My Bibliography

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Phénix J, Côté J, Dieme D, Recinto SJ, Oestereich F, Efrem S, Haddad S, Bouchard M, Munter LM. CETP inhibitor evacetrapib enters mouse brain tissue. Front Pharmacol. 2023;14:1171937. doi: 10.3389/fphar.2023.1171937. eCollection 2023. PubMed PMID: 37533630; PubMed Central PMCID: PMC10390775.

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Hsiao JM, Penalva YCM, Wu HY, Xiao B, Jansen G, Dejgaard K, Young JC, Munter LM. Putative Protein Interactome of the Rhomboid Protease RHBDL4. Biochemistry. 2023 Mar 21;62(6):1209-1218. doi: 10.1021/acs.biochem.2c00680. Epub 2023 Mar 1. PubMed PMID: 36857408.

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Oestereich F, Yousefpour N, Yang E, Phénix J, Nezhad ZS, Nitu A, Vázquez Cobá A, Ribeiro-da-Silva A, Chaurand P, Munter LM. The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain. J Lipid Res. 2022 Sep;63(9):100260. doi: 10.1016/j.jlr.2022.100260. Epub 2022 Jul 31. PubMed PMID: 35921880; PubMed Central PMCID: PMC9464954.

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Nezhad ZS, Salazar JP, Pryce RS, Munter LM, Chaurand P. Absolute quantification of cholesterol from thin tissue sections by silver-assisted laser desorption ionization mass spectrometry imaging. Anal Bioanal Chem. 2022 Sep;414(23):6947-6954. doi: 10.1007/s00216-022-04262-6. Epub 2022 Aug 11. PubMed PMID: 35953724.

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Munter LM. The lipid component of Alzheimer's disease research: An Editorial Highlight for "Brain region-specific amyloid plaque-associated myelin lipid loss, APOE deposition and disruption of the myelin sheath in familial Alzheimer's disease mice" on page 84. J Neurochem. 2020 Jul;154(1):7-10. doi: 10.1111/jnc.15025. Epub 2020 May 6. PubMed PMID: 32374412.

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Paschkowsky S, Hsiao JM, Young JC, Munter LM. The discovery of proteases and intramembrane proteolysis (1). Biochem Cell Biol. 2019 Jun;97(3):265-269. doi: 10.1139/bcb-2018-0186. Epub 2018 Aug 13. Review. PubMed PMID: 30102867.

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Luu L, Ciccotosto GD, Vella LJ, Cheng L, Roisman LC, Multhaup G, Hill AF, Munter LM, Cappai R. Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth. Mol Neurobiol. 2019 Jan;56(1):13-28. doi: 10.1007/s12035-018-1070-4. Epub 2018 Apr 19. PubMed PMID: 29675574.

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Recinto SJ, Paschkowsky S, Munter LM. An alternative processing pathway of APP reveals two distinct cleavage modes for rhomboid protease RHBDL4. Biol Chem. 2018 Nov 27;399(12):1399-1408. doi: 10.1515/hsz-2018-0259. PubMed PMID: 30171808.

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Paschkowsky S, Recinto SJ, Young JC, Bondar AN, Munter LM. Membrane cholesterol as regulator of human rhomboid protease RHBDL4. J Biol Chem. 2018 Oct 5;293(40):15556-15568. doi: 10.1074/jbc.RA118.002640. Epub 2018 Aug 24. PubMed PMID: 30143535; PubMed Central PMCID: PMC6177575.

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Paschkowsky S, Oestereich F, Munter LM. Embedded in the Membrane: How Lipids Confer Activity and Specificity to Intramembrane Proteases. J Membr Biol. 2018 Jun;251(3):369-378. doi: 10.1007/s00232-017-0008-5. Epub 2017 Dec 19. PubMed PMID: 29260282.

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Girouard H, Munter LM. The many faces of vascular cognitive impairment. J Neurochem. 2018 Mar;144(5):509-512. doi: 10.1111/jnc.14287. Epub 2018 Feb 11. PubMed PMID: 29430652.

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Leonhardt J, Villela DC, Teichmann A, Münter LM, Mayer MC, Mardahl M, Kirsch S, Namsolleck P, Lucht K, Benz V, Alenina N, Daniell N, Horiuchi M, Iwai M, Multhaup G, Schülein R, Bader M, Santos RA, Unger T, Steckelings UM. Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS. Hypertension. 2017 Jun;69(6):1128-1135. doi: 10.1161/HYPERTENSIONAHA.116.08814. Epub 2017 May 1. PubMed PMID: 28461604.

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Paschkowsky S, Hamzé M, Oestereich F, Munter LM. Alternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4. J Biol Chem. 2016 Oct 14;291(42):21903-21912. doi: 10.1074/jbc.M116.753582. Epub 2016 Aug 25. PubMed PMID: 27563067; PubMed Central PMCID: PMC5063975.

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Munter LM. How many amyloid-β peptides can a neuron bind before it dies?. J Neurochem. 2016 Feb;136(3):437-9. doi: 10.1111/jnc.13502. PubMed PMID: 26786571.

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Oestereich F, Bittner HJ, Weise C, Grohmann L, Janke LK, Hildebrand PW, Multhaup G, Munter LM. Impact of amyloid precursor protein hydrophilic transmembrane residues on amyloid-beta generation. Biochemistry. 2015 May 5;54(17):2777-84. doi: 10.1021/acs.biochem.5b00217. Epub 2015 Apr 23. PubMed PMID: 25875527.

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Iulita MF, Allard S, Richter L, Munter LM, Ducatenzeiler A, Weise C, Do Carmo S, Klein WL, Multhaup G, Cuello AC. Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study. Acta Neuropathol Commun. 2014 Jun 5;2:61. doi: 10.1186/2051-5960-2-61. PubMed PMID: 24903713; PubMed Central PMCID: PMC4229908.

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Olsson F, Schmidt S, Althoff V, Munter LM, Jin S, Rosqvist S, Lendahl U, Multhaup G, Lundkvist J. Characterization of intermediate steps in amyloid beta (Aβ) production under near-native conditions. J Biol Chem. 2014 Jan 17;289(3):1540-50. doi: 10.1074/jbc.M113.498246. Epub 2013 Nov 13. PubMed PMID: 24225948; PubMed Central PMCID: PMC3894335.

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Munter LM, Sieg H, Bethge T, Liebsch F, Bierkandt FS, Schleeger M, Bittner HJ, Heberle J, Jakubowski N, Hildebrand PW, Multhaup G. Model peptides uncover the role of the β-secretase transmembrane sequence in metal ion mediated oligomerization. J Am Chem Soc. 2013 Dec 26;135(51):19354-61. doi: 10.1021/ja410812r. Epub 2013 Dec 13. PubMed PMID: 24304299.

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Badiola N, Alcalde V, Pujol A, Münter LM, Multhaup G, Lleó A, Coma M, Soler-López M, Aloy P. The proton-pump inhibitor lansoprazole enhances amyloid beta production. PLoS One. 2013;8(3):e58837. doi: 10.1371/journal.pone.0058837. Epub 2013 Mar 8. PubMed PMID: 23520537; PubMed Central PMCID: PMC3592824.

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Resenberger UK, Müller V, Munter LM, Baier M, Multhaup G, Wilson MR, Winklhofer KF, Tatzelt J. The heat shock response is modulated by and interferes with toxic effects of scrapie prion protein and amyloid β. J Biol Chem. 2012 Dec 21;287(52):43765-76. doi: 10.1074/jbc.M112.389007. Epub 2012 Oct 31. PubMed PMID: 23115236; PubMed Central PMCID: PMC3527961.

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Bien J, Jefferson T, Causević M, Jumpertz T, Munter L, Multhaup G, Weggen S, Becker-Pauly C, Pietrzik CU. The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species. J Biol Chem. 2012 Sep 28;287(40):33304-13. doi: 10.1074/jbc.M112.395608. Epub 2012 Aug 9. PubMed PMID: 22879596; PubMed Central PMCID: PMC3460434.

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Kaden D, Harmeier A, Weise C, Munter LM, Althoff V, Rost BR, Hildebrand PW, Schmitz D, Schaefer M, Lurz R, Skodda S, Yamamoto R, Arlt S, Finckh U, Multhaup G. Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers. EMBO Mol Med. 2012 Jul;4(7):647-59. doi: 10.1002/emmm.201200239. Epub 2012 Apr 19. PubMed PMID: 22514144; PubMed Central PMCID: PMC3407951.

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Kaden D, Munter LM, Reif B, Multhaup G. The amyloid precursor protein and its homologues: structural and functional aspects of native and pathogenic oligomerization. Eur J Cell Biol. 2012 Apr;91(4):234-9. doi: 10.1016/j.ejcb.2011.01.017. Epub 2011 Apr 2. Review. PubMed PMID: 21459473.

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Hua H, Münter L, Harmeier A, Georgiev O, Multhaup G, Schaffner W. Toxicity of Alzheimer's disease-associated Aβ peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability. Biol Chem. 2011 Oct;392(10):919-26. doi: 10.1515/BC.2011.084. Epub 2011 Jul 30. PubMed PMID: 21801085.

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Heneka MT, Kummer MP, Weggen S, Bulic B, Multhaup G, Münter L, Hüll M, Pflanzner T, Pietrzik CU. Molecular mechanisms and therapeutic application of NSAIDs and derived compounds in Alzheimer's disease. Curr Alzheimer Res. 2011 Mar;8(2):115-31. doi: 10.2174/156720511795256099. Review. PubMed PMID: 21345168.

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Botev A, Munter LM, Wenzel R, Richter L, Althoff V, Ismer J, Gerling U, Weise C, Koksch B, Hildebrand PW, Bittl R, Multhaup G. The amyloid precursor protein C-terminal fragment C100 occurs in monomeric and dimeric stable conformations and binds γ-secretase modulators. Biochemistry. 2011 Feb 8;50(5):828-35. doi: 10.1021/bi1014002. Epub 2011 Jan 11. PubMed PMID: 21186781.

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Munter LM. 6th Fabisch symposium for cancer research and molecular cell biology--enzymes in physiology and pathogenesis: signaling by secretases. Neurodegener Dis. 2011;8(1-2):41-3. doi: 10.1159/000315402. Epub 2010 Aug 4. PubMed PMID: 20689251.

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Richter L, Munter LM, Ness J, Hildebrand PW, Dasari M, Unterreitmeier S, Bulic B, Beyermann M, Gust R, Reif B, Weggen S, Langosch D, Multhaup G. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602. doi: 10.1073/pnas.1003026107. Epub 2010 Aug 2. PubMed PMID: 20679249; PubMed Central PMCID: PMC2930477.

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Munter LM, Botev A, Richter L, Hildebrand PW, Althoff V, Weise C, Kaden D, Multhaup G. Aberrant amyloid precursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif. J Biol Chem. 2010 Jul 9;285(28):21636-43. doi: 10.1074/jbc.M109.088005. Epub 2010 May 7. PubMed PMID: 20452985; PubMed Central PMCID: PMC2898405.

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Harmeier A, Wozny C, Rost BR, Munter LM, Hua H, Georgiev O, Beyermann M, Hildebrand PW, Weise C, Schaffner W, Schmitz D, Multhaup G. Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity. J Neurosci. 2009 Jun 10;29(23):7582-90. doi: 10.1523/JNEUROSCI.1336-09.2009. PubMed PMID: 19515926; PubMed Central PMCID: PMC6665404.

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Treiber C, Quadir MA, Voigt P, Radowski M, Xu S, Munter LM, Bayer TA, Schaefer M, Haag R, Multhaup G. Cellular copper import by nanocarrier systems, intracellular availability, and effects on amyloid beta peptide secretion. Biochemistry. 2009 May 26;48(20):4273-84. doi: 10.1021/bi900290c. PubMed PMID: 19331399.

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Kaden D, Voigt P, Munter LM, Bobowski KD, Schaefer M, Multhaup G. Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2. J Cell Sci. 2009 Feb 1;122(Pt 3):368-77. doi: 10.1242/jcs.034058. Epub 2009 Jan 6. PubMed PMID: 19126676.

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Kaden D, Munter LM, Joshi M, Treiber C, Weise C, Bethge T, Voigt P, Schaefer M, Beyermann M, Reif B, Multhaup G. Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. J Biol Chem. 2008 Mar 14;283(11):7271-9. doi: 10.1074/jbc.M708046200. Epub 2008 Jan 8. PubMed PMID: 18182389.

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Munter LM, Voigt P, Harmeier A, Kaden D, Gottschalk KE, Weise C, Pipkorn R, Schaefer M, Langosch D, Multhaup G. GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. EMBO J. 2007 Mar 21;26(6):1702-12. doi: 10.1038/sj.emboj.7601616. Epub 2007 Mar 1. PubMed PMID: 17332749; PubMed Central PMCID: PMC1829382.

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Jahnel R, Bender O, Münter LM, Dreger M, Gillen C, Hucho F. Dual expression of mouse and rat VRL-1 in the dorsal root ganglion derived cell line F-11 and biochemical analysis of VRL-1 after heterologous expression. Eur J Biochem. 2003 Nov;270(21):4264-71. doi: 10.1046/j.1432-1033.2003.03811.x. PubMed PMID: 14622291.