159-8290.CD-23-0013. PubMed PMID:
37021392; PubMed Central PMCID:
PMC10236159.
It is better to light a candle than to curse the darkness: single-cell transcriptomics sheds new light on pancreas biology and disease.
Gut.
2023 Jun;72(6):1211-1219. doi: 10.1136/gutjnl-2022-329313. Epub 2023 Mar 30. Review. PubMed PMID:
36997301; PubMed Central PMCID:
PMC10988578.
Converging on a Cure: The Roads to Predictive Immunotherapy.
Cancer Discov.
2023 May 4;13(5):1053-1057. doi: 10.1158/2159-8290.CD-23-0277. Review. PubMed PMID:
37067199; PubMed Central PMCID:
PMC10548443.
Pancreatic cancer: Advances and challenges.
Cell.
2023 Apr 13;186(8):1729-1754. doi: 10.1016/j.cell.2023.02.014. Review. PubMed PMID:
37059070; PubMed Central PMCID:
PMC10182830.
Integrated Pathologic Score Effectively Stratifies Patients With Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreaticoduodenectomy.
Am J Surg Pathol.
2023 Apr 1;47(4):421-430. doi: 10.1097/PAS.0000000000002013. Epub 2023 Feb 6. PubMed PMID:
36746143; PubMed Central PMCID:
PMC10023386.
Potential of artificial intelligence in the risk stratification for and early detection of pancreatic cancer.
Artif Intell Surg.
2023;3(1):14-26. doi: 10.20517/ais.2022.38. Epub 2023 Mar 20. PubMed PMID:
37124705; PubMed Central PMCID:
PMC10141523.
Survival improvement for patients with metastatic colorectal cancer over twenty years.
NPJ Precis Oncol.
2023 Feb 13;7(1):16. doi: 10.1038/s41698-023-00353-4. PubMed PMID:
36781990; PubMed Central PMCID:
PMC9925745.
Risk Prediction of Pancreatic Cancer in Patients With Recent-onset Hyperglycemia: A Machine-learning Approach.
J Clin Gastroenterol.
2023 Jan 1;57(1):103-110. doi: 10.1097/MCG.0000000000001710. PubMed PMID:
35470312; PubMed Central PMCID:
PMC9585151.
Nab-Paclitaxel, Capecitabine, and Radiation Therapy After Induction Chemotherapy in Treating Patients With Locally Advanced and Borderline Resectable Pancreatic Cancer: Phase 1 Trial and Imaging-based Biomarker Validation.
Int J Radiat Oncol Biol Phys.
2022 Nov 1;114(3):444-453. doi: 10.1016/j.ijrobp.2022.06.089. Epub 2022 Jul 18. PubMed PMID:
35863672.
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression.
Nat Biotechnol.
2022 Nov;40(11):1624-1633. doi: 10.1038/s41587-022-01342-x. Epub 2022 Jun 13. PubMed PMID:
35697807; PubMed Central PMCID:
PMC9646498.
T1 signal intensity ratio of the pancreas as an imaging biomarker for the staging of chronic pancreatitis.
Abdom Radiol (NY).
2022 Oct;47(10):3507-3519. doi: 10.1007/s00261-022-03611-4. Epub 2022 Jul 20. PubMed PMID:
35857066; PubMed Central PMCID:
PMC10020893.
What Can We Learn About Pancreatic Adenocarcinoma from Imaging?.
Hematol Oncol Clin North Am.
2022 Oct;36(5):911-928. doi: 10.1016/j.hoc.2022.06.003. Review. PubMed PMID:
36265990.
Mass Transport Model of Radiation Response: Calibration and Application to Chemoradiation for Pancreatic Cancer.
Int J Radiat Oncol Biol Phys.
2022 Sep 1;114(1):163-172. doi: 10.1016/j.ijrobp.2022.04.044. Epub 2022 May 26. PubMed PMID:
35643254; PubMed Central PMCID:
PMC10042520.
A Programmable In Vivo CRISPR Activation Model Elucidates the Oncogenic and Immunosuppressive Functions of MYC in Lung Adenocarcinoma.
Cancer Res.
2022 Aug 3;82(15):2761-2776. doi: 10.1158/0008-5472.CAN-21-4009. PubMed PMID:
35666804; PubMed Central PMCID:
PMC9357118.
Oncogene addiction to GNAS in GNAS(R201) mutant tumors.
Oncogene.
2022 Aug;41(35):4159-4168. doi: 10.1038/s41388-022-02388-6. Epub 2022 Jul 25. PubMed PMID:
35879396.
Novel Markers for Liquid Biopsies in Cancer Management: Circulating Platelets and Extracellular Vesicles.
Mol Cancer Ther.
2022 Jul 5;21(7):1067-1075. doi: 10.1158/1535-7163.MCT-22-0087. Review. PubMed PMID:
35545008; PubMed Central PMCID:
PMC10314793.
Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution.
Nat Commun.
2022 Jun 25;13(1):3652. doi: 10.1038/s41467-022-31376-3. PubMed PMID:
35752636; PubMed Central PMCID:
PMC9233687.
Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment.
Gastroenterology.
2022 Jun;162(7):2018-2031. doi: 10.1053/j.gastro.2022.02.024. Epub 2022 Feb 22. PubMed PMID:
35216965; PubMed Central PMCID:
PMC9278556.
Imaging of the Pancreas in New-Onset Diabetes: A Prospective Pilot Study.
Clin Transl Gastroenterol.
2022 Jun 1;13(6):e00478. doi: 10.14309/ctg.0000000000000478. PubMed PMID:
35333778; PubMed Central PMCID:
PMC9236602.
Diminished Immune Surveillance during Histologic Progression of Intraductal Papillary Mucinous Neoplasms Offers a Therapeutic Opportunity for Cancer Interception.
Clin Cancer Res.
2022 May 2;28(9):1938-1947. doi: 10.1158/1078-0432.CCR-21-2585. PubMed PMID:
35491652; PubMed Central PMCID:
PMC9069801.
Membrane-bound MMP-14 protease-activatable adeno-associated viral vectors for gene delivery to pancreatic tumors.
Gene Ther.
2022 Apr;29(3-4):138-146. doi: 10.1038/s41434-021-00255-9. Epub 2021 May 6. PubMed PMID:
33958732; PubMed Central PMCID:
PMC8571120.
Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma.
Gastroenterology.
2022 Apr;162(4):1303-1318.e18. doi: 10.1053/j.gastro.2021.12.273. Epub 2021 Dec 30. PubMed PMID:
34973294; PubMed Central PMCID:
PMC8934289.
Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.
Cancer Cell.
2022 Feb 14;40(2):153-167.e11. doi: 10.1016/j.ccell.2022.01.003. Epub 2022 Feb 3. PubMed PMID:
35120601; PubMed Central PMCID:
PMC8847236.
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