My Bibliography

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Burger S, Stenger T, Pierson M, Sridhar A, Huggins MA, Kucaba TA, Griffith TS, Hamilton SE, Schuldt NJ. Natural Microbial Exposure from the Earliest Natural Time Point Enhances Immune Development by Expanding Immune Cell Progenitors and Mature Immune Cells. J Immunol. 2023 Jun 1;210(11):1740-1751. doi: 10.4049/jimmunol.2300061. PubMed PMID: 37074206; PubMed Central PMCID: PMC10192123.

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Zachs DP, Offutt SJ, Graham RS, Kim Y, Mueller J, Auger JL, Schuldt NJ, Kaiser CRW, Heiller AP, Dutta R, Guo H, Alford JK, Binstadt BA, Lim HH. Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis. Nat Commun. 2019 Mar 12;10(1):951. doi: 10.1038/s41467-019-08721-0. PubMed PMID: 30862842; PubMed Central PMCID: PMC6414603.

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Schuldt NJ, Binstadt BA. Dual TCR T Cells: Identity Crisis or Multitaskers?. J Immunol. 2019 Feb 1;202(3):637-644. doi: 10.4049/jimmunol.1800904. Review. PubMed PMID: 30670579; PubMed Central PMCID: PMC11112972.

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Schuldt NJ, Auger JL, Spanier JA, Martinov T, Breed ER, Fife BT, Hogquist KA, Binstadt BA. Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation. J Immunol. 2017 Jul 1;199(1):33-38. doi: 10.4049/jimmunol.1700406. Epub 2017 May 24. PubMed PMID: 28539428; PubMed Central PMCID: PMC5501482.

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Schuldt NJ, Auger JL, Hogquist KA, Binstadt BA. Bi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis. PLoS One. 2015;10(12):e0145762. doi: 10.1371/journal.pone.0145762. eCollection 2015. PubMed PMID: 26693713; PubMed Central PMCID: PMC4687847.

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Aldhamen YA, Seregin SS, Schuldt NJ, Rastall DP, Liu CJ, Godbehere S, Amalfitano A. Vaccines expressing the innate immune modulator EAT-2 elicit potent effector memory T lymphocyte responses despite pre-existing vaccine immunity. J Immunol. 2012 Aug 1;189(3):1349-59. doi: 10.4049/jimmunol.1200736. Epub 2012 Jun 27. PubMed PMID: 22745373; PubMed Central PMCID: PMC11119577.

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Schuldt NJ, Amalfitano A. Malaria vaccines: focus on adenovirus based vectors. Vaccine. 2012 Jul 27;30(35):5191-8. doi: 10.1016/j.vaccine.2012.05.048. Epub 2012 Jun 7. Review. PubMed PMID: 22683663.

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Schuldt NJ, Aldhamen YA, Godbehere-Roosa S, Seregin SS, Kousa YA, Amalfitano A. Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and adenovirus (Ad5) immune mice. Malar J. 2012 Jun 21;11:209. doi: 10.1186/1475-2875-11-209. PubMed PMID: 22720732; PubMed Central PMCID: PMC3472263.

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Schuldt NJ, Aldhamen YA, Appledorn DM, Seregin SS, Kousa Y, Godbehere S, Amalfitano A. Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses. PLoS One. 2011;6(8):e24147. doi: 10.1371/journal.pone.0024147. Epub 2011 Aug 30. PubMed PMID: 21912619; PubMed Central PMCID: PMC3166157.

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Aldhamen YA, Appledorn DM, Seregin SS, Liu CJ, Schuldt NJ, Godbehere S, Amalfitano A. Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. J Immunol. 2011 Jan 15;186(2):722-32. doi: 10.4049/jimmunol.1002105. Epub 2010 Dec 13. PubMed PMID: 21149608; PubMed Central PMCID: PMC11119279.

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Seregin SS, Aldhamen YA, Appledorn DM, Hartman ZC, Schuldt NJ, Scott J, Godbehere S, Jiang H, Frank MM, Amalfitano A. Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo. Blood. 2010 Sep 9;116(10):1669-77. doi: 10.1182/blood-2010-03-276949. Epub 2010 May 28. PubMed PMID: 20511542; PubMed Central PMCID: PMC2947391.

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Appledorn DM, Aldhamen YA, Depas W, Seregin SS, Liu CJ, Schuldt N, Quach D, Quiroga D, Godbehere S, Zlatkin I, Kim S, McCormick JJ, Amalfitano A. A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target. PLoS One. 2010 Mar 8;5(3):e9579. doi: 10.1371/journal.pone.0009579. PubMed PMID: 20221448; PubMed Central PMCID: PMC2833191.

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Seregin SS, Aldhamen YA, Appledorn DM, Schuldt NJ, McBride AJ, Bujold M, Godbehere SS, Amalfitano A. CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies. Gene Ther. 2009 Oct;16(10):1245-59. doi: 10.1038/gt.2009.77. Epub 2009 Jun 25. PubMed PMID: 19554032; PubMed Central PMCID: PMC4039027.

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Seregin SS, Appledorn DM, McBride AJ, Schuldt NJ, Aldhamen YA, Voss T, Wei J, Bujold M, Nance W, Godbehere S, Amalfitano A. Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy. Mol Ther. 2009 Apr;17(4):685-96. doi: 10.1038/mt.2008.297. Epub 2009 Jan 27. PubMed PMID: 19174760; PubMed Central PMCID: PMC2835110.

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Appledorn DM, McBride A, Seregin S, Scott JM, Schuldt N, Kiang A, Godbehere S, Amalfitano A. Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors. Gene Ther. 2008 Dec;15(24):1606-17. doi: 10.1038/gt.2008.114. Epub 2008 Jul 10. PubMed PMID: 18615115; PubMed Central PMCID: PMC11112971.