My Bibliography

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Peredo AP, Tsinman TK, Bonnevie ED, Jiang X, Smith HE, Gullbrand SE, Dyment NA, Mauck RL. Developmental morphogens direct human induced pluripotent stem cells toward an annulus fibrosus-like cell phenotype. JOR Spine. 2024 Mar;7(1):e1313. doi: 10.1002/jsp2.1313. eCollection 2024 Mar. PubMed PMID: 38283179; PubMed Central PMCID: PMC10810760.

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Muir VG, Fainor M, Orozco BS, Hilliard RL, Boyes M, Smith HE, Mauck RL, Schaer TP, Burdick JA, Gullbrand SE. Injectable Radiopaque Hyaluronic Acid Granular Hydrogels for Intervertebral Disc Repair. Adv Healthc Mater. 2023 Dec 23;:e2303326. doi: 10.1002/adhm.202303326. [Epub ahead of print] PubMed PMID: 38142300; PubMed Central PMCID: PMC11193841.

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Fainor M, Orozco BS, Muir VG, Mahindroo S, Gupta S, Mauck RL, Burdick JA, Smith HE, Gullbrand SE. Mechanical crosstalk between the intervertebral disc, facet joints, and vertebral endplate following acute disc injury in a rabbit model. JOR Spine. 2023 Dec;6(4):e1287. doi: 10.1002/jsp2.1287. eCollection 2023 Dec. PubMed PMID: 38156057; PubMed Central PMCID: PMC10751980.

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Peredo AP, Gullbrand SE, Friday CS, Orozco BS, Dehghani B, Jenk AC, Bonnevie ED, Hilliard RL, Zlotnick HM, Dodge GR, Lee D, Engiles JB, Hast MW, Schaer TP, Smith HE, Mauck RL. Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model. Sci Transl Med. 2023 Nov 15;15(722):eadf1690. doi: 10.1126/scitranslmed.adf1690. Epub 2023 Nov 15. PubMed PMID: 37967202; PubMed Central PMCID: PMC10812087.

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Levis H, Weston J, Austin B, Larsen B, Ginley-Hidinger M, Gullbrand SE, Lawrence B, Bowles RD. Multiplex gene editing to promote cell survival using low-pH clustered regularly interspaced short palindromic repeats activation (CRISPRa) gene perturbation. Cytotherapy. 2023 Oct;25(10):1069-1079. doi: 10.1016/j.jcyt.2023.05.001. Epub 2023 May 27. PubMed PMID: 37245150; PubMed Central PMCID: PMC10527564.

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Fainor M, Mahindroo S, Betz KR, Augustin J, Smith HE, Mauck RL, Gullbrand SE. A Tunable Calcium Phosphate Coating to Drive in vivo Osseointegration of Composite Engineered Tissues. Cells Tissues Organs. 2023;212(5):383-398. doi: 10.1159/000528965. Epub 2023 Mar 24. PubMed PMID: 36966531; PubMed Central PMCID: PMC10616759.

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Gupta S, Xiao R, Fainor M, Mauck RL, Smith HE, Gullbrand SE. Level dependent alterations in human facet cartilage mechanics and bone morphometry with spine degeneration. J Orthop Res. 2023 Mar;41(3):674-683. doi: 10.1002/jor.25407. Epub 2022 Jul 9. PubMed PMID: 35770853; PubMed Central PMCID: PMC9800647.

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Capogna EA, Brown E, Walrath E, Furst W, Dong Q, Zhou CM, Gullbrand SE, Vo NV, Sowa GA, Ledet EH. ISSLS Prize in Bioengineering Science 2022: low rate cyclic loading as a therapeutic strategy for intervertebral disc regeneration. Eur Spine J. 2022 May;31(5):1088-1098. doi: 10.1007/s00586-022-07239-2. Epub 2022 May 6. PubMed PMID: 35524071.

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Qazi TH, Wu J, Muir VG, Weintraub S, Gullbrand SE, Lee D, Issadore D, Burdick JA. Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion. Adv Mater. 2022 Mar;34(12):e2109194. doi: 10.1002/adma.202109194. Epub 2022 Jan 24. PubMed PMID: 34932833; PubMed Central PMCID: PMC8957565.

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Driscoll N, Erickson B, Murphy BB, Richardson AG, Robbins G, Apollo NV, Mentzelopoulos G, Mathis T, Hantanasirisakul K, Bagga P, Gullbrand SE, Sergison M, Reddy R, Wolf JA, Chen HI, Lucas TH, Dillingham TR, Davis KA, Gogotsi Y, Medaglia JD, Vitale F. MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation. Sci Transl Med. 2021 Sep 22;13(612):eabf8629. doi: 10.1126/scitranslmed.abf8629. Epub 2021 Sep 22. PubMed PMID: 34550728; PubMed Central PMCID: PMC8722432.

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Peredo AP, Gullbrand SE, Smith HE, Mauck RL. Putting the Pieces in Place: Mobilizing Cellular Players to Improve Annulus Fibrosus Repair. Tissue Eng Part B Rev. 2021 Aug;27(4):295-312. doi: 10.1089/ten.TEB.2020.0196. Epub 2020 Oct 19. Review. PubMed PMID: 32907498; PubMed Central PMCID: PMC10799291.

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Dahia CL, Engiles JB, Gullbrand SE, Iatridis JC, Lai A, Le Maitre CL, Lotz JC, Masuda K, Séguin CA, Tryfonidou MA. A perspective on the ORS Spine Section initiative to develop a multi-species JOR Spine histopathology series. JOR Spine. 2021 Jun;4(2):e1165. doi: 10.1002/jsp2.1165. eCollection 2021 Jun. PubMed PMID: 34337339; PubMed Central PMCID: PMC8313167.

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Gullbrand SE, Ashinsky BG, Lai A, Gansau J, Crowley J, Cunha C, Engiles JB, Fusellier M, Muehleman C, Pelletier M, Presciutti S, Schol J, Takeoka Y, Yurube T, Zhang Y, Masuda K, Iatridis JC. Development of a standardized histopathology scoring system for intervertebral disc degeneration and regeneration in rabbit models-An initiative of the ORSspine section. JOR Spine. 2021 Jun;4(2):e1147. doi: 10.1002/jsp2.1147. eCollection 2021 Jun. PubMed PMID: 34337334; PubMed Central PMCID: PMC8313151.

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Lai A, Gansau J, Gullbrand SE, Crowley J, Cunha C, Dudli S, Engiles JB, Fusellier M, Goncalves RM, Nakashima D, Okewunmi J, Pelletier M, Presciutti SM, Schol J, Takeoka Y, Yang S, Yurube T, Zhang Y, Iatridis JC. Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section. JOR Spine. 2021 Jun;4(2):e1150. doi: 10.1002/jsp2.1150. eCollection 2021 Jun. PubMed PMID: 34337335; PubMed Central PMCID: PMC8313153.

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Ashinsky BG, Gullbrand SE, Wang C, Bonnevie ED, Han L, Mauck RL, Smith HE. Degeneration alters structure-function relationships at multiple length-scales and across interfaces in human intervertebral discs. J Anat. 2021 Apr;238(4):986-998. doi: 10.1111/joa.13349. Epub 2020 Nov 17. PubMed PMID: 33205444; PubMed Central PMCID: PMC7930769.

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Ashinsky B, Smith HE, Mauck RL, Gullbrand SE. Intervertebral disc degeneration and regeneration: a motion segment perspective. Eur Cell Mater. 2021 Mar 24;41:370-380. doi: 10.22203/eCM.v041a24. Review. PubMed PMID: 33763848; PubMed Central PMCID: PMC8607668.

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Peredo AP, Gullbrand SE, Mauck RL, Smith HE. A challenging playing field: Identifying the endogenous impediments to annulus fibrosus repair. JOR Spine. 2021 Mar;4(1):e1133. doi: 10.1002/jsp2.1133. eCollection 2021 Mar. Review. PubMed PMID: 33778407; PubMed Central PMCID: PMC7984000.

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Zhang C, Gullbrand SE, Schaer TP, Boorman S, Elliott DM, Chen W, Dodge GR, Mauck RL, Malhotra NR, Smith LJ. Combined Hydrogel and Mesenchymal Stem Cell Therapy for Moderate-Severity Disc Degeneration in Goats. Tissue Eng Part A. 2021 Jan;27(1-2):117-128. doi: 10.1089/ten.TEA.2020.0103. Epub 2020 Aug 7. PubMed PMID: 32546053; PubMed Central PMCID: PMC7826444.

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Zlotnick HM, Clark AT, Gullbrand SE, Carey JL, Cheng XM, Mauck RL. Magneto-Driven Gradients of Diamagnetic Objects for Engineering Complex Tissues. Adv Mater. 2020 Dec;32(48):e2005030. doi: 10.1002/adma.202005030. Epub 2020 Oct 19. PubMed PMID: 33073437; PubMed Central PMCID: PMC7723011.

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Zhang C, Gullbrand SE, Schaer TP, Lau YK, Jiang Z, Dodge GR, Elliott DM, Mauck RL, Malhotra NR, Smith LJ. Inflammatory cytokine and catabolic enzyme expression in a goat model of intervertebral disc degeneration. J Orthop Res. 2020 Nov;38(11):2521-2531. doi: 10.1002/jor.24639. Epub 2020 Mar 3. PubMed PMID: 32091156; PubMed Central PMCID: PMC7483272.

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Kim DH, Martin JT, Gullbrand SE, Elliott DM, Smith LJ, Smith HE, Mauck RL. Fabrication, maturation, and implantation of composite tissue-engineered total discs formed from native and mesenchymal stem cell combinations. Acta Biomater. 2020 Sep 15;114:53-62. doi: 10.1016/j.actbio.2020.05.039. Epub 2020 Jun 4. PubMed PMID: 32505801; PubMed Central PMCID: PMC8633846.

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Ashinsky BG, Bonnevie ED, Mandalapu SA, Pickup S, Wang C, Han L, Mauck RL, Smith HE, Gullbrand SE. Intervertebral Disc Degeneration Is Associated With Aberrant Endplate Remodeling and Reduced Small Molecule Transport. J Bone Miner Res. 2020 Aug;35(8):1572-1581. doi: 10.1002/jbmr.4009. Epub 2020 Apr 2. PubMed PMID: 32176817; PubMed Central PMCID: PMC8207249.

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Ashinsky BG, Gullbrand SE, Bonnevie ED, Wang C, Kim DH, Han L, Mauck RL, Smith HE. Sacrificial Fibers Improve Matrix Distribution and Micromechanical Properties in a Tissue-Engineered Intervertebral Disc. Acta Biomater. 2020 Jul 15;111:232-241. doi: 10.1016/j.actbio.2020.05.019. Epub 2020 May 22. PubMed PMID: 32447064.

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Gullbrand SE, Kim DH, Ashinsky BG, Bonnevie ED, Smith HE, Mauck RL. Restoration of physiologic loading modulates engineered intervertebral disc structure and function in an in vivo model. JOR Spine. 2020 Jun;3(2):e1086. doi: 10.1002/jsp2.1086. eCollection 2020 Jun. PubMed PMID: 32613161; PubMed Central PMCID: PMC7323465.

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Ashinsky BG, Gullbrand SE, Bonnevie ED, Mandalapu SA, Wang C, Elliott DM, Han L, Mauck RL, Smith HE. Multiscale and multimodal structure-function analysis of intervertebral disc degeneration in a rabbit model. Osteoarthritis Cartilage. 2019 Dec;27(12):1860-1869. doi: 10.1016/j.joca.2019.07.016. Epub 2019 Aug 13. PubMed PMID: 31419488; PubMed Central PMCID: PMC6875634.

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Bonnevie ED, Gullbrand SE, Ashinsky BG, Tsinman TK, Elliott DM, Chao PG, Smith HE, Mauck RL. Aberrant mechanosensing in injured intervertebral discs as a result of boundary-constraint disruption and residual-strain loss. Nat Biomed Eng. 2019 Dec;3(12):998-1008. doi: 10.1038/s41551-019-0458-4. Epub 2019 Oct 14. PubMed PMID: 31611678; PubMed Central PMCID: PMC6899202.

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Gullbrand SE, Ashinsky BG, Bonnevie ED, Kim DH, Engiles JB, Smith LJ, Elliott DM, Schaer TP, Smith HE, Mauck RL. Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc. Sci Transl Med. 2018 Nov 21;10(468). doi: 10.1126/scitranslmed.aau0670. PubMed PMID: 30463917; PubMed Central PMCID: PMC7380504.

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Piazza M, Peck SH, Gullbrand SE, Bendigo JR, Arginteanu T, Zhang Y, Smith HE, Malhotra NR, Smith LJ. Quantitative MRI correlates with histological grade in a percutaneous needle injury mouse model of disc degeneration. J Orthop Res. 2018 Oct;36(10):2771-2779. doi: 10.1002/jor.24028. Epub 2018 May 24. PubMed PMID: 29687490; PubMed Central PMCID: PMC6200662.

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Gullbrand SE, Smith LJ, Smith HE, Mauck RL. Promise, progress, and problems in whole disc tissue engineering. JOR Spine. 2018 Jun;1(2):e1015. doi: 10.1002/jsp2.1015. eCollection 2018 Jun. Review. PubMed PMID: 31463442; PubMed Central PMCID: PMC6686799.

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Gullbrand SE, Kim DH, Bonnevie E, Ashinsky BG, Smith LJ, Elliott DM, Mauck RL, Smith HE. Towards the scale up of tissue engineered intervertebral discs for clinical application. Acta Biomater. 2018 Apr 1;70:154-164. doi: 10.1016/j.actbio.2018.01.050. Epub 2018 Feb 8. PubMed PMID: 29427744; PubMed Central PMCID: PMC7593900.

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Martin JT, Gullbrand SE, Fields AJ, Purmessur D, Diwan AD, Oxland TR, Chiba K, Guilak F, Hoyland JA, Iatridis JC. Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine. JOR Spine. 2018 Mar;1(1):e1006. doi: 10.1002/jsp2.1006. Epub 2018 Mar 23. PubMed PMID: 29770804; PubMed Central PMCID: PMC5944392.

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Martin JT, Gullbrand SE, Kim DH, Ikuta K, Pfeifer CG, Ashinsky BG, Smith LJ, Elliott DM, Smith HE, Mauck RL. In Vitro Maturation and In Vivo Integration and Function of an Engineered Cell-Seeded Disc-like Angle Ply Structure (DAPS) for Total Disc Arthroplasty. Sci Rep. 2017 Nov 17;7(1):15765. doi: 10.1038/s41598-017-15887-4. PubMed PMID: 29150639; PubMed Central PMCID: PMC5693867.

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Gullbrand SE, Schaer TP, Agarwal P, Bendigo JR, Dodge GR, Chen W, Elliott DM, Mauck RL, Malhotra NR, Smith LJ. Translation of an injectable triple-interpenetrating-network hydrogel for intervertebral disc regeneration in a goat model. Acta Biomater. 2017 Sep 15;60:201-209. doi: 10.1016/j.actbio.2017.07.025. Epub 2017 Jul 19. PubMed PMID: 28735027; PubMed Central PMCID: PMC5688915.

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Martin JT, Gullbrand SE, Mohanraj B, Ashinsky BG, Kim DH, Ikuta K, Elliott DM, Smith LJ, Mauck RL, Smith HE. (*) Optimization of Preculture Conditions to Maximize the In Vivo Performance of Cell-Seeded Engineered Intervertebral Discs. Tissue Eng Part A. 2017 Sep;23(17-18):923-934. doi: 10.1089/ten.tea.2016.0491. Epub 2017 Apr 19. PubMed PMID: 28426371; PubMed Central PMCID: PMC5610389.

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Sala RL, Kwon MY, Kim M, Gullbrand SE, Henning EA, Mauck RL, Camargo ER, Burdick JA. (*) Thermosensitive Poly(N-vinylcaprolactam) Injectable Hydrogels for Cartilage Tissue Engineering. Tissue Eng Part A. 2017 Sep;23(17-18):935-945. doi: 10.1089/ten.tea.2016.0464. Epub 2017 Apr 6. PubMed PMID: 28384053; PubMed Central PMCID: PMC5610396.

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Gullbrand SE, Malhotra NR, Schaer TP, Zawacki Z, Martin JT, Bendigo JR, Milby AH, Dodge GR, Vresilovic EJ, Elliott DM, Mauck RL, Smith LJ. A large animal model that recapitulates the spectrum of human intervertebral disc degeneration. Osteoarthritis Cartilage. 2017 Jan;25(1):146-156. doi: 10.1016/j.joca.2016.08.006. Epub 2016 Aug 26. PubMed PMID: 27568573; PubMed Central PMCID: PMC5182186.

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Gullbrand SE, Ashinsky BG, Martin JT, Pickup S, Smith LJ, Mauck RL, Smith HE. Correlations between quantitative T2 and T1ρ MRI, mechanical properties and biochemical composition in a rabbit lumbar intervertebral disc degeneration model. J Orthop Res. 2016 Aug;34(8):1382-8. doi: 10.1002/jor.23269. Epub 2016 Aug 10. PubMed PMID: 27105019; PubMed Central PMCID: PMC7398583.

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Gullbrand SE, Peterson J, Ahlborn J, Mastropolo R, Fricker A, Roberts TT, Abousayed M, Lawrence JP, Glennon JC, Ledet EH. ISSLS Prize Winner: Dynamic Loading-Induced Convective Transport Enhances Intervertebral Disc Nutrition. Spine (Phila Pa 1976). 2015 Aug 1;40(15):1158-64. doi: 10.1097/BRS.0000000000001012. PubMed PMID: 26222661.

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Gullbrand SE, Peterson J, Mastropolo R, Roberts TT, Lawrence JP, Glennon JC, DiRisio DJ, Ledet EH. Low rate loading-induced convection enhances net transport into the intervertebral disc in vivo. Spine J. 2015 May 1;15(5):1028-33. doi: 10.1016/j.spinee.2014.12.003. Epub 2014 Dec 9. PubMed PMID: 25500262.

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Gullbrand SE, Peterson J, Mastropolo R, Lawrence JP, Lopes L, Lotz J, Ledet EH. Drug-induced changes to the vertebral endplate vasculature affect transport into the intervertebral disc in vivo. J Orthop Res. 2014 Dec;32(12):1694-700. doi: 10.1002/jor.22716. Epub 2014 Sep 3. PubMed PMID: 25185989.