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    tipD autophagy protein 16 [ Dictyostelium discoideum AX4 ]

    Gene ID: 8619939, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tipD
    Official Full Name
    autophagy protein 16
    Primary source
    dictyBase:DDB_G0275323
    Locus tag
    DDB_G0275323
    See related
    AmoebaDB:DDB_G0275323; VEuPathDB:DDB_G0275323
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Dictyostelium discoideum AX4 (strain: AX4)
    Lineage
    Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales; Dictyosteliaceae; Dictyostelium
    Old locus tag
    DDBDRAFT_0202565; DDBDRAFT_0215341; DDB_0202565; DDB_0215341
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_007088.5 (5406103..5408018)

    Chromosome 2 - NC_007088.5Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene sigma adaptin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007088.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by dictyBase

    Function Evidence Code Pubs
    enables Atg8-family ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-membrane adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in autophagosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in autophagosome maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within culmination involved in sorocarp development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in macroautophagy ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within phagocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pinocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sorocarp development HMP PubMed 
    Component Evidence Code Pubs
    part_of Atg12-Atg5-Atg16 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Atg12-Atg5-Atg16 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of Atg12-Atg5-Atg16 complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in autophagosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular matrix HDA PubMed 
    is_active_in phagophore assembly site membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    autophagy protein 16

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007088.5 Reference assembly

      Range
      5406103..5408018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_638581.1 → XP_643673.1  autophagy protein 16 [Dictyostelium discoideum AX4]

      See identical proteins and their annotated locations for XP_643673.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O15736, Q553S4
      Conserved Domains (4) summary
      COG2319
      Location:313 → 612
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:317 → 612
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08614
      Location:47 → 254
      ATG16; Autophagy protein 16 (ATG16)
      sd00039
      Location:327 → 364
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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