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    PET100 Pet100p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851651, updated on 2-Nov-2024

    Summary

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    Official Symbol
    PET100
    Official Full Name
    Pet100p
    Primary source
    SGD:S000002486
    Locus tag
    YDR079W
    See related
    AllianceGenome:SGD:S000002486; FungiDB:YDR079W; VEuPathDB:YDR079W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables unfolded protein binding activity. Involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See PET100 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (603064..603399)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Sed1p Neighboring gene Shu2p Neighboring gene TFIIH complex subunit TFB5 Neighboring gene Vps41p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of PET100, a gene required for the assembly of yeast cytochrome c oxidase. Church C, et al. J Biol Chem, 1996 Aug 2. PMID 8702496
    2. Structure and function of Pet100p, a molecular chaperone required for the assembly of cytochrome c oxidase in Saccharomyces cerevisiae. Forsha D, et al. Biochem Soc Trans, 2001 Aug. PMID 11498004
    3. A role for Pet100p in the assembly of yeast cytochrome c oxidase: interaction with a subassembly that accumulates in a pet100 mutant. Church C, et al. J Biol Chem, 2005 Jan 21. PMID 15507444
    4. Nutrient Control of Yeast Gametogenesis Is Mediated by TORC1, PKA and Energy Availability. Weidberg H, et al. PLoS Genet, 2016 Jun. PMID 27272508, Free PMC Article
    5. Metabolism of glucose activates TORC1 through multiple mechanisms in Saccharomyces cerevisiae. Alfatah M, et al. Cell Rep, 2023 Oct 31. PMID 37792530

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Pet100p functions in the holocytochrome c oxidase pathway to facilitate the interaction(s) between Complex A' and other cytochrome c oxidase subassemblies and subunits
      Title: A role for Pet100p in the assembly of yeast cytochrome c oxidase: interaction with a subassembly that accumulates in a pet100 mutant.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables unfolded protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial cytochrome c oxidase assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial cytochrome c oxidase assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pet100p
    NP_010364.1
    • Chaperone that facilitates the assembly of cytochrome c oxidase; integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      603064..603399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180387.1 → NP_010364.1  TPA: Pet100p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010364.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS65, P38958
      UniProtKB/TrEMBL
      A6ZY44, B3LGJ1, C7GVQ8, C8Z4Z6, G2WAI3, N1P846
      Conserved Domains (1) summary
      pfam09803
      Location:15 → 78
      Pet100
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38958.1

    Gene LinkOut

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