My Bibliography

select

Pillsbury CE, Dougan J, Rabe JL, Fonseca JA, Zhou C, Evans AN, Abukharma H, Ichoku O, Gonzalez-Flamenco G, Park SI, Aljudi A, DeRyckere D, Castellino SM, Rafiq S, Langermann S, Liu LN, Henry CJ, Porter CC. Siglec-15 Promotes Evasion of Adaptive Immunity in B-cell Acute Lymphoblastic Leukemia. Cancer Res Commun. 2023 Jul;3(7):1248-1259. doi: 10.1158/2767-9764.CRC-23-0056. eCollection 2023 Jul. PubMed PMID: 37465593; PubMed Central PMCID: PMC10351425.

select

Hossian AKMN, Hackett CS, Brentjens RJ, Rafiq S. Multipurposing CARs: Same engine, different vehicles. Mol Ther. 2022 Apr 6;30(4):1381-1395. doi: 10.1016/j.ymthe.2022.02.012. Epub 2022 Feb 11. Review. PubMed PMID: 35151842; PubMed Central PMCID: PMC9077369.

select

Verma A, Rafiq S. Chimeric Antigen Receptor (CAR) T Cell Therapy for Glioblastoma. Cancer Treat Res. 2022;183:161-184. doi: 10.1007/978-3-030-96376-7_5. Review. PubMed PMID: 35551659.

select

Alspach E, Chow RD, Demehri S, Guerriero JL, Gujar S, Hartmann FJ, Helmink BA, Hudson WH, Ho WJ, Ma L, Maier BB, Maltez VI, Miller BC, Moran AE, Parry EM, Pillai PS, Rafiq S, Reina-Campos M, Rosato PC, Rudqvist NP, Ruhland MK, Sagiv-Barfi I, Sahu AD, Samstein RM, Schürch CM, Sen DR, Thommen DS, Wolf Y, Zappasodi R. Supporting the Next Generation of Scientists to Lead Cancer Immunology Research. Cancer Immunol Res. 2021 Nov;9(11):1245-1251. doi: 10.1158/2326-6066.CIR-21-0519. Epub 2021 Sep 20. PubMed PMID: 34544686; PubMed Central PMCID: PMC9644410.

select

Uricoli B, Birnbaum LA, Do P, Kelvin JM, Jain J, Costanza E, Chyong A, Porter CC, Rafiq S, Dreaden EC. Engineered Cytokines for Cancer and Autoimmune Disease Immunotherapy. Adv Healthc Mater. 2021 Aug;10(15):e2002214. doi: 10.1002/adhm.202002214. Epub 2021 Mar 9. Review. PubMed PMID: 33690997; PubMed Central PMCID: PMC8651077.

select

Evans AN, Lin HK, Hossian AKMN, Rafiq S. Using Adoptive Cellular Therapy for Localized Protein Secretion. Cancer J. 2021 Mar-Apr 01;27(2):159-167. doi: 10.1097/PPO.0000000000000510. Review. PubMed PMID: 33750076; PubMed Central PMCID: PMC7988838.

select

Song M, Yeku OO, Rafiq S, Purdon T, Dong X, Zhu L, Zhang T, Wang H, Yu Z, Mai J, Shen H, Nixon B, Li M, Brentjens RJ, Ma X. Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages. Nat Commun. 2020 Dec 8;11(1):6298. doi: 10.1038/s41467-020-20140-0. PubMed PMID: 33293516; PubMed Central PMCID: PMC7722725.

select

Wijewarnasuriya D, Bebernitz C, Lopez AV, Rafiq S, Brentjens RJ. Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells. Cancer Immunol Res. 2020 Jun;8(6):732-742. doi: 10.1158/2326-6066.CIR-19-0908. Epub 2020 Mar 25. PubMed PMID: 32213625; PubMed Central PMCID: PMC7269815.

select

Drakes DJ, Rafiq S, Purdon TJ, Lopez AV, Chandran SS, Klebanoff CA, Brentjens RJ. Optimization of T-cell Receptor-Modified T Cells for Cancer Therapy. Cancer Immunol Res. 2020 Jun;8(6):743-755. doi: 10.1158/2326-6066.CIR-19-0910. Epub 2020 Mar 24. PubMed PMID: 32209638; PubMed Central PMCID: PMC7269835.

select

Rafiq S, Hackett CS, Brentjens RJ. Engineering strategies to overcome the current roadblocks in CAR T cell therapy. Nat Rev Clin Oncol. 2020 Mar;17(3):147-167. doi: 10.1038/s41571-019-0297-y. Epub 2019 Dec 17. Review. PubMed PMID: 31848460; PubMed Central PMCID: PMC7223338.

select

Jin CH, Xia J, Rafiq S, Huang X, Hu Z, Zhou X, Brentjens RJ, Yang YG. Modeling anti-CD19 CAR T cell therapy in humanized mice with human immunity and autologous leukemia. EBioMedicine. 2019 Jan;39:173-181. doi: 10.1016/j.ebiom.2018.12.013. Epub 2018 Dec 20. PubMed PMID: 30579863; PubMed Central PMCID: PMC6354733.

select

Rafiq S, Brentjens RJ. Tumors evading CARs-the chase is on. Nat Med. 2018 Oct;24(10):1492-1493. doi: 10.1038/s41591-018-0212-6. PubMed PMID: 30297897.

select

Rafiq S, Yeku OO, Jackson HJ, Purdon TJ, van Leeuwen DG, Drakes DJ, Song M, Miele MM, Li Z, Wang P, Yan S, Xiang J, Ma X, Seshan VE, Hendrickson RC, Liu C, Brentjens RJ. Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo. Nat Biotechnol. 2018 Oct;36(9):847-856. doi: 10.1038/nbt.4195. Epub 2018 Aug 13. PubMed PMID: 30102295; PubMed Central PMCID: PMC6126939.

select

Rafiq S, Purdon TJ, Daniyan AF, Koneru M, Dao T, Liu C, Scheinberg DA, Brentjens RJ. Optimized T-cell receptor-mimic chimeric antigen receptor T cells directed toward the intracellular Wilms Tumor 1 antigen. Leukemia. 2017 Aug;31(8):1788-1797. doi: 10.1038/leu.2016.373. Epub 2016 Dec 7. PubMed PMID: 27924074; PubMed Central PMCID: PMC5495623.

select

Jackson HJ, Rafiq S, Brentjens RJ. Driving CAR T-cells forward. Nat Rev Clin Oncol. 2016 Jun;13(6):370-83. doi: 10.1038/nrclinonc.2016.36. Epub 2016 Mar 22. Review. PubMed PMID: 27000958; PubMed Central PMCID: PMC5529102.

select

Pegram HJ, Smith EL, Rafiq S, Brentjens RJ. CAR therapy for hematological cancers: can success seen in the treatment of B-cell acute lymphoblastic leukemia be applied to other hematological malignancies?. Immunotherapy. 2015;7(5):545-61. doi: 10.2217/imt.15.6. Review. PubMed PMID: 26065479; PubMed Central PMCID: PMC5238709.

select

Cheney CM, Stephens DM, Mo X, Rafiq S, Butchar J, Flynn JM, Jones JA, Maddocks K, O'Reilly A, Ramachandran A, Tridandapani S, Muthusamy N, Byrd JC. Ocaratuzumab, an Fc-engineered antibody demonstrates enhanced antibody-dependent cell-mediated cytotoxicity in chronic lymphocytic leukemia. MAbs. 2014 May-Jun;6(3):749-55. doi: 10.4161/mabs.28282. Epub 2014 Mar 4. PubMed PMID: 24594909; PubMed Central PMCID: PMC4011919.

select

Kohrt HE, Sagiv-Barfi I, Rafiq S, Herman SE, Butchar JP, Cheney C, Zhang X, Buggy JJ, Muthusamy N, Levy R, Johnson AJ, Byrd JC. Ibrutinib antagonizes rituximab-dependent NK cell-mediated cytotoxicity. Blood. 2014 Mar 20;123(12):1957-60. doi: 10.1182/blood-2014-01-547869. PubMed PMID: 24652965; PubMed Central PMCID: PMC3962169.

select

Rafiq S, Siadak A, Butchar JP, Cheney C, Lozanski G, Jacob NK, Lapalombella R, McGourty J, Moledor M, Lowe R, Setter B, Jones J, Flynn JM, Andritsos L, Devine S, Mo X, Jarjoura D, Tridandapani S, Algate P, Byrd JC, Muthusamy N. Glycovariant anti-CD37 monospecific protein therapeutic exhibits enhanced effector cell-mediated cytotoxicity against chronic and acute B cell malignancies. MAbs. 2013 Sep-Oct;5(5):723-35. doi: 10.4161/mabs.25282. Epub 2013 Jun 7. PubMed PMID: 23883821; PubMed Central PMCID: PMC3851225.

select

Rafiq S, Butchar JP, Cheney C, Mo X, Trotta R, Caligiuri M, Jarjoura D, Tridandapani S, Muthusamy N, Byrd JC. Comparative assessment of clinically utilized CD20-directed antibodies in chronic lymphocytic leukemia cells reveals divergent NK cell, monocyte, and macrophage properties. J Immunol. 2013 Mar 15;190(6):2702-11. doi: 10.4049/jimmunol.1202588. Epub 2013 Feb 15. PubMed PMID: 23418626; PubMed Central PMCID: PMC3631574.

select

Rafiq S, Cheney C, Mo X, Jarjoura D, Muthusamy N, Byrd JC. XmAb-5574 antibody demonstrates superior antibody-dependent cellular cytotoxicity as compared with CD52- and CD20-targeted antibodies in adult acute lymphoblastic leukemia cells. Leukemia. 2012 Jul;26(7):1720-2. doi: 10.1038/leu.2012.40. Epub 2012 Feb 15. PubMed PMID: 22333878; PubMed Central PMCID: PMC3676652.

select

Lapalombella R, Yeh YY, Wang L, Ramanunni A, Rafiq S, Jha S, Staubli J, Lucas DM, Mani R, Herman SEM, Johnson AJ, Lozanski A, Andritsos L, Jones J, Flynn JM, Lannutti B, Thompson P, Algate P, Stromatt S, Jarjoura D, Mo X, Wang D, Chen CS, Lozanski G, Heerema NA, Tridandapani S, Freitas MA, Muthusamy N, Byrd JC. Tetraspanin CD37 directly mediates transduction of survival and apoptotic signals. Cancer Cell. 2012 May 15;21(5):694-708. doi: 10.1016/j.ccr.2012.03.040. PubMed PMID: 22624718; PubMed Central PMCID: PMC3360882.

select

Leshchenko VV, Kuo PY, Shaknovich R, Yang DT, Gellen T, Petrich A, Yu Y, Remache Y, Weniger MA, Rafiq S, Suh KS, Goy A, Wilson W, Verma A, Braunschweig I, Muthusamy N, Kahl BS, Byrd JC, Wiestner A, Melnick A, Parekh S. Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood. 2010 Aug 19;116(7):1025-34. doi: 10.1182/blood-2009-12-257485. Epub 2010 Apr 28. PubMed PMID: 20427703; PubMed Central PMCID: PMC2938124.

select

Raffaniello R, Fedorova D, Ip D, Rafiq S. Hsp90 Co-localizes with Rab-GDI-1 and regulates agonist-induced amylase release in AR42J cells. Cell Physiol Biochem. 2009;24(5-6):369-78. doi: 10.1159/000257429. Epub 2009 Nov 4. PubMed PMID: 19910677; PubMed Central PMCID: PMC3711583.

select

Montero E, Rafiq S, Heck S, Lobo CA. Inhibition of human erythrocyte invasion by Babesia divergens using serine protease inhibitors. Mol Biochem Parasitol. 2007 May;153(1):80-4. doi: 10.1016/j.molbiopara.2007.01.014. Epub 2007 Jan 26. PubMed PMID: 17320984.