My Bibliography

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Boshoff HIM, Young K, Ahn YM, Yadav VD, Crowley BM, Yang L, Su J, Oh S, Arora K, Andrews J, Manikkam M, Sutphin M, Smith AJ, Weiner DM, Piazza MK, Fleegle JD, Gomez F, Dayao EK, Prideaux B, Zimmerman M, Kaya F, Sarathy J, Tan VY, Via LE, Tschirret-Guth R, Lenaerts AJ, Robertson GT, Dartois V, Olsen DB, Barry CE 3rd. Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities. ACS Infect Dis. 2024 May 10;10(5):1679-1695. doi: 10.1021/acsinfecdis.4c00025. Epub 2024 Apr 6. PubMed PMID: 38581700.

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Lyons MA, Obregon-Henao A, Ramey ME, Bauman AA, Pauly S, Rossmassler K, Reid J, Karger B, Walter ND, Robertson GT. Use of multiple pharmacodynamic measures to deconstruct the Nix-TB regimen in a short-course murine model of tuberculosis. Antimicrob Agents Chemother. 2024 May 2;68(5):e0101023. doi: 10.1128/aac.01010-23. Epub 2024 Mar 19. PubMed PMID: 38501805; PubMed Central PMCID: PMC11064538.

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Wynn EA, Dide-Agossou C, Reichlen M, Rossmassler K, Al Mubarak R, Reid JJ, Tabor ST, Born SEM, Ransom MR, Davidson RM, Walton KN, Benoit JB, Hoppers A, Loy DE, Bauman AA, Massoudi LM, Dolganov G, Strong M, Nahid P, Voskuil MI, Robertson GT, Moore CM, Walter ND. Transcriptional adaptation of Mycobacterium tuberculosis that survives prolonged multi-drug treatment in mice. mBio. 2023 Dec 19;14(6):e0236323. doi: 10.1128/mbio.02363-23. Epub 2023 Oct 31. PubMed PMID: 37905920; PubMed Central PMCID: PMC10746229.

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Walter ND, Ernest JP, Dide-Agossou C, Bauman AA, Ramey ME, Rossmassler K, Massoudi LM, Pauly S, Al Mubarak R, Voskuil MI, Kaya F, Sarathy JP, Zimmerman MD, Dartois V, Podell BK, Savic RM, Robertson GT. Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses. Antimicrob Agents Chemother. 2023 Sep 19;67(9):e0028423. doi: 10.1128/aac.00284-23. Epub 2023 Aug 11. PubMed PMID: 37565762; PubMed Central PMCID: PMC10508168.

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Parmar KR, Lukka PB, Wagh S, Temrikar ZH, Liu J, Lee RE, Braunstein M, Hickey AJ, Robertson GT, Gonzalez-Juarrero M, Edginton A, Meibohm B. Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics. Pharmaceutics. 2023 Jun 17;15(6). doi: 10.3390/pharmaceutics15061759. PubMed PMID: 37376207; PubMed Central PMCID: PMC10305115.

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Temrikar ZH, Kodidela S, Kumar S, Liu J, Robertson GT, Lee RE, Hickey AJ, Gonzalez-Juarrero M, Meibohm B. Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes. Tuberculosis (Edinb). 2023 May;140:102342. doi: 10.1016/j.tube.2023.102342. Epub 2023 Apr 20. PubMed PMID: 37120915; PubMed Central PMCID: PMC10247484.

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Reichlen MJ, Born SEM, Lyons MA, Rossmassler K, Reid J, Robertson GT, Walter ND, Voskuil MI. Standardized RS Ratio Metrics To Assess Tuberculosis Antimicrobial Efficacy and Potency. Antimicrob Agents Chemother. 2023 Jan 24;67(1):e0148322. doi: 10.1128/aac.01483-22. Epub 2023 Jan 9. PubMed PMID: 36622159; PubMed Central PMCID: PMC9872615.

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Nuermberger EL, Martínez-Martínez MS, Sanz O, Urones B, Esquivias J, Soni H, Tasneen R, Tyagi S, Li SY, Converse PJ, Boshoff HI, Robertson GT, Besra GS, Abrahams KA, Upton AM, Mdluli K, Boyle GW, Turner S, Fotouhi N, Cammack NC, Siles JM, Alonso M, Escribano J, Lelievre J, Rullas-Trincado J, Pérez-Herrán E, Bates RH, Maher-Edwards G, Barros D, Ballell L, Jiménez E. GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0013222. doi: 10.1128/aac.00132-22. Epub 2022 May 24. PubMed PMID: 35607978; PubMed Central PMCID: PMC9211396.

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Dide-Agossou C, Bauman AA, Ramey ME, Rossmassler K, Al Mubarak R, Pauly S, Voskuil MI, Garcia-Cremades M, Savic RM, Nahid P, Moore CM, Tasneen R, Nuermberger EL, Robertson GT, Walter ND. Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0231021. doi: 10.1128/aac.02310-21. Epub 2022 Mar 21. PubMed PMID: 35311519; PubMed Central PMCID: PMC9017352.

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Basarab GS, Ghorpade S, Gibhard L, Mueller R, Njoroge M, Peton N, Govender P, Massoudi LM, Robertson GT, Lenaerts AJ, Boshoff HI, Joerss D, Parish T, Durand-Reville TF, Perros M, Singh V, Chibale K. Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0219221. doi: 10.1128/aac.02192-21. Epub 2022 Mar 10. PubMed PMID: 35266826; PubMed Central PMCID: PMC9017349.

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Ma Z, He S, Yuan Y, Zhuang Z, Liu Y, Wang H, Chen J, Xu X, Ding C, Molodtsov V, Lin W, Robertson GT, Weiss WJ, Pulse M, Nguyen P, Duncan L, Doyle T, Ebright RH, Lynch AS. Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. J Med Chem. 2022 Mar 24;65(6):4481-4495. doi: 10.1021/acs.jmedchem.1c02045. Epub 2022 Feb 17. PubMed PMID: 35175750; PubMed Central PMCID: PMC8958509.

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Wilson C, Ray P, Zuccotto F, Hernandez J, Aggarwal A, Mackenzie C, Caldwell N, Taylor M, Huggett M, Mathieson M, Murugesan D, Smith A, Davis S, Cocco M, Parai MK, Acharya A, Tamaki F, Scullion P, Epemolu O, Riley J, Stojanovski L, Lopez-Román EM, Torres-Gómez PA, Toledo AM, Guijarro-Lopez L, Camino I, Engelhart CA, Schnappinger D, Massoudi LM, Lenaerts A, Robertson GT, Walpole C, Matthews D, Floyd D, Sacchettini JC, Read KD, Encinas L, Bates RH, Green SR, Wyatt PG. Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target. J Med Chem. 2022 Jan 13;65(1):409-423. doi: 10.1021/acs.jmedchem.1c01586. Epub 2021 Dec 15. PubMed PMID: 34910486; PubMed Central PMCID: PMC8762665.

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Kazakova O, Racoviceanu R, Petrova A, Mioc M, Militaru A, Udrescu L, Udrescu M, Voicu A, Cummings J, Robertson G, Ordway DJ, Slayden RA, Șoica C. New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design. Int J Mol Sci. 2021 Nov 21;22(22). doi: 10.3390/ijms222212542. PubMed PMID: 34830423; PubMed Central PMCID: PMC8621456.

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Robertson GT, Ramey ME, Massoudi LM, Carter CL, Zimmerman M, Kaya F, Graham BG, Gruppo V, Hastings C, Woolhiser LK, Scott DWL, Asay BC, Eshun-Wilson F, Maidj E, Podell BK, Vásquez JJ, Lyons MA, Dartois V, Lenaerts AJ. Comparative Analysis of Pharmacodynamics in the C3HeB/FeJ Mouse Tuberculosis Model for DprE1 Inhibitors TBA-7371, PBTZ169, and OPC-167832. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0058321. doi: 10.1128/AAC.00583-21. Epub 2021 Aug 9. PubMed PMID: 34370580; PubMed Central PMCID: PMC8522729.

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Wagh S, Rathi C, Lukka PB, Parmar K, Temrikar Z, Liu J, Scherman MS, Lee RE, Robertson GT, Lenaerts AJ, Meibohm B. Model-Based Exposure-Response Assessment for Spectinamide 1810 in a Mouse Model of Tuberculosis. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0174420. doi: 10.1128/AAC.01744-20. Epub 2021 Aug 23. PubMed PMID: 34424046; PubMed Central PMCID: PMC8522768.

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Gonzalez-Juarrero M, Lukka PB, Wagh S, Walz A, Arab J, Pearce C, Ali Z, Ryman JT, Parmar K, Temrikar Z, Munoz-Gutierrez J, Robertson GT, Liu J, Lenaerts AJ, Daley C, Lee RE, Braunstein M, Hickey AJ, Meibohm B. Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis. ACS Infect Dis. 2021 Oct 8;7(10):2850-2863. doi: 10.1021/acsinfecdis.1c00213. Epub 2021 Sep 21. PubMed PMID: 34546724; PubMed Central PMCID: PMC10226119.

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Khonde LP, Müller R, Boyle GA, Reddy V, Nchinda AT, Eyermann CJ, Fienberg S, Singh V, Myrick A, Abay E, Njoroge M, Lawrence N, Su Q, Myers TG, Boshoff HIM, Barry CE 3rd, Sirgel FA, van Helden PD, Massoudi LM, Robertson GT, Lenaerts AJ, Basarab GS, Ghorpade SR, Chibale K. 1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis. J Med Chem. 2021 Sep 9;64(17):12790-12807. doi: 10.1021/acs.jmedchem.1c00837. Epub 2021 Aug 20. PubMed PMID: 34414766; PubMed Central PMCID: PMC10500703.

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Aldridge BB, Barros-Aguirre D, Barry CE 3rd, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu XJ, Cooper CB, Dartois V, Duncan K, Fotouhi N, Gusovsky F, Hipskind PA, Kempf DJ, Lelièvre J, Lenaerts AJ, McNamara CW, Mizrahi V, Nathan C, Olsen DB, Parish T, Petrassi HM, Pym A, Rhee KY, Robertson GT, Rock JM, Rubin EJ, Russell B, Russell DG, Sacchettini JC, Schnappinger D, Schrimpf M, Upton AM, Warner P, Wyatt PG, Yuan Y. The Tuberculosis Drug Accelerator at year 10: what have we learned?. Nat Med. 2021 Aug;27(8):1333-1337. doi: 10.1038/s41591-021-01442-2. PubMed PMID: 34226736; PubMed Central PMCID: PMC10478072.

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Walter ND, Born SEM, Robertson GT, Reichlen M, Dide-Agossou C, Ektnitphong VA, Rossmassler K, Ramey ME, Bauman AA, Ozols V, Bearrows SC, Schoolnik G, Dolganov G, Garcia B, Musisi E, Worodria W, Huang L, Davis JL, Nguyen NV, Nguyen HV, Nguyen ATV, Phan H, Wilusz C, Podell BK, Sanoussi ND, de Jong BC, Merle CS, Affolabi D, McIlleron H, Garcia-Cremades M, Maidji E, Eshun-Wilson F, Aguilar-Rodriguez B, Karthikeyan D, Mdluli K, Bansbach C, Lenaerts AJ, Savic RM, Nahid P, Vásquez JJ, Voskuil MI. Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens. Nat Commun. 2021 May 18;12(1):2899. doi: 10.1038/s41467-021-22833-6. PubMed PMID: 34006838; PubMed Central PMCID: PMC8131613.

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Ray PC, Huggett M, Turner PA, Taylor M, Cleghorn LAT, Early J, Kumar A, Bonnett SA, Flint L, Joerss D, Johnson J, Korkegian A, Mullen S, Moure AL, Davis SH, Murugesan D, Mathieson M, Caldwell N, Engelhart CA, Schnappinger D, Epemolu O, Zuccotto F, Riley J, Scullion P, Stojanovski L, Massoudi L, Robertson GT, Lenaerts AJ, Freiberg G, Kempf DJ, Masquelin T, Hipskind PA, Odingo J, Read KD, Green SR, Wyatt PG, Parish T. Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth. ACS Omega. 2021 Jan 26;6(3):2284-2311. doi: 10.1021/acsomega.0c05589. eCollection 2021 Jan 26. PubMed PMID: 33521468; PubMed Central PMCID: PMC7841955.

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Akester JN, Njaria P, Nchinda A, Le Manach C, Myrick A, Singh V, Lawrence N, Njoroge M, Taylor D, Moosa A, Smith AJ, Brooks EJ, Lenaerts AJ, Robertson GT, Ioerger TR, Mueller R, Chibale K. Synthesis, Structure-Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity. ACS Infect Dis. 2020 Jul 10;6(7):1951-1964. doi: 10.1021/acsinfecdis.0c00252. Epub 2020 Jun 15. PubMed PMID: 32470286; PubMed Central PMCID: PMC7359024.

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Asay BC, Edwards BB, Andrews J, Ramey ME, Richard JD, Podell BK, Gutiérrez JFM, Frank CB, Magunda F, Robertson GT, Lyons M, Ben-Hur A, Lenaerts AJ. Digital Image Analysis of Heterogeneous Tuberculosis Pulmonary Pathology in Non-Clinical Animal Models using Deep Convolutional Neural Networks. Sci Rep. 2020 Apr 8;10(1):6047. doi: 10.1038/s41598-020-62960-6. PubMed PMID: 32269234; PubMed Central PMCID: PMC7142129.

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Michalska K, Chang C, Maltseva NI, Jedrzejczak R, Robertson GT, Gusovsky F, McCarren P, Schreiber SL, Nag PP, Joachimiak A. Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase. Protein Sci. 2020 Mar;29(3):779-788. doi: 10.1002/pro.3825. Epub 2020 Jan 20. PubMed PMID: 31930594; PubMed Central PMCID: PMC7020977.

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Robertson GT, Ektnitphong VA, Scherman MS, McNeil MB, Dennison D, Korkegian A, Smith AJ, Halladay J, Carter DS, Xia Y, Zhou Y, Choi W, Berry PW, Mao W, Hernandez V, Alley MRK, Parish T, Lenaerts AJ. Efficacy and Improved Resistance Potential of a Cofactor-Independent InhA Inhibitor of Mycobacterium tuberculosis in the C3HeB/FeJ Mouse Model. Antimicrob Agents Chemother. 2019 Apr;63(4). doi: 10.1128/AAC.02071-18. Print 2019 Apr. PubMed PMID: 30745397; PubMed Central PMCID: PMC6496157.

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Xia Y, Zhou Y, Carter DS, McNeil MB, Choi W, Halladay J, Berry PW, Mao W, Hernandez V, O'Malley T, Korkegian A, Sunde B, Flint L, Woolhiser LK, Scherman MS, Gruppo V, Hastings C, Robertson GT, Ioerger TR, Sacchettini J, Tonge PJ, Lenaerts AJ, Parish T, Alley M. Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA. Life Sci Alliance. 2018 Jun;1(3):e201800025. doi: 10.26508/lsa.201800025. eCollection 2018 Jun. PubMed PMID: 30456352; PubMed Central PMCID: PMC6238539.

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Aggarwal A, Parai MK, Shetty N, Wallis D, Woolhiser L, Hastings C, Dutta NK, Galaviz S, Dhakal RC, Shrestha R, Wakabayashi S, Walpole C, Matthews D, Floyd D, Scullion P, Riley J, Epemolu O, Norval S, Snavely T, Robertson GT, Rubin EJ, Ioerger TR, Sirgel FA, van der Merwe R, van Helden PD, Keller P, Böttger EC, Karakousis PC, Lenaerts AJ, Sacchettini JC. Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13. Cell. 2017 Jul 13;170(2):249-259.e25. doi: 10.1016/j.cell.2017.06.025. Epub 2017 Jun 29. PubMed PMID: 28669536; PubMed Central PMCID: PMC5509550.

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Robertson GT, Scherman MS, Bruhn DF, Liu J, Hastings C, McNeil MR, Butler MM, Bowlin TL, Lee RB, Lee RE, Lenaerts AJ. Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models. J Antimicrob Chemother. 2017 Mar 1;72(3):770-777. doi: 10.1093/jac/dkw467. PubMed PMID: 27999020; PubMed Central PMCID: PMC5400088.

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Liu J, Bruhn DF, Lee RB, Zheng Z, Janusic T, Scherbakov D, Scherman MS, Boshoff HI, Das S, Rakesh, Waidyarachchi SL, Brewer TA, Gracia B, Yang L, Bollinger J, Robertson GT, Meibohm B, Lenaerts AJ, Ainsa J, Böttger EC, Lee RE. Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions. ACS Infect Dis. 2017 Jan 13;3(1):72-88. doi: 10.1021/acsinfecdis.6b00158. Epub 2016 Nov 11. PubMed PMID: 28081607; PubMed Central PMCID: PMC5493200.

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Silvers MA, Robertson GT, Taylor CM, Waldrop GL. Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. J Med Chem. 2014 Nov 13;57(21):8947-59. doi: 10.1021/jm501082n. Epub 2014 Oct 15. PubMed PMID: 25280369.

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Robertson GT, Case ED, Dobbs N, Ingle C, Balaban M, Celli J, Norgard MV. FTT0831c/FTL_0325 contributes to Francisella tularensis cell division, maintenance of cell shape, and structural integrity. Infect Immun. 2014 Jul;82(7):2935-48. doi: 10.1128/IAI.00102-14. Epub 2014 Apr 28. PubMed PMID: 24778115; PubMed Central PMCID: PMC4097634.

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Robertson GT, Child R, Ingle C, Celli J, Norgard MV. IglE is an outer membrane-associated lipoprotein essential for intracellular survival and murine virulence of type A Francisella tularensis. Infect Immun. 2013 Nov;81(11):4026-40. doi: 10.1128/IAI.00595-13. Epub 2013 Aug 19. PubMed PMID: 23959721; PubMed Central PMCID: PMC3811846.

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Huntley JF, Robertson GT, Norgard MV. Method for the isolation of Francisella tularensis outer membranes. J Vis Exp. 2010 Jun 29;(40). doi: 10.3791/2044. PubMed PMID: 20613713; PubMed Central PMCID: PMC3156061.

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Robertson GT, Bonventre EJ, Doyle TB, Du Q, Duncan L, Morris TW, Roche ED, Yan D, Lynch AS. In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: studies of the mode of action in Staphylococcus aureus. Antimicrob Agents Chemother. 2008 Jul;52(7):2313-23. doi: 10.1128/AAC.01649-07. Epub 2008 Apr 28. PubMed PMID: 18443108; PubMed Central PMCID: PMC2443886.

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Robertson GT, Bonventre EJ, Doyle TB, Du Q, Duncan L, Morris TW, Roche ED, Yan D, Lynch AS. In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: microbiology profiling studies with staphylococci and streptococci. Antimicrob Agents Chemother. 2008 Jul;52(7):2324-34. doi: 10.1128/AAC.01651-07. Epub 2008 Apr 28. PubMed PMID: 18443106; PubMed Central PMCID: PMC2443883.

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Lynch AS, Robertson GT. Bacterial and fungal biofilm infections. Annu Rev Med. 2008;59:415-28. doi: 10.1146/annurev.med.59.110106.132000. Review. PubMed PMID: 17937586.

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Robertson GT, Doyle TB, Du Q, Duncan L, Mdluli KE, Lynch AS. A Novel indole compound that inhibits Pseudomonas aeruginosa growth by targeting MreB is a substrate for MexAB-OprM. J Bacteriol. 2007 Oct;189(19):6870-81. doi: 10.1128/JB.00805-07. Epub 2007 Jul 20. PubMed PMID: 17644596; PubMed Central PMCID: PMC2045200.

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Combrink KD, Denton DA, Harran S, Ma Z, Chapo K, Yan D, Bonventre E, Roche ED, Doyle TB, Robertson GT, Lynch AS. New C25 carbamate rifamycin derivatives are resistant to inactivation by ADP-ribosyl transferases. Bioorg Med Chem Lett. 2007 Jan 15;17(2):522-6. doi: 10.1016/j.bmcl.2006.10.016. Epub 2006 Oct 12. PubMed PMID: 17070048.

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Robertson GT, Doyle TB, Lynch AS. Use of an efflux-deficient streptococcus pneumoniae strain panel to identify ABC-class multidrug transporters involved in intrinsic resistance to antimicrobial agents. Antimicrob Agents Chemother. 2005 Nov;49(11):4781-3. doi: 10.1128/AAC.49.11.4781-4783.2005. PubMed PMID: 16251330; PubMed Central PMCID: PMC1280156.

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Valderas MW, Alcantara RB, Baumgartner JE, Bellaire BH, Robertson GT, Ng WL, Richardson JM, Winkler ME, Roop RM 2nd. Role of HdeA in acid resistance and virulence in Brucella abortus 2308. Vet Microbiol. 2005 May 20;107(3-4):307-12. doi: 10.1016/j.vetmic.2005.01.018. PubMed PMID: 15863292.

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Gee JM, Valderas MW, Kovach ME, Grippe VK, Robertson GT, Ng WL, Richardson JM, Winkler ME, Roop RM 2nd. The Brucella abortus Cu,Zn superoxide dismutase is required for optimal resistance to oxidative killing by murine macrophages and wild-type virulence in experimentally infected mice. Infect Immun. 2005 May;73(5):2873-80. doi: 10.1128/IAI.73.5.2873-2880.2005. PubMed PMID: 15845493; PubMed Central PMCID: PMC1087332.

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Ng WL, Robertson GT, Kazmierczak KM, Zhao J, Gilmour R, Winkler ME. Constitutive expression of PcsB suppresses the requirement for the essential VicR (YycF) response regulator in Streptococcus pneumoniae R6. Mol Microbiol. 2003 Dec;50(5):1647-63. doi: 10.1046/j.1365-2958.2003.03806.x. PubMed PMID: 14651645.

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Roop RM 2nd, Gee JM, Robertson GT, Richardson JM, Ng WL, Winkler ME. Brucella stationary-phase gene expression and virulence. Annu Rev Microbiol. 2003;57:57-76. doi: 10.1146/annurev.micro.57.030502.090803. Epub 2003 May 1. Review. PubMed PMID: 12730323.

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Robertson GT, Ng WL, Gilmour R, Winkler ME. Essentiality of clpX, but not clpP, clpL, clpC, or clpE, in Streptococcus pneumoniae R6. J Bacteriol. 2003 May;185(9):2961-6. doi: 10.1128/JB.185.9.2961-2966.2003. PubMed PMID: 12700276; PubMed Central PMCID: PMC154392.

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Fernandez-Prada CM, Zelazowska EB, Nikolich M, Hadfield TL, Roop RM 2nd, Robertson GL, Hoover DL. Interactions between Brucella melitensis and human phagocytes: bacterial surface O-Polysaccharide inhibits phagocytosis, bacterial killing, and subsequent host cell apoptosis. Infect Immun. 2003 Apr;71(4):2110-9. doi: 10.1128/IAI.71.4.2110-2119.2003. PubMed PMID: 12654833; PubMed Central PMCID: PMC152029.

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Ng WL, Kazmierczak KM, Robertson GT, Gilmour R, Winkler ME. Transcriptional regulation and signature patterns revealed by microarray analyses of Streptococcus pneumoniae R6 challenged with sublethal concentrations of translation inhibitors. J Bacteriol. 2003 Jan;185(1):359-70. doi: 10.1128/JB.185.1.359-370.2003. PubMed PMID: 12486074; PubMed Central PMCID: PMC141824.

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Roop RM 2nd, Robertson GT, Ferguson GP, Milford LE, Winkler ME, Walker GC. Seeking a niche: putative contributions of the hfq and bacA gene products to the successful adaptation of the brucellae to their intracellular home. Vet Microbiol. 2002 Dec 20;90(1-4):349-63. doi: 10.1016/s0378-1135(02)00220-1. Review. PubMed PMID: 12414155.

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Robertson GT, Zhao J, Desai BV, Coleman WH, Nicas TI, Gilmour R, Grinius L, Morrison DA, Winkler ME. Vancomycin tolerance induced by erythromycin but not by loss of vncRS, vex3, or pep27 function in Streptococcus pneumoniae. J Bacteriol. 2002 Dec;184(24):6987-7000. doi: 10.1128/JB.184.24.6987-7000.2002. PubMed PMID: 12446649; PubMed Central PMCID: PMC135460.

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Murphy E, Robertson GT, Parent M, Hagius SD, Roop RM 2nd, Elzer PH, Baldwin CL. Major histocompatibility complex class I and II expression on macrophages containing a virulent strain of Brucella abortus measured using green fluorescent protein-expressing brucellae and flow cytometry. FEMS Immunol Med Microbiol. 2002 Jul 12;33(3):191-200. doi: 10.1111/j.1574-695X.2002.tb00590.x. PubMed PMID: 12110481.

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Robertson GT, Ng WL, Foley J, Gilmour R, Winkler ME. Global transcriptional analysis of clpP mutations of type 2 Streptococcus pneumoniae and their effects on physiology and virulence. J Bacteriol. 2002 Jul;184(13):3508-20. doi: 10.1128/JB.184.13.3508-3520.2002. PubMed PMID: 12057945; PubMed Central PMCID: PMC135132.

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Glass JI, Belanger AE, Robertson GT. Streptococcus pneumoniae as a genomics platform for broad-spectrum antibiotic discovery. Curr Opin Microbiol. 2002 Jun;5(3):338-42. doi: 10.1016/s0959-4388(02)90328-4. Review. PubMed PMID: 12057692.