Thromboembolism in Patients with Metastatic Urothelial Cancer Treated with Immune Checkpoint Inhibitors.
Target Oncol.
2022 Sep;17(5):563-569. doi: 10.1007/s11523-022-00905-x. Epub 2022 Aug 20. PubMed PMID:
35986816; NIHMSID:NIHMS1832555.
Old is new again: emergence of thromboembolic complications in cancer patients on immunotherapy.
Thromb Res.
2022 May;213(Suppl 1):S51-S57. doi: 10.1016/j.thromres.2022.01.006. Epub 2022 May 26. Review. PubMed PMID:
36061419; PubMed Central PMCID:
PMC9435305.
Biomarker signatures in cancer patients with and without venous thromboembolism events: a substudy of CASSINI.
Blood Adv.
2022 Feb 22;6(4):1212-1221. doi: 10.1182/bloodadvances.2021005710. PubMed PMID:
34807979; PubMed Central PMCID:
PMC8864658.
Increased Incidence of Venous Thromboembolism with Cancer Immunotherapy.
Med.
2021 Apr 9;2(4):423-434. doi: 10.1016/j.medj.2021.02.002. Epub 2021 Mar 12. PubMed PMID:
34036293; PubMed Central PMCID:
PMC8143033.
Mediators of Inflammation-Driven Expansion, Trafficking, and Function of Tumor-Infiltrating MDSCs.
Cancer Immunol Res.
2019 Oct;7(10):1687-1699. doi: 10.1158/2326-6066.CIR-18-0578. Epub 2019 Aug 22. PubMed PMID:
31439615; PubMed Central PMCID:
PMC6774821.
Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma.
Neuro Oncol.
2019 Mar 18;21(4):537-546. doi: 10.1093/neuonc/noy202. PubMed PMID:
30883662; PubMed Central PMCID:
PMC6422437.
Ex vivo conditioning with IL-12 protects tumor-infiltrating CD8(+) T cells from negative regulation by local IFN-γ.
Cancer Immunol Immunother.
2019 Mar;68(3):395-405. doi: 10.1007/s00262-018-2280-3. Epub 2018 Dec 14. PubMed PMID:
30552459; PubMed Central PMCID:
PMC6428620.
Immune-Checkpoint Blockade Opposes CD8(+) T-cell Suppression in Human and Murine Cancer.
Cancer Immunol Res.
2019 Mar;7(3):510-525. doi: 10.1158/2326-6066.CIR-18-0054. Epub 2019 Feb 6. PubMed PMID:
30728151; PubMed Central PMCID:
PMC6476322.
Decreased T-Cell Programmed Death Receptor-1 Expression in Pregnancy-Associated Melanoma.
Am J Dermatopathol.
2019 Mar;41(3):180-187. doi: 10.1097/DAD.0000000000001286. PubMed PMID:
30308543.
Combination PD-1 blockade and irradiation of brain metastasis induces an effective abscopal effect in melanoma.
Oncoimmunology.
2019;8(1):e1507669. doi: 10.1080/2162402X.2018.1507669. eCollection 2019. PubMed PMID:
30546944; PubMed Central PMCID:
PMC6287893.
Immunological Correlates of Response to Immune Checkpoint Inhibitors in Metastatic Urothelial Carcinoma.
Target Oncol.
2018 Oct;13(5):599-609. doi: 10.1007/s11523-018-0595-9. PubMed PMID:
30267200.
Myeloid-derived suppressors cells (MDSC) correlate with clinicopathologic factors and pathologic complete response (pCR) in patients with urothelial carcinoma (UC) undergoing cystectomy.
Urol Oncol.
2018 Sep;36(9):405-412. doi: 10.1016/j.urolonc.2018.02.018. Epub 2018 Mar 30. Review. PubMed PMID:
29606341.
Evaluation of T cell infiltration in matched biopsy and nephrectomy samples in renal cell carcinoma.
Medicine (Baltimore).
2018 Sep;97(37):e12344. doi: 10.1097/MD.0000000000012344. PubMed PMID:
30212988; PubMed Central PMCID:
PMC6156035.
Challenges faced when identifying patients for combination immunotherapy.
Future Oncol.
2017 Aug;13(18):1607-1618. doi: 10.2217/fon-2017-0218. Epub 2017 Aug 24. Review. PubMed PMID:
28835114.
Tumor-derived exosomes induce CD8(+) T cell suppressors.
J Immunother Cancer.
2017 Aug 15;5(1):65. doi: 10.1186/s40425-017-0269-7. PubMed PMID:
28806909; PubMed Central PMCID:
PMC5556362.
Myeloid-Derived Suppressor Cell Subset Accumulation in Renal Cell Carcinoma Parenchyma Is Associated with Intratumoral Expression of IL1β, IL8, CXCL5, and Mip-1α.
Clin Cancer Res.
2017 May 1;23(9):2346-2355. doi: 10.1158/1078-0432.CCR-15-1823. Epub 2016 Oct 31. PubMed PMID:
27799249; PubMed Central PMCID:
PMC5411325.
MEK inhibition abrogates sunitinib resistance in a renal cell carcinoma patient-derived xenograft model.
Br J Cancer.
2016 Oct 11;115(8):920-928. doi: 10.1038/bjc.2016.263. Epub 2016 Aug 25. PubMed PMID:
27560553; PubMed Central PMCID:
PMC5061902.
Myeloid-derived suppressor cells in cancer: therapeutic, predictive, and prognostic implications.
Semin Oncol.
2014 Apr;41(2):174-84. doi: 10.1053/j.seminoncol.2014.02.003. Epub 2014 Feb 14. Review. PubMed PMID:
24787291; PubMed Central PMCID:
PMC4008844.
Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: role of CD62L.
Immunol Res.
2013 Dec;57(1-3):23-33. doi: 10.1007/s12026-013-8456-1. PubMed PMID:
24218360; NIHMSID:NIHMS705846.
Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors.
J Transl Med.
2013 Mar 8;11:62. doi: 10.1186/1479-5876-11-62. PubMed PMID:
23497415; PubMed Central PMCID:
PMC3599587.
A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice.
J Immunol.
2012 Aug 15;189(4):1627-38. doi: 10.4049/jimmunol.1103271. Epub 2012 Jul 13. PubMed PMID:
22798675; PubMed Central PMCID:
PMC3674773.
The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide-induced hematopoietic and immune suppression by reducing oxidative stress.
Free Radic Biol Med.
2012 May 1;52(9):1560-8. doi: 10.1016/j.freeradbiomed.2012.02.007. Epub 2012 Feb 15. PubMed PMID:
22343421; PubMed Central PMCID:
PMC3341494.
Myeloid-derived suppressor cells in cancer patients: a clinical perspective.
J Immunother.
2012 Feb-Mar;35(2):107-15. doi: 10.1097/CJI.0b013e318242169f. Review. PubMed PMID:
22306898.
Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer.
Breast Cancer Res Treat.
2012 Feb;132(1):215-23. doi: 10.1007/s10549-011-1889-0. Epub 2011 Dec 3. PubMed PMID:
22138748; PubMed Central PMCID:
PMC3697917.
Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory.
Am J Cancer Res.
2011 Aug 30;1(7):882-96. PubMed PMID:
21915391; PubMed Central PMCID:
PMC3170749.
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.
Blood.
2011 Aug 25;118(8):2254-65. doi: 10.1182/blood-2010-12-325753. Epub 2011 Jul 6. PubMed PMID:
21734236; PubMed Central PMCID:
PMC3709641.
Nab-paclitaxel in the treatment of metastatic breast cancer: a comprehensive review.
Expert Rev Clin Pharmacol.
2011 May;4(3):329-34. doi: 10.1586/ecp.11.7. Review. PubMed PMID:
22114779.
Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis.
J Clin Invest.
2010 May;120(5):1515-23. doi: 10.1172/JCI40802. Epub 2010 Apr 12. PubMed PMID:
20389021; PubMed Central PMCID:
PMC2860925.
Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.
J Immunol.
2010 Feb 15;184(4):1737-47. doi: 10.4049/jimmunol.0902309. Epub 2010 Jan 18. PubMed PMID:
20083664; PubMed Central PMCID:
PMC3066076.
Cytokines and angiogenic factors in patients with metastatic renal cell carcinoma treated with interferon-alpha: association of pretreatment serum levels with survival.
Ann Oncol.
2009 Oct;20(10):1682-7. doi: 10.1093/annonc/mdp054. Epub 2009 Jun 18. PubMed PMID:
19541791; PubMed Central PMCID:
PMC4542573.
Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C).
J Immunol.
2009 Feb 15;182(4):2030-40. doi: 10.4049/jimmunol.0801829. PubMed PMID:
19201856; PubMed Central PMCID:
PMC3066095.
The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into naïve recipient mice.
Vaccine.
2009 Jan 22;27(4):549-57. doi: 10.1016/j.vaccine.2008.11.013. Epub 2008 Nov 21. PubMed PMID:
19027047; PubMed Central PMCID:
PMC3072892.
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy.
Cancer Immunol Immunother.
2009 Jan;58(1):49-59. doi: 10.1007/s00262-008-0523-4. Epub 2008 Apr 30. PubMed PMID:
18446337; PubMed Central PMCID:
PMC3401888.
Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model.
Cancer Immunol Immunother.
2008 Apr;57(4):563-72. doi: 10.1007/s00262-007-0394-0. Epub 2007 Aug 28. PubMed PMID:
17726606; PubMed Central PMCID:
PMC3406410.
Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer.
Cancer Biol Ther.
2006 Nov;5(11):1494-501. doi: 10.4161/cbt.5.11.3299. Epub 2006 Nov 19. PubMed PMID:
17369752.
PI3-K/Akt-mediated anoikis resistance of human osteosarcoma cells requires Src activation.
Eur J Cancer.
2006 Jul;42(10):1491-500. doi: 10.1016/j.ejca.2006.03.007. Epub 2006 Jun 8. PubMed PMID:
16759849.
Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents.
BMC Cancer.
2005 Apr 13;5:39. doi: 10.1186/1471-2407-5-39. PubMed PMID:
15829011; PubMed Central PMCID:
PMC1090563.
Acquisition of anoikis resistance in human osteosarcoma cells.
Eur J Cancer.
2003 Nov;39(16):2395-402. doi: 10.1016/s0959-8049(03)00575-6. PubMed PMID:
14556933.
Identification of CD8 T-lymphocyte epitopes in OmpB of Rickettsia conorii.
Infect Immun.
2003 Jul;71(7):3920-6. doi: 10.1128/IAI.71.7.3920-3926.2003. PubMed PMID:
12819078; PubMed Central PMCID:
PMC161984.
Langerhans cell histiocytosis of the female genital tract: a literature review.
Int J Gynecol Cancer.
2003 May-Jun;13(3):381-8. doi: 10.1046/j.1525-1438.2003.13204.x. Review. PubMed PMID:
12801274.
Alpha 4 integrin increases anoikis of human osteosarcoma cells.
J Cell Biochem.
2003 Apr 1;88(5):1038-47. doi: 10.1002/jcb.10465. PubMed PMID:
12616540.
Immunization with a portion of rickettsial outer membrane protein A stimulates protective immunity against spotted fever rickettsiosis.
Vaccine.
2001 Dec 12;20(5-6):979-88. doi: 10.1016/s0264-410x(01)00377-2. PubMed PMID:
11738766.
Identification of protective components of two major outer membrane proteins of spotted fever group Rickettsiae.
Am J Trop Med Hyg.
2001 Oct;65(4):371-8. doi: 10.4269/ajtmh.2001.65.371. PubMed PMID:
11693887.
Molecular cloning and characterization of the 120-kilodalton protein gene of Ehrlichia canis and application of the recombinant 120-kilodalton protein for serodiagnosis of canine ehrlichiosis.
J Clin Microbiol.
2000 Jan;38(1):369-74. doi: 10.1128/JCM.38.1.369-374.2000. PubMed PMID:
10618118; PubMed Central PMCID:
PMC88726.
What would you like to do?