My Bibliography

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Zhang L, Nagel M, Olson WP, Chesler AT, O'Connor DH. Trigeminal innervation and tactile responses in mouse tongue. bioRxiv. 2024 May 13;. doi: 10.1101/2023.08.17.553449. PubMed PMID: 37645855; PubMed Central PMCID: PMC10462066.

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MacDonald DI, Chesler AT. Painspotting. Neuron. 2023 Sep 20;111(18):2773-2774. doi: 10.1016/j.neuron.2023.08.026. PubMed PMID: 37734319.

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Lam RM, von Buchholtz LJ, Falgairolle M, Osborne J, Frangos E, Servin-Vences MR, Nagel M, Nguyen MQ, Jayabalan M, Saade D, Patapoutian A, Bönnemann CG, Ryba NJP, Chesler AT. PIEZO2 and perineal mechanosensation are essential for sexual function. Science. 2023 Aug 25;381(6660):906-910. doi: 10.1126/science.adg0144. Epub 2023 Aug 24. PubMed PMID: 37616369; PubMed Central PMCID: PMC11418610.

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Servin-Vences MR, Lam RM, Koolen A, Wang Y, Saade DN, Loud M, Kacmaz H, Frausto S, Zhang Y, Beyder A, Marshall KL, Bönnemann CG, Chesler AT, Patapoutian A. PIEZO2 in somatosensory neurons controls gastrointestinal transit. Cell. 2023 Aug 3;186(16):3386-3399.e15. doi: 10.1016/j.cell.2023.07.006. PubMed PMID: 37541196; PubMed Central PMCID: PMC10501318.

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Kodali S, Vuong BB, Bulea TC, Chesler AT, Bönnemann CG, Okamura AM. Wearable Sensory Substitution for Proprioception via Deep Pressure. ArXiv. 2023 Jun 6;. PubMed PMID: 37502624; PubMed Central PMCID: PMC10370214.

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Enamorado M, Kulalert W, Han SJ, Rao I, Delaleu J, Link VM, Yong D, Smelkinson M, Gil L, Nakajima S, Linehan JL, Bouladoux N, Wlaschin J, Kabat J, Kamenyeva O, Deng L, Gribonika I, Chesler AT, Chiu IM, Le Pichon CE, Belkaid Y. Immunity to the microbiota promotes sensory neuron regeneration. Cell. 2023 Feb 2;186(3):607-620.e17. doi: 10.1016/j.cell.2022.12.037. Epub 2023 Jan 13. PubMed PMID: 36640762.

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Ma S, Dubin AE, Romero LO, Loud M, Salazar A, Chu S, Klier N, Masri S, Zhang Y, Wang Y, Chesler AT, Wilkinson KA, Vásquez V, Marshall KL, Patapoutian A. Excessive mechanotransduction in sensory neurons causes joint contractures. Science. 2023 Jan 13;379(6628):201-206. doi: 10.1126/science.add3598. Epub 2023 Jan 12. PubMed PMID: 36634173; PubMed Central PMCID: PMC10163824.

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Nickolls AR, O'Brien GS, Shnayder S, Zhang Y, Nagel M, Patapoutian A, Chesler AT. Reevaluation of Piezo1 as a gut RNA sensor. Elife. 2022 Nov 16;11. doi: 10.7554/eLife.83346. PubMed PMID: 36382883; PubMed Central PMCID: PMC9691018.

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Schrenk-Siemens K, Pohle J, Rostock C, Abd El Hay M, Lam RM, Szczot M, Lu S, Chesler AT, Siemens J. Human Stem Cell-Derived TRPV1-Positive Sensory Neurons: A New Tool to Study Mechanisms of Sensitization. Cells. 2022 Sep 17;11(18). doi: 10.3390/cells11182905. PubMed PMID: 36139481; PubMed Central PMCID: PMC9497105.

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Nagel M, Chesler AT. PIEZO2 ion channels in proprioception. Curr Opin Neurobiol. 2022 Aug;75:102572. doi: 10.1016/j.conb.2022.102572. Epub 2022 Jun 8. Review. PubMed PMID: 35689908.

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Szczot M, Nickolls AR, Lam RM, Chesler AT. The Form and Function of PIEZO2. Annu Rev Biochem. 2021 Jun 20;90:507-534. doi: 10.1146/annurev-biochem-081720-023244. Review. PubMed PMID: 34153212; PubMed Central PMCID: PMC8794004.

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Barik A, Sathyamurthy A, Thompson J, Seltzer M, Levine A, Chesler A. A spinoparabrachial circuit defined by Tacr1 expression drives pain. Elife. 2021 Feb 16;10. doi: 10.7554/eLife.61135. PubMed PMID: 33591273; PubMed Central PMCID: PMC7993995.

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Case LK, Liljencrantz J, Madian N, Necaise A, Tubbs J, McCall M, Bradson ML, Szczot M, Pitcher MH, Ghitani N, Frangos E, Cole J, Bharucha-Goebel D, Saade D, Ogata T, Donkervoort S, Foley AR, Bönnemann CG, Olausson H, Bushnell MC, Chesler AT. Innocuous pressure sensation requires A-type afferents but not functional ΡΙΕΖΟ2 channels in humans. Nat Commun. 2021 Jan 28;12(1):657. doi: 10.1038/s41467-021-20939-5. PubMed PMID: 33510158; PubMed Central PMCID: PMC7844252.

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von Buchholtz LJ, Ghitani N, Lam RM, Licholai JA, Chesler AT, Ryba NJP. Decoding Cellular Mechanisms for Mechanosensory Discrimination. Neuron. 2021 Jan 20;109(2):285-298.e5. doi: 10.1016/j.neuron.2020.10.028. Epub 2020 Nov 12. PubMed PMID: 33186546; PubMed Central PMCID: PMC9909446.

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Chen Z, Luo J, Li J, Kim G, Stewart A, Urban JF Jr, Huang Y, Chen S, Wu LG, Chesler A, Trinchieri G, Li W, Wu C. Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis. Immunity. 2021 Jan 12;54(1):151-163.e6. doi: 10.1016/j.immuni.2020.10.014. Epub 2020 Nov 20. PubMed PMID: 33220232; PubMed Central PMCID: PMC7856083.

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Marshall KL, Saade D, Ghitani N, Coombs AM, Szczot M, Keller J, Ogata T, Daou I, Stowers LT, Bönnemann CG, Chesler AT, Patapoutian A. PIEZO2 in sensory neurons and urothelial cells coordinates urination. Nature. 2020 Dec;588(7837):290-295. doi: 10.1038/s41586-020-2830-7. Epub 2020 Oct 14. PubMed PMID: 33057202; PubMed Central PMCID: PMC7725878.

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von Buchholtz LJ, Lam RM, Emrick JJ, Chesler AT, Ryba NJP. Assigning transcriptomic class in the trigeminal ganglion using multiplex in situ hybridization and machine learning. Pain. 2020 Sep 1;161(9):2212-2224. doi: 10.1097/j.pain.0000000000001911. PubMed PMID: 32379225; PubMed Central PMCID: PMC7606614.

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Romero LO, Caires R, Nickolls AR, Chesler AT, Cordero-Morales JF, Vásquez V. A dietary fatty acid counteracts neuronal mechanical sensitization. Nat Commun. 2020 Jun 19;11(1):2997. doi: 10.1038/s41467-020-16816-2. PubMed PMID: 32561714; PubMed Central PMCID: PMC7305179.

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Barik A, Chesler AT. Parallel Parabrachial Pathways Provide Pieces of the Pain Puzzle. Neuron. 2020 Jun 17;106(6):873-875. doi: 10.1016/j.neuron.2020.05.034. PubMed PMID: 32553201; PubMed Central PMCID: PMC8794003.

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Sathyamurthy A, Barik A, Dobrott CI, Matson KJE, Stoica S, Pursley R, Chesler AT, Levine AJ. Cerebellospinal Neurons Regulate Motor Performance and Motor Learning. Cell Rep. 2020 May 12;31(6):107595. doi: 10.1016/j.celrep.2020.107595. PubMed PMID: 32402292; PubMed Central PMCID: PMC7263484.

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Nickolls AR, Lee MM, Espinoza DF, Szczot M, Lam RM, Wang Q, Beers J, Zou J, Nguyen MQ, Solinski HJ, AlJanahi AA, Johnson KR, Ward ME, Chesler AT, Bönnemann CG. Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells. Cell Rep. 2020 Jan 21;30(3):932-946.e7. doi: 10.1016/j.celrep.2019.12.062. PubMed PMID: 31968264; PubMed Central PMCID: PMC7059559.

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Ghitani N, Chesler AT. The anatomy of the baroreceptor reflex. Cell Rep. 2019 Nov 19;29(8):2121-2122. doi: 10.1016/j.celrep.2019.11.031. PubMed PMID: 31747586; PubMed Central PMCID: PMC8794002.

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Krashes MJ, Chesler AT. Acid Tongues Cause Sour Thoughts. Cell. 2019 Oct 3;179(2):287-289. doi: 10.1016/j.cell.2019.09.013. PubMed PMID: 31585075; PubMed Central PMCID: PMC8820464.

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Nagi SS, Marshall AG, Makdani A, Jarocka E, Liljencrantz J, Ridderström M, Shaikh S, O'Neill F, Saade D, Donkervoort S, Foley AR, Minde J, Trulsson M, Cole J, Bönnemann CG, Chesler AT, Bushnell MC, McGlone F, Olausson H. An ultrafast system for signaling mechanical pain in human skin. Sci Adv. 2019 Jul;5(7):eaaw1297. doi: 10.1126/sciadv.aaw1297. eCollection 2019 Jul. PubMed PMID: 31281886; PubMed Central PMCID: PMC6609212.

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Solinski HJ, Kriegbaum MC, Tseng PY, Earnest TW, Gu X, Barik A, Chesler AT, Hoon MA. Nppb Neurons Are Sensors of Mast Cell-Induced Itch. Cell Rep. 2019 Mar 26;26(13):3561-3573.e4. doi: 10.1016/j.celrep.2019.02.089. PubMed PMID: 30917312; PubMed Central PMCID: PMC6490177.

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Barik A, Thompson JH, Seltzer M, Ghitani N, Chesler AT. A Brainstem-Spinal Circuit Controlling Nocifensive Behavior. Neuron. 2018 Dec 19;100(6):1491-1503.e3. doi: 10.1016/j.neuron.2018.10.037. Epub 2018 Nov 15. PubMed PMID: 30449655.

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Szczot M, Liljencrantz J, Ghitani N, Barik A, Lam R, Thompson JH, Bharucha-Goebel D, Saade D, Necaise A, Donkervoort S, Foley AR, Gordon T, Case L, Bushnell MC, Bönnemann CG, Chesler AT. PIEZO2 mediates injury-induced tactile pain in mice and humans. Sci Transl Med. 2018 Oct 10;10(462). doi: 10.1126/scitranslmed.aat9892. PubMed PMID: 30305456; PubMed Central PMCID: PMC6875774.

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Wlaschin JJ, Gluski JM, Nguyen E, Silberberg H, Thompson JH, Chesler AT, Le Pichon CE. Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury. Elife. 2018 Jul 3;7. doi: 10.7554/eLife.33910. PubMed PMID: 29968565; PubMed Central PMCID: PMC6029846.

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Lam RM, Chesler AT. Shear elegance: A novel screen uncovers a mechanosensitive GPCR. J Gen Physiol. 2018 Jul 2;150(7):907-910. doi: 10.1085/jgp.201812101. Epub 2018 Jun 14. PubMed PMID: 29903977; PubMed Central PMCID: PMC6028494.

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Chesler AT, Szczot M. Portraits of a pressure sensor. Elife. 2018 Jan 29;7. doi: 10.7554/eLife.34396. PubMed PMID: 29376828; PubMed Central PMCID: PMC5788499.

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Szczot M, Pogorzala LA, Solinski HJ, Young L, Yee P, Le Pichon CE, Chesler AT, Hoon MA. Cell-Type-Specific Splicing of Piezo2 Regulates Mechanotransduction. Cell Rep. 2017 Dec 5;21(10):2760-2771. doi: 10.1016/j.celrep.2017.11.035. PubMed PMID: 29212024; PubMed Central PMCID: PMC5741189.

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Ghitani N, Barik A, Szczot M, Thompson JH, Li C, Le Pichon CE, Krashes MJ, Chesler AT. Specialized Mechanosensory Nociceptors Mediating Rapid Responses to Hair Pull. Neuron. 2017 Aug 16;95(4):944-954.e4. doi: 10.1016/j.neuron.2017.07.024. PubMed PMID: 28817806; PubMed Central PMCID: PMC5599122.

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Chesler AT, Szczot M, Bharucha-Goebel D, Čeko M, Donkervoort S, Laubacher C, Hayes LH, Alter K, Zampieri C, Stanley C, Innes AM, Mah JK, Grosmann CM, Bradley N, Nguyen D, Foley AR, Le Pichon CE, Bönnemann CG. The Role of PIEZO2 in Human Mechanosensation. N Engl J Med. 2016 Oct 6;375(14):1355-1364. doi: 10.1056/NEJMoa1602812. Epub 2016 Sep 21. PubMed PMID: 27653382; PubMed Central PMCID: PMC5911918.

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Le Pichon CE, Chesler AT. The functional and anatomical dissection of somatosensory subpopulations using mouse genetics. Front Neuroanat. 2014;8:21. doi: 10.3389/fnana.2014.00021. eCollection 2014. Review. PubMed PMID: 24795573; PubMed Central PMCID: PMC4001001.

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Bohlen CJ, Chesler AT, Sharif-Naeini R, Medzihradszky KF, Zhou S, King D, Sánchez EE, Burlingame AL, Basbaum AI, Julius D. A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature. 2011 Nov 16;479(7373):410-4. doi: 10.1038/nature10607. PubMed PMID: 22094702; PubMed Central PMCID: PMC3226747.

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Cavanaugh DJ, Chesler AT, Bráz JM, Shah NM, Julius D, Basbaum AI. Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci. 2011 Jul 13;31(28):10119-27. doi: 10.1523/JNEUROSCI.1299-11.2011. PubMed PMID: 21752988; PubMed Central PMCID: PMC3147010.

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Cavanaugh DJ, Chesler AT, Jackson AC, Sigal YM, Yamanaka H, Grant R, O'Donnell D, Nicoll RA, Shah NM, Julius D, Basbaum AI. Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci. 2011 Mar 30;31(13):5067-77. doi: 10.1523/JNEUROSCI.6451-10.2011. PubMed PMID: 21451044; PubMed Central PMCID: PMC3087977.

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Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. Molecular basis of infrared detection by snakes. Nature. 2010 Apr 15;464(7291):1006-11. doi: 10.1038/nature08943. Epub 2010 Mar 14. PubMed PMID: 20228791; PubMed Central PMCID: PMC2855400.

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Zou DJ, Chesler A, Firestein S. How the olfactory bulb got its glomeruli: a just so story?. Nat Rev Neurosci. 2009 Aug;10(8):611-8. doi: 10.1038/nrn2666. Epub 2009 Jul 8. Review. PubMed PMID: 19584894.

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Le Pichon CE, Valley MT, Polymenidou M, Chesler AT, Sagdullaev BT, Aguzzi A, Firestein S. Olfactory behavior and physiology are disrupted in prion protein knockout mice. Nat Neurosci. 2009 Jan;12(1):60-9. doi: 10.1038/nn.2238. Epub 2008 Dec 21. PubMed PMID: 19098904; PubMed Central PMCID: PMC2704296.

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Chesler A, Firestein S. Neuroscience: current views on odour receptors. Nature. 2008 Apr 24;452(7190):944. doi: 10.1038/452944a. PubMed PMID: 18432233.

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Chesler AT, Le Pichon CE, Brann JH, Araneda RC, Zou DJ, Firestein S. Selective gene expression by postnatal electroporation during olfactory interneuron neurogenesis. PLoS One. 2008 Jan 30;3(1):e1517. doi: 10.1371/journal.pone.0001517. PubMed PMID: 18231603; PubMed Central PMCID: PMC2204067.

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Zou DJ, Chesler AT, Le Pichon CE, Kuznetsov A, Pei X, Hwang EL, Firestein S. Absence of adenylyl cyclase 3 perturbs peripheral olfactory projections in mice. J Neurosci. 2007 Jun 20;27(25):6675-83. doi: 10.1523/JNEUROSCI.0699-07.2007. PubMed PMID: 17581954; PubMed Central PMCID: PMC6672705.

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Peterlin Z, Chesler A, Firestein S. A painful trp can be a bonding experience. Neuron. 2007 Mar 1;53(5):635-8. doi: 10.1016/j.neuron.2007.02.011. Review. PubMed PMID: 17329204.

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Chesler AT, Zou DJ, Le Pichon CE, Peterlin ZA, Matthews GA, Pei X, Miller MC, Firestein S. A G protein/cAMP signal cascade is required for axonal convergence into olfactory glomeruli. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1039-44. doi: 10.1073/pnas.0609215104. Epub 2007 Jan 10. PubMed PMID: 17215378; PubMed Central PMCID: PMC1783360.

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Araneda RC, Peterlin Z, Zhang X, Chesler A, Firestein S. A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium. J Physiol. 2004 Mar 16;555(Pt 3):743-56. doi: 10.1113/jphysiol.2003.058040. Epub 2004 Jan 14. PubMed PMID: 14724183; PubMed Central PMCID: PMC1664868.