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    CIN10 Cin10p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851995, updated on 2-Nov-2024

    Summary

    Official Symbol
    CIN10
    Official Full Name
    Cin10p
    Primary source
    SGD:S000002795
    Locus tag
    YDR387C
    See related
    AllianceGenome:SGD:S000002795; FungiDB:YDR387C; VEuPathDB:YDR387C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol import across plasma membrane. Located in fungal-type vacuole membrane. Orthologous to human SLC2A13 (solute carrier family 2 member 13). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See CIN10 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1248154..1249821, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene elongation factor 2 Neighboring gene Mus81p Neighboring gene amphiphysin Neighboring gene GTPase-activating protein SAC7

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables myo-inositol:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in myo-inositol import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in myo-inositol transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in polyol transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in fungal-type vacuole membrane HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    Cin10p
    NP_010675.3
    • Putative transporter; member of the sugar porter family; non-essential gene; overexpression results in elevated colony sectoring, an indicator of chromosomal instability

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1248154..1249821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180695.3NP_010675.3  TPA: Cin10p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010675.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT21, Q04162
      UniProtKB/TrEMBL
      B3LFR3, C7GSD5, C8Z5V1, N1P741
      Conserved Domains (1) summary
      cd17360
      Location:45528
      MFS_HMIT_like; H(+)-myo-inositol cotransporter and similar transporters of the Major Facilitator Superfamily