My Bibliography

select

Brady A, Mora-Martinez LC, Hammond B, Haribabu B, Uriarte SM, Lawrenz MB. Distinct Mechanisms of Type 3 Secretion System Recognition Control LTB(4) Synthesis in Neutrophils versus Macrophages. bioRxiv. 2024 Jul 2;. doi: 10.1101/2024.07.01.601466. PubMed PMID: 39005373; PubMed Central PMCID: PMC11244889.

select

Brady A, Sheneman KR, Pulsifer AR, Price SL, Garrison TM, Maddipati KR, Bodduluri SR, Pan J, Boyd NL, Zheng JJ, Rai SN, Hellmann J, Haribabu B, Uriarte SM, Lawrenz MB. Type 3 secretion system induced leukotriene B4 synthesis by leukocytes is actively inhibited by Yersinia pestis to evade early immune recognition. PLoS Pathog. 2024 Jan;20(1):e1011280. doi: 10.1371/journal.ppat.1011280. eCollection 2024 Jan. PubMed PMID: 38271464; PubMed Central PMCID: PMC10846697.

select

Price SL, Oakes RS, Gonzalez RJ, Edwards C, Brady A, DeMarco JK, von Andrian UH, Jewell CM, Lawrenz MB. Microneedle array delivery of Yersinia pestis recapitulates bubonic plague. iScience. 2024 Jan 19;27(1):108600. doi: 10.1016/j.isci.2023.108600. eCollection 2024 Jan 19. PubMed PMID: 38179062; PubMed Central PMCID: PMC10765063.

select

Price SL, Thibault D, Garrison TM, Brady A, Guo H, Kehl-Fie TE, Garneau-Tsodikova S, Perry RD, van Opijnen T, Lawrenz MB. Droplet Tn-Seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis. EMBO Rep. 2023 Oct 9;24(10):e57369. doi: 10.15252/embr.202357369. Epub 2023 Jul 28. PubMed PMID: 37501563; PubMed Central PMCID: PMC10561177.

select

Warawa JM, Duan X, Anderson CD, Sotsky JB, Cramer DE, Pfeffer TL, Guo H, Adcock S, Lepak AJ, Andes DR, Slone SA, Stromberg AJ, Gabbard JD, Severson WE, Lawrenz MB. Validated Preclinical Mouse Model for Therapeutic Testing against Multidrug-Resistant Pseudomonas aeruginosa Strains. Microbiol Spectr. 2022 Oct 26;10(5):e0269322. doi: 10.1128/spectrum.02693-22. Epub 2022 Sep 12. PubMed PMID: 36094219; PubMed Central PMCID: PMC9603883.

select

Kumar A, Yang T, Chakravorty S, Majumdar A, Nairn BL, Six DA, Marcondes Dos Santos N, Price SL, Lawrenz MB, Actis LA, Marques M, Russo TA, Newton SM, Klebba PE. Fluorescent sensors of siderophores produced by bacterial pathogens. J Biol Chem. 2022 Mar;298(3):101651. doi: 10.1016/j.jbc.2022.101651. Epub 2022 Jan 29. PubMed PMID: 35101443; PubMed Central PMCID: PMC8921320.

select

Behnsen J, Zhi H, Aron AT, Subramanian V, Santus W, Lee MH, Gerner RR, Petras D, Liu JZ, Green KD, Price SL, Camacho J, Hillman H, Tjokrosurjo J, Montaldo NP, Hoover EM, Treacy-Abarca S, Gilston BA, Skaar EP, Chazin WJ, Garneau-Tsodikova S, Lawrenz MB, Perry RD, Nuccio SP, Dorrestein PC, Raffatellu M. Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut. Nat Commun. 2021 Dec 1;12(1):7016. doi: 10.1038/s41467-021-27297-2. PubMed PMID: 34853318; PubMed Central PMCID: PMC8636617.

select

Price SL, Vadyvaloo V, DeMarco JK, Brady A, Gray PA, Kehl-Fie TE, Garneau-Tsodikova S, Perry RD, Lawrenz MB. Yersiniabactin contributes to overcoming zinc restriction during Yersinia pestis infection of mammalian and insect hosts. Proc Natl Acad Sci U S A. 2021 Nov 2;118(44). doi: 10.1073/pnas.2104073118. PubMed PMID: 34716262; PubMed Central PMCID: PMC8612365.

select

Duplessis C, Warawa JM, Lawrenz MB, Henry M, Biswas B. Successful Intratracheal Treatment of Phage and Antibiotic Combination Therapy of a Multi-Drug Resistant Pseudomonas aeruginosa Murine Model. Antibiotics (Basel). 2021 Aug 5;10(8). doi: 10.3390/antibiotics10080946. PubMed PMID: 34438996; PubMed Central PMCID: PMC8388862.

select

Byrne JM, Waack U, Weinstein EA, Joshi A, Shurland SM, Iarikov D, Bulitta JB, Diep BA, Guina T, Hope WW, Lawrenz MB, Lepak AJ, Luna BM, Miesel L, Phipps AJ, Walsh TJ, Weiss W, Amini T, Farley JJ. FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development. Antimicrob Agents Chemother. 2020 Dec 16;65(1). doi: 10.1128/AAC.01983-20. Print 2020 Dec 16. Review. PubMed PMID: 33106262; PubMed Central PMCID: PMC7927847.

select

Lei C, Mu J, Teng Y, He L, Xu F, Zhang X, Sundaram K, Kumar A, Sriwastva MK, Lawrenz MB, Zhang L, Yan J, Feng W, McClain CJ, Zhang X, Zhang HG. Lemon Exosome-like Nanoparticles-Manipulated Probiotics Protect Mice from C. d iff Infection. iScience. 2020 Oct 23;23(10):101571. doi: 10.1016/j.isci.2020.101571. eCollection 2020 Oct 23. PubMed PMID: 33083738; PubMed Central PMCID: PMC7530291.

select

DiNubile MJ, Levinson SL, Stossel TP, Lawrenz MB, Warawa JM. Recombinant Human Plasma Gelsolin Improves Survival and Attenuates Lung Injury in a Murine Model of Multidrug-Resistant Pseudomonas aeruginosa Pneumonia. Open Forum Infect Dis. 2020 Aug;7(8):ofaa236. doi: 10.1093/ofid/ofaa236. eCollection 2020 Aug. PubMed PMID: 32766380; PubMed Central PMCID: PMC7397834.

select

Pulsifer AR, Vashishta A, Reeves SA, Wolfe JK, Palace SG, Proulx MK, Goguen J, Bodduluri SR, Haribabu B, Uriarte SM, Lawrenz MB. Redundant and Cooperative Roles for Yersinia pestis Yop Effectors in the Inhibition of Human Neutrophil Exocytic Responses Revealed by Gain-of-Function Approach. Infect Immun. 2020 Feb 20;88(3). doi: 10.1128/IAI.00909-19. Print 2020 Feb 20. PubMed PMID: 31871100; PubMed Central PMCID: PMC7035916.

select

Bowen W, Batra L, Pulsifer AR, Yolcu ES, Lawrenz MB, Shirwan H. Robust Th1 cellular and humoral responses generated by the Yersinia pestis rF1-V subunit vaccine formulated to contain an agonist of the CD137 pathway do not translate into increased protection against pneumonic plague. Vaccine. 2019 Sep 10;37(38):5708-5716. doi: 10.1016/j.vaccine.2019.07.103. Epub 2019 Aug 12. PubMed PMID: 31416643; PubMed Central PMCID: PMC6773249.

select

Will WR, Brzovic P, Le Trong I, Stenkamp RE, Lawrenz MB, Karlinsey JE, Navarre WW, Main-Hester K, Miller VL, Libby SJ, Fang FC. The Evolution of SlyA/RovA Transcription Factors from Repressors to Countersilencers in Enterobacteriaceae. mBio. 2019 Mar 5;10(2). doi: 10.1128/mBio.00009-19. PubMed PMID: 30837332; PubMed Central PMCID: PMC6401476.

select

Pulsifer AR, VanCleave TT, Lawrenz MB. Intracellular Assays to Monitor Survival and Growth of Yersinia pestis Within Macrophages. Methods Mol Biol. 2019;2010:181-196. doi: 10.1007/978-1-4939-9541-7_13. PubMed PMID: 31177439.

select

Hegde B, Bodduluri SR, Satpathy SR, Alghsham RS, Jala VR, Uriarte SM, Chung DH, Lawrenz MB, Haribabu B. Inflammasome-Independent Leukotriene B(4) Production Drives Crystalline Silica-Induced Sterile Inflammation. J Immunol. 2018 May 15;200(10):3556-3567. doi: 10.4049/jimmunol.1701504. Epub 2018 Apr 2. PubMed PMID: 29610142; PubMed Central PMCID: PMC5940517.

select

Connor MG, Pulsifer AR, Chung D, Rouchka EC, Ceresa BK, Lawrenz MB. Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia-Containing Vacuole To Avoid Killing by Macrophages. mBio. 2018 Feb 20;9(1). doi: 10.1128/mBio.01800-17. PubMed PMID: 29463656; PubMed Central PMCID: PMC5821078.

select

VanCleave TT, Pulsifer AR, Connor MG, Warawa JM, Lawrenz MB. Impact of Gentamicin Concentration and Exposure Time on Intracellular Yersinia pestis. Front Cell Infect Microbiol. 2017;7:505. doi: 10.3389/fcimb.2017.00505. eCollection 2017. PubMed PMID: 29312891; PubMed Central PMCID: PMC5732358.

select

Radka CD, DeLucas LJ, Wilson LS, Lawrenz MB, Perry RD, Aller SG. Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites. Acta Crystallogr D Struct Biol. 2017 Jul 1;73(Pt 7):557-572. doi: 10.1107/S2059798317006349. Epub 2017 Jun 30. PubMed PMID: 28695856; PubMed Central PMCID: PMC5505154.

select

Bobrov AG, Kirillina O, Fosso MY, Fetherston JD, Miller MC, VanCleave TT, Burlison JA, Arnold WK, Lawrenz MB, Garneau-Tsodikova S, Perry RD. Zinc transporters YbtX and ZnuABC are required for the virulence of Yersinia pestis in bubonic and pneumonic plague in mice. Metallomics. 2017 Jun 21;9(6):757-772. doi: 10.1039/c7mt00126f. PubMed PMID: 28540946; PubMed Central PMCID: PMC5532734.

select

Price C, Merchant M, Jones S, Best A, Von Dwingelo J, Lawrenz MB, Alam N, Schueler-Furman O, Kwaik YA. Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors. Front Cell Infect Microbiol. 2017;7:54. doi: 10.3389/fcimb.2017.00054. eCollection 2017. PubMed PMID: 28321389; PubMed Central PMCID: PMC5337513.

select

Payne JN, Waghwani HK, Connor MG, Hamilton W, Tockstein S, Moolani H, Chavda F, Badwaik V, Lawrenz MB, Dakshinamurthy R. Novel Synthesis of Kanamycin Conjugated Gold Nanoparticles with Potent Antibacterial Activity. Front Microbiol. 2016;7:607. doi: 10.3389/fmicb.2016.00607. eCollection 2016. PubMed PMID: 27330535; PubMed Central PMCID: PMC4908860.

select

Connor MG, Pulsifer AR, Price CT, Abu Kwaik Y, Lawrenz MB. Yersinia pestis Requires Host Rab1b for Survival in Macrophages. PLoS Pathog. 2015 Oct;11(10):e1005241. doi: 10.1371/journal.ppat.1005241. eCollection 2015 Oct. PubMed PMID: 26495854; PubMed Central PMCID: PMC4619670.

select

Lawrenz MB, Biller AE, Cramer DE, Kraenzle JL, Sotsky JB, Vanover CD, Yoder-Himes DR, Pollard A, Warawa JM. Development and evaluation of murine lung-specific disease models for Pseudomonas aeruginosa applicable to therapeutic testing. Pathog Dis. 2015 Jul;73(5). doi: 10.1093/femspd/ftv025. Epub 2015 Apr 9. PubMed PMID: 25857733; PubMed Central PMCID: PMC4849349.

select

Hamilton W, Modi T, Waghwani HK, Tockstein S, Payne J, Filani O, Badwaik V, Shah M, Webb C, Lawrenz MB, Dakshinamurthy R. Nanotechnology's Impact on Medicinal Chemistry. Mini Rev Med Chem. 2015 May 11;. [Epub ahead of print] PubMed PMID: 25963566.

select

Lawrenz MB, Fodah RA, Gutierrez MG, Warawa J. Intubation-mediated intratracheal (IMIT) instillation: a noninvasive, lung-specific delivery system. J Vis Exp. 2014 Nov 17;(93):e52261. doi: 10.3791/52261. PubMed PMID: 25490457; PubMed Central PMCID: PMC4354010.

select

Dinc G, Pennington JM, Yolcu ES, Lawrenz MB, Shirwan H. Improving the Th1 cellular efficacy of the lead Yersinia pestis rF1-V subunit vaccine using SA-4-1BBL as a novel adjuvant. Vaccine. 2014 Sep 3;32(39):5035-40. doi: 10.1016/j.vaccine.2014.07.015. Epub 2014 Jul 18. PubMed PMID: 25045812.

select

Shah M, Badwaik V, Kherde Y, Waghwani HK, Modi T, Aguilar ZP, Rodgers H, Hamilton W, Marutharaj T, Webb C, Lawrenz MB, Dakshinamurthy R. Gold nanoparticles: various methods of synthesis and antibacterial applications. Front Biosci (Landmark Ed). 2014 Jun 1;19(8):1320-44. doi: 10.2741/4284. Review. PubMed PMID: 24896353.

select

Warawa JM, Lawrenz MB. Bioluminescent imaging of bacteria during mouse infection. Methods Mol Biol. 2014;1098:169-81. doi: 10.1007/978-1-62703-718-1_14. PubMed PMID: 24166377.

select

Crespo F, Lawrenz MB. Heterogeneous Immunological Landscapes and Medieval Plague: An invitation to a New Dialogue between Historians and Immunologists. In: Green MH, editor. Pandemic Disease in the Medieval World: Rethinking the Black Death Kalamazoo, MI: Arc Medieval Press; 2014. p.229-258. 339p.

select

Lawrenz MB, Pennington J, Miller VL. Acquisition of omptin reveals cryptic virulence function of autotransporter YapE in Yersinia pestis. Mol Microbiol. 2013 Jul;89(2):276-87. doi: 10.1111/mmi.12273. Epub 2013 Jun 10. PubMed PMID: 23701256; PubMed Central PMCID: PMC3708302.

select

Sun Y, Connor MG, Pennington JM, Lawrenz MB. Development of bioluminescent bioreporters for in vitro and in vivo tracking of Yersinia pestis. PLoS One. 2012;7(10):e47123. doi: 10.1371/journal.pone.0047123. Epub 2012 Oct 11. PubMed PMID: 23071730; PubMed Central PMCID: PMC3469486.

select

Lenz JD, Lawrenz MB, Cotter DG, Lane MC, Gonzalez RJ, Palacios M, Miller VL. Expression during host infection and localization of Yersinia pestis autotransporter proteins. J Bacteriol. 2011 Nov;193(21):5936-49. doi: 10.1128/JB.05877-11. Epub 2011 Aug 26. PubMed PMID: 21873491; PubMed Central PMCID: PMC3194903.

select

Weening EH, Cathelyn JS, Kaufman G, Lawrenz MB, Price P, Goldman WE, Miller VL. The dependence of the Yersinia pestis capsule on pathogenesis is influenced by the mouse background. Infect Immun. 2011 Feb;79(2):644-52. doi: 10.1128/IAI.00981-10. Epub 2010 Nov 29. PubMed PMID: 21115720; PubMed Central PMCID: PMC3028848.

select

Lawrenz MB. Model systems to study plague pathogenesis and develop new therapeutics. Front Microbiol. 2010;1:119. doi: 10.3389/fmicb.2010.00119. eCollection 2010. PubMed PMID: 21687720; PubMed Central PMCID: PMC3109633.

select

Lawrenz MB, Lenz JD, Miller VL. A novel autotransporter adhesin is required for efficient colonization during bubonic plague. Infect Immun. 2009 Jan;77(1):317-26. doi: 10.1128/IAI.01206-08. Epub 2008 Oct 20. PubMed PMID: 18936182; PubMed Central PMCID: PMC2612260.

select

Felek S, Lawrenz MB, Krukonis ES. The Yersinia pestis autotransporter YapC mediates host cell binding, autoaggregation and biofilm formation. Microbiology (Reading). 2008 Jun;154(Pt 6):1802-1812. doi: 10.1099/mic.0.2007/010918-0. PubMed PMID: 18524935.

select

Lawrenz MB, Miller VL. Comparative analysis of the regulation of rovA from the pathogenic yersiniae. J Bacteriol. 2007 Aug;189(16):5963-75. doi: 10.1128/JB.00528-07. Epub 2007 Jun 15. PubMed PMID: 17573476; PubMed Central PMCID: PMC1952055.

select

Lawrenz MB, Wooten RM, Norris SJ. Effects of vlsE complementation on the infectivity of Borrelia burgdorferi lacking the linear plasmid lp28-1. Infect Immun. 2004 Nov;72(11):6577-85. doi: 10.1128/IAI.72.11.6577-6585.2004. PubMed PMID: 15501789; PubMed Central PMCID: PMC523020.

select

Ellison DW, Lawrenz MB, Miller VL. Invasin and beyond: regulation of Yersinia virulence by RovA. Trends Microbiol. 2004 Jun;12(6):296-300. doi: 10.1016/j.tim.2004.04.006. Review. PubMed PMID: 15165608.

select

Lawrenz MB, Wooten RM, Zachary JF, Drouin SM, Weis JJ, Wetsel RA, Norris SJ. Effect of complement component C3 deficiency on experimental Lyme borreliosis in mice. Infect Immun. 2003 Aug;71(8):4432-40. doi: 10.1128/IAI.71.8.4432-4440.2003. PubMed PMID: 12874322; PubMed Central PMCID: PMC165993.

select

Purser JE, Lawrenz MB, Caimano MJ, Howell JK, Radolf JD, Norris SJ. A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host. Mol Microbiol. 2003 May;48(3):753-64. doi: 10.1046/j.1365-2958.2003.03452.x. PubMed PMID: 12694619.

select

Lawrenz MB, Kawabata H, Purser JE, Norris SJ. Decreased electroporation efficiency in Borrelia burgdorferi containing linear plasmids lp25 and lp56: impact on transformation of infectious B. burgdorferi. Infect Immun. 2002 Sep;70(9):4798-804. doi: 10.1128/IAI.70.9.4798-4804.2002. PubMed PMID: 12183522; PubMed Central PMCID: PMC128261.

select

Magnarelli LA, Lawrenz M, Norris SJ, Fikrig E. Comparative reactivity of human sera to recombinant VlsE and other Borrelia burgdorferi antigens in class-specific enzyme-linked immunosorbent assays for Lyme borreliosis. J Med Microbiol. 2002 Aug;51(8):649-655. doi: 10.1099/0022-1317-51-8-649. PubMed PMID: 12171295.

select

Eicken C, Sharma V, Klabunde T, Lawrenz MB, Hardham JM, Norris SJ, Sacchettini JC. Crystal structure of Lyme disease variable surface antigen VlsE of Borrelia burgdorferi. J Biol Chem. 2002 Jun 14;277(24):21691-6. doi: 10.1074/jbc.M201547200. Epub 2002 Mar 28. PubMed PMID: 11923306.

select

Lawrenz MB, Hardham JM, Owens RT, Nowakowski J, Steere AC, Wormser GP, Norris SJ. Human antibody responses to VlsE antigenic variation protein of Borrelia burgdorferi. J Clin Microbiol. 1999 Dec;37(12):3997-4004. doi: 10.1128/JCM.37.12.3997-4004.1999. PubMed PMID: 10565921; PubMed Central PMCID: PMC85865.