NCRUPAR non-protein coding RNA, upstream of F2R/PAR1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: NCRUPARprovided by HGNC
Official Full Name: non-protein coding RNA, upstream of F2R/PAR1provided by HGNC
Primary source: HGNC:HGNC:37153
See related: AllianceGenome:HGNC:37153
Gene type: ncRNA
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: ncR-uPAR; NCRNA00193
Summary: This non-coding RNA gene has been reported to have a positive regulatory affect during embryogenesis on the adjacent coagulation factor II (thrombin) receptor gene by Madamanchi et. al (PMID:12084570). [provided by RefSeq, Aug 2012]
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Genomic context

Location:: 5q13.3

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	5	NC_000005.10 (76712403..76712888)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	5	NC_060929.1 (77194265..77194747)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	5	NC_000005.9 (76008228..76008713)

Chromosome 5 - NC_000005.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Long non-coding RNA ncRuPAR regulates gastric cancer cell proliferation and apoptosis via phosphoinositide 3-kinase/protein kinase B signaling.
Title: Long non-coding RNA ncRuPAR regulates gastric cancer cell proliferation and apoptosis via phosphoinositide 3-kinase/protein kinase B signaling.
Downregulation of ncRuPAR is associated with colorectal cancer.
Title: Downregulation of a long noncoding RNA-ncRuPAR contributes to tumor inhibition in colorectal cancer.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Gene Ontology Provided by GOA

Process	Evidence Code	Pubs
involved_in positive regulation of gene expression	IEA Inferred from Electronic Annotation more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.