My Bibliography

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Stewart New J, Glenn King R, Foote JB, Kearney JF. Microbiota and B-1 B cell repertoire development in mice. Curr Opin Immunol. 2024 Aug;89:102452. doi: 10.1016/j.coi.2024.102452. Epub 2024 Aug 23. Review. PubMed PMID: 39180941; PubMed Central PMCID: PMC11365744.

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New JS, Dizon BLP, Kearney JF, King RG. Glycan-Reactive Innate-like B Cells and Developmental Checkpoints. J Immunol. 2024 Jun 15;212(12):1913-1921. doi: 10.4049/jimmunol.2300587. PubMed PMID: 38647373; PubMed Central PMCID: PMC11147723.

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New JS, Dizon BLP, King RG, Greenspan NS, Kearney JF. B-1 B Cell-Derived Natural Antibodies against N-Acetyl-d-Glucosamine Suppress Autoimmune Diabetes Pathogenesis. J Immunol. 2023 Nov 1;211(9):1320-1331. doi: 10.4049/jimmunol.2300264. PubMed PMID: 37747293; PubMed Central PMCID: PMC10592000.

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Chattopadhyay D, Walker DR, Rich-New ST, Kearney JF, Turnbough CL Jr. Crystal structure and induced stability of trimeric BxpB: implications for the assembly of BxpB-BclA complexes in the exosporium of Bacillus anthracis. mBio. 2023 Aug 31;14(4):e0117223. doi: 10.1128/mbio.01172-23. Epub 2023 Jun 29. PubMed PMID: 37382447; PubMed Central PMCID: PMC10470788.

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Barington L, Christensen LVV, Pedersen KK, Niss Arfelt K, Roumain M, Jensen KHR, Kjær VMS, Daugvilaite V, Kearney JF, Christensen JP, Hjortø GM, Muccioli GG, Holst PJ, Rosenkilde MM. GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity. Cells. 2022 Jan 31;11(3). doi: 10.3390/cells11030494. PubMed PMID: 35159303; PubMed Central PMCID: PMC8834096.

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Cordero H, King RG, Dogra P, Dufeu C, See SB, Chong AM, Uhlemann AC, Ho SH, Kalfa DM, Bacha EA, Kearney JF, Zorn E. Intrathymic differentiation of natural antibody-producing plasma cells in human neonates. Nat Commun. 2021 Oct 1;12(1):5761. doi: 10.1038/s41467-021-26069-2. PubMed PMID: 34599177; PubMed Central PMCID: PMC8486820.

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New JS, Dizon BLP, Fucile CF, Rosenberg AF, Kearney JF, King RG. Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development. Immunity. 2020 Jul 14;53(1):172-186.e6. doi: 10.1016/j.immuni.2020.06.006. Epub 2020 Jun 30. PubMed PMID: 32610078; PubMed Central PMCID: PMC7971260.

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New JS, King RG, Kearney JF. Glycan Reactive Natural Antibodies and Viral Immunity. Viral Immunol. 2020 May;33(4):266-276. doi: 10.1089/vim.2019.0136. Epub 2019 Dec 17. Review. PubMed PMID: 31851873; PubMed Central PMCID: PMC7247037.

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Deng M, Guo H, Tam JW, Johnson BM, Brickey WJ, New JS, Lenox A, Shi H, Golenbock DT, Koller BH, McKinnon KP, Beutler B, Ting JP. Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR. J Exp Med. 2019 Dec 2;216(12):2838-2853. doi: 10.1084/jem.20190111. Epub 2019 Sep 26. PubMed PMID: 31558613; PubMed Central PMCID: PMC6888982.

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Komarova BS, Wong SSW, Orekhova MV, Tsvetkov YE, Krylov VB, Beauvais A, Bouchara JP, Kearney JF, Aimanianda V, Latgé JP, Nifantiev NE. Chemical Synthesis and Application of Biotinylated Oligo-α-(1 → 3)-d-Glucosides To Study the Antibody and Cytokine Response against the Cell Wall α-(1 → 3)-d-Glucan of Aspergillus fumigatus. J Org Chem. 2018 Nov 2;83(21):12965-12976. doi: 10.1021/acs.joc.8b01142. Epub 2018 Oct 16. PubMed PMID: 30277398; PubMed Central PMCID: PMC6461050.

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Belde V, Cravens MP, Gulandijany D, Walker JA, Palomo-Caturla I, Alugupalli AS, Sandilya VK, Mahmoud T, Bäumler AJ, Kearney JF, Alugupalli KR. Terminal Deoxynucleotidyl Transferase Is Not Required for Antibody Response to Polysaccharide Vaccines against Streptococcus pneumoniae and Salmonella enterica Serovar Typhi. Infect Immun. 2018 Sep;86(9). doi: 10.1128/IAI.00211-18. Print 2018 Sep. PubMed PMID: 29967094; PubMed Central PMCID: PMC6105908.

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Dickinson GS, Levenson EA, Walker JA, Kearney JF, Alugupalli KR. IL-7 Enables Antibody Responses to Bacterial Polysaccharides by Promoting B Cell Receptor Diversity. J Immunol. 2018 Aug 15;201(4):1229-1240. doi: 10.4049/jimmunol.1800162. Epub 2018 Jul 13. PubMed PMID: 30006375; PubMed Central PMCID: PMC6085875.

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Wang Y, Schafer CC, Hough KP, Tousif S, Duncan SR, Kearney JF, Ponnazhagan S, Hsu HC, Deshane JS. Myeloid-Derived Suppressor Cells Impair B Cell Responses in Lung Cancer through IL-7 and STAT5. J Immunol. 2018 Jul 1;201(1):278-295. doi: 10.4049/jimmunol.1701069. Epub 2018 May 11. PubMed PMID: 29752311; PubMed Central PMCID: PMC6008229.

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McDonald G, Medina CO, Pilichowska M, Kearney JF, Shinkura R, Selsing E, Wortis HH, Honjo T, Imanishi-Kari T. Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes. Front Immunol. 2017;8:1094. doi: 10.3389/fimmu.2017.01094. eCollection 2017. PubMed PMID: 28955333; PubMed Central PMCID: PMC5601273.

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Azzam KM, Madenspacher JH, Cain DW, Lai L, Gowdy KM, Rai P, Janardhan K, Clayton N, Cunningham W, Jensen H, Patel PS, Kearney JF, Taylor GA, Fessler MB. Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces. JCI Insight. 2017 Aug 17;2(16). doi: 10.1172/jci.insight.91914. eCollection 2017 Aug 17. PubMed PMID: 28814662; PubMed Central PMCID: PMC5621910.

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Patel PS, Kearney JF. CD36 and Platelet-Activating Factor Receptor Promote House Dust Mite Allergy Development. J Immunol. 2017 Aug 1;199(3):1184-1195. doi: 10.4049/jimmunol.1700034. Epub 2017 Jun 30. PubMed PMID: 28667161; PubMed Central PMCID: PMC5538133.

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Hammad H, Vanderkerken M, Pouliot P, Deswarte K, Toussaint W, Vergote K, Vandersarren L, Janssens S, Ramou I, Savvides SN, Haigh JJ, Hendriks R, Kopf M, Craessaerts K, de Strooper B, Kearney JF, Conrad DH, Lambrecht BN. Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10. Nat Immunol. 2017 Mar;18(3):313-320. doi: 10.1038/ni.3657. Epub 2017 Jan 9. PubMed PMID: 28068307.

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Patel P, Kearney JF. Immunological Outcomes of Antibody Binding to Glycans Shared between Microorganisms and Mammals. J Immunol. 2016 Dec 1;197(11):4201-4209. doi: 10.4049/jimmunol.1600872. Review. PubMed PMID: 27864551; PubMed Central PMCID: PMC5119654.

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Patel PS, King RG, Kearney JF. Pulmonary α-1,3-Glucan-Specific IgA-Secreting B Cells Suppress the Development of Cockroach Allergy. J Immunol. 2016 Oct 15;197(8):3175-3187. doi: 10.4049/jimmunol.1601039. Epub 2016 Aug 31. PubMed PMID: 27581173; PubMed Central PMCID: PMC5101147.

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New JS, King RG, Kearney JF. Manipulation of the glycan-specific natural antibody repertoire for immunotherapy. Immunol Rev. 2016 Mar;270(1):32-50. doi: 10.1111/imr.12397. Review. PubMed PMID: 26864103; PubMed Central PMCID: PMC4755354.

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Patel PS, Kearney JF. Neonatal exposure to pneumococcal phosphorylcholine modulates the development of house dust mite allergy during adult life. J Immunol. 2015 Jun 15;194(12):5838-50. doi: 10.4049/jimmunol.1500251. Epub 2015 May 8. PubMed PMID: 25957171; PubMed Central PMCID: PMC4456637.

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Wharton RE, Stefanov EK, King RG, Kearney JF. Antibodies generated against Streptococci protect in a mouse model of disseminated aspergillosis. J Immunol. 2015 May 1;194(9):4387-96. doi: 10.4049/jimmunol.1401940. Epub 2015 Mar 27. PubMed PMID: 25821219; PubMed Central PMCID: PMC4402265.

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Honjo K, Kubagawa Y, Kearney JF, Kubagawa H. Unique ligand-binding property of the human IgM Fc receptor. J Immunol. 2015 Feb 15;194(4):1975-82. doi: 10.4049/jimmunol.1401866. Epub 2015 Jan 19. PubMed PMID: 25601920; PubMed Central PMCID: PMC4711934.

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Kearney JF, Patel P, Stefanov EK, King RG. Natural antibody repertoires: development and functional role in inhibiting allergic airway disease. Annu Rev Immunol. 2015;33:475-504. doi: 10.1146/annurev-immunol-032713-120140. Epub 2015 Jan 22. Review. PubMed PMID: 25622195.

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Weindel CG, Richey LJ, Bolland S, Mehta AJ, Kearney JF, Huber BT. B cell autophagy mediates TLR7-dependent autoimmunity and inflammation. Autophagy. 2015;11(7):1010-24. doi: 10.1080/15548627.2015.1052206. PubMed PMID: 26120731; PubMed Central PMCID: PMC4590645.

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Vale AM, Kearney JF, Nobrega A, Schroeder HW. Development and Function of B Cell Subsets. In: Honjo T, Reth M, Radbruch A, Alt F, editors. Molecular Biology of B Cells Second Edition ed. New York: Elsevier; 2015. p.99-113.

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Umiker BR, Andersson S, Fernandez L, Korgaokar P, Larbi A, Pilichowska M, Weinkauf CC, Wortis HH, Kearney JF, Imanishi-Kari T. Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus. Eur J Immunol. 2014 May;44(5):1503-16. doi: 10.1002/eji.201344283. Epub 2014 Mar 20. PubMed PMID: 24500834; PubMed Central PMCID: PMC4028042.

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Rivera J, Morgenstern A, Bruchertseifer F, Kearney JF, Turnbough CL Jr, Dadachova E, Casadevall A. Microbicidal power of alpha radiation in sterilizing germinating Bacillus anthracis spores. Antimicrob Agents Chemother. 2014;58(3):1813-5. doi: 10.1128/AAC.01266-13. Epub 2013 Dec 30. PubMed PMID: 24379209; PubMed Central PMCID: PMC3957843.

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Yockey LJ, Demehri S, Turkoz M, Turkoz A, Ahern PP, Jassim O, Manivasagam S, Kearney JF, Gordon JI, Kopan R. The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation. J Invest Dermatol. 2013 Dec;133(12):2714-2721. doi: 10.1038/jid.2013.228. Epub 2013 May 22. PubMed PMID: 23698100; PubMed Central PMCID: PMC3796202.

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Song J, Lokmic Z, Lämmermann T, Rolf J, Wu C, Zhang X, Hallmann R, Hannocks MJ, Horn N, Ruegg MA, Sonnenberg A, Georges-Labouesse E, Winkler TH, Kearney JF, Cardell S, Sorokin L. Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2915-24. doi: 10.1073/pnas.1218131110. Epub 2013 Jul 11. PubMed PMID: 23847204; PubMed Central PMCID: PMC3732919.

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Vale AM, Kapoor P, Skibinski GA, Elgavish A, Mahmoud TI, Zemlin C, Zemlin M, Burrows PD, Nobrega A, Kearney JF, Briles DE, Schroeder HW Jr. The link between antibodies to OxLDL and natural protection against pneumococci depends on D(H) gene conservation. J Exp Med. 2013 May 6;210(5):875-90. doi: 10.1084/jem.20121861. PubMed PMID: 23589567; PubMed Central PMCID: PMC3646500.

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Honjo K, Kubagawa Y, Jones DM, Dizon B, Zhu Z, Ohno H, Izui S, Kearney JF, Kubagawa H. Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (FcμR). Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15882-7. doi: 10.1073/pnas.1206567109. Epub 2012 Sep 10. PubMed PMID: 22984178; PubMed Central PMCID: PMC3465379.

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Kin NW, Stefanov EK, Dizon BL, Kearney JF. Antibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway disease. J Immunol. 2012 Sep 1;189(5):2246-56. doi: 10.4049/jimmunol.1200702. Epub 2012 Jul 25. PubMed PMID: 22837487; PubMed Central PMCID: PMC3891668.

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Foote JB, Mahmoud TI, Vale AM, Kearney JF. Long-term maintenance of polysaccharide-specific antibodies by IgM-secreting cells. J Immunol. 2012 Jan 1;188(1):57-67. doi: 10.4049/jimmunol.1100783. Epub 2011 Nov 23. PubMed PMID: 22116821; PubMed Central PMCID: PMC3244511.

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Kin NW, Chen Y, Stefanov EK, Gallo RL, Kearney JF. Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function. Eur J Immunol. 2011 Oct;41(10):3006-16. doi: 10.1002/eji.201141606. Epub 2011 Aug 31. PubMed PMID: 21773974; PubMed Central PMCID: PMC3234162.

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Mahmoud TI, Schroeder HW Jr, Kearney JF. Limiting CDR-H3 diversity abrogates the antibody response to the bacterial polysaccharide α 1→3 dextran. J Immunol. 2011 Jul 15;187(2):879-86. doi: 10.4049/jimmunol.1100957. Epub 2011 Jun 15. PubMed PMID: 21677133; PubMed Central PMCID: PMC3210069.

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You Y, Myers RC, Freeberg L, Foote J, Kearney JF, Justement LB, Carter RH. Marginal zone B cells regulate antigen capture by marginal zone macrophages. J Immunol. 2011 Feb 15;186(4):2172-81. doi: 10.4049/jimmunol.1002106. Epub 2011 Jan 21. PubMed PMID: 21257969; PubMed Central PMCID: PMC3099422.

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McPherson SA, Li M, Kearney JF, Turnbough CL Jr. ExsB, an unusually highly phosphorylated protein required for the stable attachment of the exosporium of Bacillus anthracis. Mol Microbiol. 2010 Jun;76(6):1527-38. doi: 10.1111/j.1365-2958.2010.07182.x. Epub 2010 Apr 23. PubMed PMID: 20444088; PubMed Central PMCID: PMC4339267.

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Mahmoud TI, Kearney JF. Terminal deoxynucleotidyl transferase is required for an optimal response to the polysaccharide α-1,3 dextran. J Immunol. 2010 Jan 15;184(2):851-8. doi: 10.4049/jimmunol.0902791. Epub 2009 Dec 16. PubMed PMID: 20018621; PubMed Central PMCID: PMC4710363.

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Foote JB, Kearney JF. Generation of B cell memory to the bacterial polysaccharide alpha-1,3 dextran. J Immunol. 2009 Nov 15;183(10):6359-68. doi: 10.4049/jimmunol.0902473. Epub 2009 Oct 19. PubMed PMID: 19841173; PubMed Central PMCID: PMC3235742.

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Srinivasan L, Sasaki Y, Calado DP, Zhang B, Paik JH, DePinho RA, Kutok JL, Kearney JF, Otipoby KL, Rajewsky K. PI3 kinase signals BCR-dependent mature B cell survival. Cell. 2009 Oct 30;139(3):573-86. doi: 10.1016/j.cell.2009.08.041. PubMed PMID: 19879843; PubMed Central PMCID: PMC2787092.

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Oliva C, Turnbough CL Jr, Kearney JF. CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13957-62. doi: 10.1073/pnas.0902392106. Epub 2009 Jul 28. PubMed PMID: 19666536; PubMed Central PMCID: PMC2729002.

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Lisanby MW, Swiecki MK, Dizon BL, Pflughoeft KJ, Koehler TM, Kearney JF. Cathelicidin administration protects mice from Bacillus anthracis spore challenge. J Immunol. 2008 Oct 1;181(7):4989-5000. doi: 10.4049/jimmunol.181.7.4989. PubMed PMID: 18802102; PubMed Central PMCID: PMC4225133.

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Torii I, Oka S, Hotomi M, Benjamin WH Jr, Takai T, Kearney JF, Briles DE, Kubagawa H. PIR-B-deficient mice are susceptible to Salmonella infection. J Immunol. 2008 Sep 15;181(6):4229-39. doi: 10.4049/jimmunol.181.6.4229. PubMed PMID: 18768880; PubMed Central PMCID: PMC2613810.

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Kin NW, Crawford DM, Liu J, Behrens TW, Kearney JF. DNA microarray gene expression profile of marginal zone versus follicular B cells and idiotype positive marginal zone B cells before and after immunization with Streptococcus pneumoniae. J Immunol. 2008 May 15;180(10):6663-6674. doi: 10.4049/jimmunol.180.10.6663. PubMed PMID: 18453586; PubMed Central PMCID: PMC3966313.

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Kearney JF. B cell subpopulations and secondary lymphoid organ architecture. Semin Immunol. 2008 Feb;20(1):1-3. doi: 10.1016/j.smim.2007.10.014. Epub 2008 Feb 12. PubMed PMID: 18272389; PubMed Central PMCID: PMC2387049.

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Oliva CR, Swiecki MK, Griguer CE, Lisanby MW, Bullard DC, Turnbough CL Jr, Kearney JF. The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes. Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1261-6. doi: 10.1073/pnas.0709321105. Epub 2008 Jan 23. PubMed PMID: 18216258; PubMed Central PMCID: PMC2234126.

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Won WJ, Bachmann MF, Kearney JF. CD36 is differentially expressed on B cell subsets during development and in responses to antigen. J Immunol. 2008 Jan 1;180(1):230-7. doi: 10.4049/jimmunol.180.1.230. PubMed PMID: 18097024.

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Liu Y, Li L, Kumar KR, Xie C, Lightfoot S, Zhou XJ, Kearney JF, Weigert M, Mohan C. Lupus susceptibility genes may breach tolerance to DNA by impairing receptor editing of nuclear antigen-reactive B cells. J Immunol. 2007 Jul 15;179(2):1340-52. doi: 10.4049/jimmunol.179.2.1340. PubMed PMID: 17617627.

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Steichen CT, Kearney JF, Turnbough CL Jr. Non-uniform assembly of the Bacillus anthracis exosporium and a bottle cap model for spore germination and outgrowth. Mol Microbiol. 2007 Apr;64(2):359-67. doi: 10.1111/j.1365-2958.2007.05658.x. PubMed PMID: 17493122.