My Bibliography

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Verjans E, Kanzler S, Ohl K, Rieg AD, Ruske N, Schippers A, Wagner N, Tenbrock K, Uhlig S, Martin C. Initiation of LPS-induced pulmonary dysfunction and its recovery occur independent of T cells. BMC Pulm Med. 2018 Nov 22;18(1):174. doi: 10.1186/s12890-018-0741-2. PubMed PMID: 30466430; PubMed Central PMCID: PMC6251177.

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Krabbe J, Esser A, Kanzler S, Braunschweig T, Kintsler S, Spillner J, Schröder T, Kalverkamp S, Balakirski G, Gerhards B, Rieg AD, Kraus T, Brand P, Martin C. The effects of zinc- and copper-containing welding fumes on murine, rat and human precision-cut lung slices. J Trace Elem Med Biol. 2018 Sep;49:192-201. doi: 10.1016/j.jtemb.2018.03.008. Epub 2018 Mar 10. PubMed PMID: 29551464.

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Rieg AD, Suleiman S, Anker C, Verjans E, Rossaint R, Uhlig S, Martin C. PDGF-BB regulates the pulmonary vascular tone: impact of prostaglandins, calcium, MAPK- and PI3K/AKT/mTOR signalling and actin polymerisation in pulmonary veins of guinea pigs. Respir Res. 2018 Jun 19;19(1):120. doi: 10.1186/s12931-018-0829-5. PubMed PMID: 29921306; PubMed Central PMCID: PMC6009037.

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Neuhaus V, Danov O, Konzok S, Obernolte H, Dehmel S, Braubach P, Jonigk D, Fieguth HG, Zardo P, Warnecke G, Martin C, Braun A, Sewald K. Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices. J Vis Exp. 2018 May 9;(135). doi: 10.3791/57042. PubMed PMID: 29806827; PubMed Central PMCID: PMC6101160.

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Krabbe J, Ruske N, Braunschweig T, Kintsler S, Spillner JW, Schröder T, Kalverkamp S, Kanzler S, Rieg AD, Uhlig S, Martin C. The effects of hydroxyethyl starch and gelatine on pulmonary cytokine production and oedema formation. Sci Rep. 2018 Mar 23;8(1):5123. doi: 10.1038/s41598-018-23513-0. PubMed PMID: 29572534; PubMed Central PMCID: PMC5865122.

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Birzle AM, Martin C, Yoshihara L, Uhlig S, Wall WA. Experimental characterization and model identification of the nonlinear compressible material behavior of lung parenchyma. J Mech Behav Biomed Mater. 2018 Jan;77:754-763. doi: 10.1016/j.jmbbm.2017.08.001. Epub 2017 Aug 5. PubMed PMID: 28822739.

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Reiter J, Levina N, van der Linden M, Gruhlke M, Martin C, Slusarenko AJ. Diallylthiosulfinate (Allicin), a Volatile Antimicrobial from Garlic (Allium sativum), Kills Human Lung Pathogenic Bacteria, Including MDR Strains, as a Vapor. Molecules. 2017 Oct 12;22(10). doi: 10.3390/molecules22101711. PubMed PMID: 29023413; PubMed Central PMCID: PMC6151386.

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Maihöfer NA, Suleiman S, Dreymüller D, Manley PW, Rossaint R, Uhlig S, Martin C, Rieg AD. Imatinib relaxes the pulmonary venous bed of guinea pigs. Respir Res. 2017 Feb 8;18(1):32. doi: 10.1186/s12931-017-0514-0. PubMed PMID: 28178968; PubMed Central PMCID: PMC5299687.

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Männ L, Kochupurakkal N, Martin C, Verjans E, Klingberg A, Sody S, Kraus A, Dalimot J, Bergmüller E, Jung S, Voortman S, Winterhager E, Brandau S, Garbi N, Kurrer M, Eriksson U, Gunzer M, Hasenberg M. CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin. Eur J Immunol. 2016 Aug;46(8):2028-42. doi: 10.1002/eji.201546245. Epub 2016 Jun 8. PubMed PMID: 27184067.

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Hess A, Wang-Lauenstein L, Braun A, Kolle SN, Landsiedel R, Liebsch M, Ma-Hock L, Pirow R, Schneider X, Steinfath M, Vogel S, Martin C, Sewald K. Prevalidation of the ex-vivo model PCLS for prediction of respiratory toxicity. Toxicol In Vitro. 2016 Apr;32:347-61. doi: 10.1016/j.tiv.2016.01.006. Epub 2016 Jan 9. PubMed PMID: 26778741.

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Verjans E, Ohl K, Reiss LK, van Wijk F, Toncheva AA, Wiener A, Yu Y, Rieg AD, Gaertner VD, Roth J, Knol E, Kabesch M, Wagner N, Uhlig S, Martin C, Tenbrock K. The cAMP response element modulator (CREM) regulates TH2 mediated inflammation. Oncotarget. 2015 Nov 17;6(36):38538-51. doi: 10.18632/oncotarget.6041. PubMed PMID: 26459392; PubMed Central PMCID: PMC4770719.

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Reiss LK, Fragoulis A, Siegl S, Platen C, Kan YW, Nautiyal J, Parker M, Pufe T, Uhlig U, Martin C, Uhlig S, Wruck CJ. Interplay between nuclear factor erythroid 2-related factor 2 and amphiregulin during mechanical ventilation. Am J Respir Cell Mol Biol. 2014 Nov;51(5):668-77. doi: 10.1165/rcmb.2013-0279OC. PubMed PMID: 24921206.

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Lambermont VA, Schlepütz M, Dassow C, König P, Zimmermann LJ, Uhlig S, Kramer BW, Martin C. Comparison of airway responses in sheep of different age in precision-cut lung slices (PCLS). PLoS One. 2014;9(9):e97610. doi: 10.1371/journal.pone.0097610. eCollection 2014. PubMed PMID: 25229890; PubMed Central PMCID: PMC4167544.

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Pruessmeyer J, Hess FM, Alert H, Groth E, Pasqualon T, Schwarz N, Nyamoya S, Kollert J, van der Vorst E, Donners M, Martin C, Uhlig S, Saftig P, Dreymueller D, Ludwig A. Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space. Blood. 2014 Jun 26;123(26):4077-88. doi: 10.1182/blood-2013-09-511543. Epub 2014 May 15. PubMed PMID: 24833351.

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Rieg AD, Suleiman S, Perez-Bouza A, Braunschweig T, Spillner JW, Schröder T, Verjans E, Schälte G, Rossaint R, Uhlig S, Martin C. Milrinone relaxes pulmonary veins in guinea pigs and humans. PLoS One. 2014;9(1):e87685. doi: 10.1371/journal.pone.0087685. eCollection 2014. PubMed PMID: 24498166; PubMed Central PMCID: PMC3909212.

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Dreymueller D, Martin C, Schumacher J, Groth E, Boehm JK, Reiss LK, Uhlig S, Ludwig A. Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes. J Immunol. 2014 Jan 15;192(2):722-31. doi: 10.4049/jimmunol.1302496. Epub 2013 Dec 16. PubMed PMID: 24342803.

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Bel-Brunon A, Kehl S, Martin C, Uhlig S, Wall WA. Numerical identification method for the non-linear viscoelastic compressible behavior of soft tissue using uniaxial tensile tests and image registration - application to rat lung parenchyma. J Mech Behav Biomed Mater. 2014 Jan;29:360-74. doi: 10.1016/j.jmbbm.2013.09.018. Epub 2013 Oct 3. PubMed PMID: 24184860.

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Verjans E, Ohl K, Yu Y, Lippe R, Schippers A, Wiener A, Roth J, Wagner N, Uhlig S, Tenbrock K, Martin C. Overexpression of CREMα in T cells aggravates lipopolysaccharide-induced acute lung injury. J Immunol. 2013 Aug 1;191(3):1316-23. doi: 10.4049/jimmunol.1203147. Epub 2013 Jun 19. PubMed PMID: 23785120.

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Rieg AD, Rossaint R, Verjans E, Maihöfer NA, Uhlig S, Martin C. Levosimendan Relaxes Pulmonary Arteries and Veins in Precision-Cut Lung Slices - The Role of KATP-Channels, cAMP and cGMP. PLoS One. 2013;8(6):e66195. doi: 10.1371/journal.pone.0066195. Print 2013. PubMed PMID: 23824760; PubMed Central PMCID: PMC3688856.

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Wehr A, Baeck C, Heymann F, Niemietz PM, Hammerich L, Martin C, Zimmermann HW, Pack O, Gassler N, Hittatiya K, Ludwig A, Luedde T, Trautwein C, Tacke F. Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis. J Immunol. 2013 May 15;190(10):5226-36. doi: 10.4049/jimmunol.1202909. Epub 2013 Apr 17. PubMed PMID: 23596313.

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Yousefi OS, Wilhelm T, Maschke-Neuß K, Kuhny M, Martin C, Molderings GJ, Kratz F, Hildenbrand B, Huber M. The 1,4-benzodiazepine Ro5-4864 (4-chlorodiazepam) suppresses multiple pro-inflammatory mast cell effector functions. Cell Commun Signal. 2013 Feb 20;11(1):13. doi: 10.1186/1478-811X-11-13. PubMed PMID: 23425659; PubMed Central PMCID: PMC3598916.

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Larsson-Callerfelt AK, Dahlén SE, Kühl AR, Lex D, Uhlig S, Martin C. Modulation of antigen-induced responses by serotonin and prostaglandin E2 via EP1 and EP4 receptors in the peripheral rat lung. Eur J Pharmacol. 2013 Jan 15;699(1-3):141-9. doi: 10.1016/j.ejphar.2012.11.039. Epub 2012 Dec 3. PubMed PMID: 23220160.

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Schlepütz M, Rieg AD, Seehase S, Spillner J, Perez-Bouza A, Braunschweig T, Schroeder T, Bernau M, Lambermont V, Schlumbohm C, Sewald K, Autschbach R, Braun A, Kramer BW, Uhlig S, Martin C. Neurally mediated airway constriction in human and other species: a comparative study using precision-cut lung slices (PCLS). PLoS One. 2012;7(10):e47344. doi: 10.1371/journal.pone.0047344. Epub 2012 Oct 9. PubMed PMID: 23056631; PubMed Central PMCID: PMC3467211.

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Dreymueller D, Martin C, Kogel T, Pruessmeyer J, Hess FM, Horiuchi K, Uhlig S, Ludwig A. Lung endothelial ADAM17 regulates the acute inflammatory response to lipopolysaccharide. EMBO Mol Med. 2012 May;4(5):412-23. doi: 10.1002/emmm.201200217. Epub 2012 Feb 24. PubMed PMID: 22367719; PubMed Central PMCID: PMC3403298.

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Rieg AD, Rossaint R, Uhlig S, Martin C. Cardiovascular agents affect the tone of pulmonary arteries and veins in precision-cut lung slices. PLoS One. 2011;6(12):e29698. doi: 10.1371/journal.pone.0029698. Epub 2011 Dec 27. PubMed PMID: 22216346; PubMed Central PMCID: PMC3246495.

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Seehase S, Schlepütz M, Switalla S, Mätz-Rensing K, Kaup FJ, Zöller M, Schlumbohm C, Fuchs E, Lauenstein HD, Winkler C, Kuehl AR, Uhlig S, Braun A, Sewald K, Martin C. Bronchoconstriction in nonhuman primates: a species comparison. J Appl Physiol (1985). 2011 Sep;111(3):791-8. doi: 10.1152/japplphysiol.00162.2011. Epub 2011 Jun 23. PubMed PMID: 21700889.

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Rausch SM, Martin C, Bornemann PB, Uhlig S, Wall WA. Material model of lung parenchyma based on living precision-cut lung slice testing. J Mech Behav Biomed Mater. 2011 May;4(4):583-92. doi: 10.1016/j.jmbbm.2011.01.006. Epub 2011 Feb 3. PubMed PMID: 21396607.

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Schlepütz M, Uhlig S, Martin C. Electric field stimulation of precision-cut lung slices. J Appl Physiol (1985). 2011 Feb;110(2):545-54. doi: 10.1152/japplphysiol.00409.2010. Epub 2010 Nov 25. PubMed PMID: 21109600.

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Dassow C, Wiechert L, Martin C, Schumann S, Müller-Newen G, Pack O, Guttmann J, Wall WA, Uhlig S. Biaxial distension of precision-cut lung slices. J Appl Physiol (1985). 2010 Mar;108(3):713-21. doi: 10.1152/japplphysiol.00229.2009. Epub 2010 Jan 14. PubMed PMID: 20075265.

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Pruessmeyer J, Martin C, Hess FM, Schwarz N, Schmidt S, Kogel T, Hoettecke N, Schmidt B, Sechi A, Uhlig S, Ludwig A. A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cells. J Biol Chem. 2010 Jan 1;285(1):555-64. doi: 10.1074/jbc.M109.059394. Epub 2009 Oct 29. PubMed PMID: 19875451; PubMed Central PMCID: PMC2804204.

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Henjakovic M, Martin C, Hoymann HG, Sewald K, Ressmeyer AR, Dassow C, Pohlmann G, Krug N, Uhlig S, Braun A. Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies. Toxicol Sci. 2008 Dec;106(2):444-53. doi: 10.1093/toxsci/kfn178. Epub 2008 Sep 4. PubMed PMID: 18775882.

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Henjakovic M, Sewald K, Switalla S, Kaiser D, Müller M, Veres TZ, Martin C, Uhlig S, Krug N, Braun A. Ex vivo testing of immune responses in precision-cut lung slices. Toxicol Appl Pharmacol. 2008 Aug 15;231(1):68-76. doi: 10.1016/j.taap.2008.04.003. Epub 2008 Apr 11. PubMed PMID: 18504053.

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Lang DS, Droemann D, Schultz H, Branscheid D, Martin C, Ressmeyer AR, Zabel P, Vollmer E, Goldmann T. A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy. Respir Res. 2007 Jun 14;8(1):43. doi: 10.1186/1465-9921-8-43. PubMed PMID: 17567922; PubMed Central PMCID: PMC1913052.

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Sausbier M, Zhou XB, Beier C, Sausbier U, Wolpers D, Maget S, Martin C, Dietrich A, Ressmeyer AR, Renz H, Schlossmann J, Hofmann F, Neuhuber W, Gudermann T, Uhlig S, Korth M, Ruth P. Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel. FASEB J. 2007 Mar;21(3):812-22. doi: 10.1096/fj.06-7167com. Epub 2006 Dec 28. PubMed PMID: 17197382.

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Heinzelmann F, Jendrossek V, Lauber K, Nowak K, Eldh T, Boras R, Handrick R, Henkel M, Martin C, Uhlig S, Köhler D, Eltzschig HK, Wehrmann M, Budach W, Belka C. Irradiation-induced pneumonitis mediated by the CD95/CD95-ligand system. J Natl Cancer Inst. 2006 Sep 6;98(17):1248-51. doi: 10.1093/jnci/djj335. PubMed PMID: 16954477.

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Ressmeyer AR, Larsson AK, Vollmer E, Dahlèn SE, Uhlig S, Martin C. Characterisation of guinea pig precision-cut lung slices: comparison with human tissues. Eur Respir J. 2006 Sep;28(3):603-11. doi: 10.1183/09031936.06.00004206. Epub 2006 May 31. PubMed PMID: 16737991.

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Erpenbeck VJ, Ziegert M, Cavalet-Blanco D, Martin C, Baelder R, Glaab T, Braun A, Steinhilber W, Luettig B, Uhlig S, Hoymann HG, Krug N, Hohlfeld JM. Surfactant protein D inhibits early airway response in Aspergillus fumigatus-sensitized mice. Clin Exp Allergy. 2006 Jul;36(7):930-40. doi: 10.1111/j.1365-2222.2006.02524.x. PubMed PMID: 16839409.

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Karagiannidis C, Hense G, Martin C, Epstein M, Rückert B, Mantel PY, Menz G, Uhlig S, Blaser K, Schmidt-Weber CB. Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma. J Allergy Clin Immunol. 2006 Jan;117(1):111-8. doi: 10.1016/j.jaci.2005.09.017. Epub 2005 Nov 8. PubMed PMID: 16387593.

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Kuebler WM, Uhlig U, Goldmann T, Schael G, Kerem A, Exner K, Martin C, Vollmer E, Uhlig S. Stretch activates nitric oxide production in pulmonary vascular endothelial cells in situ. Am J Respir Crit Care Med. 2003 Dec 1;168(11):1391-8. doi: 10.1164/rccm.200304-562OC. Epub 2003 Aug 28. PubMed PMID: 12947026.

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Calandra T, Froidevaux C, Martin C, Roger T. Macrophage migration inhibitory factor and host innate immune defenses against bacterial sepsis. J Infect Dis. 2003 Jun 15;187 Suppl 2:S385-90. doi: 10.1086/374752. PubMed PMID: 12792855.

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Wohlsen A, Martin C, Vollmer E, Branscheid D, Magnussen H, Becker WM, Lepp U, Uhlig S. The early allergic response in small airways of human precision-cut lung slices. Eur Respir J. 2003 Jun;21(6):1024-32. doi: 10.1183/09031936.03.00027502. PubMed PMID: 12797499.

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Roger T, Froidevaux C, Martin C, Calandra T. Macrophage migration inhibitory factor (MIF) regulates host responses to endotoxin through modulation of Toll-like receptor 4 (TLR4). J Endotoxin Res. 2003;9(2):119-23. doi: 10.1179/096805103125001513. PubMed PMID: 12803886.

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Martin C, Göggel R, Dal Piaz V, Vergelli C, Giovannoni P, Ernst M, Uhlig S. Airway relaxant and anti-inflammatory properties of a PDE4 inhibitor with low affinity for the high-affinity rolipram binding site. Naunyn Schmiedebergs Arch Pharmacol. 2002 Apr;365(4):284-9. doi: 10.1007/s00210-001-0525-7. Epub 2002 Feb 27. PubMed PMID: 11919652.

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Froidevaux C, Roger T, Martin C, Glauser MP, Calandra T. Macrophage migration inhibitory factor and innate immune responses to bacterial infections. Crit Care Med. 2001 Jul;29(7 Suppl):S13-5. doi: 10.1097/00003246-200107001-00006. Review. PubMed PMID: 11445727.

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Wohlsen A, Uhlig S, Martin C. Immediate allergic response in small airways. Am J Respir Crit Care Med. 2001 May;163(6):1462-9. doi: 10.1164/ajrccm.163.6.2007138. PubMed PMID: 11371419.

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Martin C, Wohlsen A, Uhlig S. Changes in airway resistance by simultaneous exposure to TNF-alpha and IL-1beta in perfused rat lungs. Am J Physiol Lung Cell Mol Physiol. 2001 Apr;280(4):L595-601. doi: 10.1152/ajplung.2001.280.4.L595. PubMed PMID: 11237998.

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Martin C, Uhlig S, Ullrich V. Cytokine-induced bronchoconstriction in precision-cut lung slices is dependent upon cyclooxygenase-2 and thromboxane receptor activation. Am J Respir Cell Mol Biol. 2001 Feb;24(2):139-45. doi: 10.1165/ajrcmb.24.2.3545. PubMed PMID: 11159047.

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Martin C, Held HD, Uhlig S. Differential effects of the mixed ET(A)/ET(B)-receptor antagonist bosentan on endothelin-induced bronchoconstriction, vasoconstriction and prostacyclin release. Naunyn Schmiedebergs Arch Pharmacol. 2000 Aug;362(2):128-36. doi: 10.1007/s002100000264. PubMed PMID: 10961375.

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Martin C, Ullrich V, Uhlig S. Effects of the thromboxane receptor agonist U46619 and endothelin-1 on large and small airways. Eur Respir J. 2000 Aug;16(2):316-23. doi: 10.1034/j.1399-3003.2000.16b21.x. PubMed PMID: 10968509.

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Verbrugge SJ, Uhlig S, Neggers SJ, Martin C, Held HD, Haitsma JJ, Lachmann B. Different ventilation strategies affect lung function but do not increase tumor necrosis factor-alpha and prostacyclin production in lavaged rat lungs in vivo. Anesthesiology. 1999 Dec;91(6):1834-43. doi: 10.1097/00000542-199912000-00038. PubMed PMID: 10598628.