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    RK2 receptor kinase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842891, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RK2
    Official Full Name
    receptor kinase 2
    Primary source
    TAIR:AT1G65800
    Locus tag
    AT1G65800
    See related
    Araport:AT1G65800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS RECEPTOR KINASE 2; ARK2; AtARK2; F1E22.21; F1E22_21; receptor kinase 2
    Summary
    Encodes a putative receptor-like serine/threonine protein kinases that is similar to brassica self-incompatibility (S) locus. expressed in specifically in cotyledons, leaves, and sepals, in correlation with the maturation of these structures. Together with AtPUB9, it is required for auxin-mediated lateral root development under phosphate-starved conditions.
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    Genomic context

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    See RK2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (24472873..24476891)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene receptor kinase 1 Neighboring gene ncRNA Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene microsomal glutathione s-transferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A superfamily of S locus-related sequences in Arabidopsis: diverse structures and expression patterns. Dwyer KG, et al. Plant Cell, 1994 Dec. PMID 7866027, Free PMC Article
    2. Receptor-like protein kinase 2 (RPK 2) is a novel factor controlling anther development in Arabidopsis thaliana. Mizuno S, et al. Plant J, 2007 Jun. PMID 17419837
    3. Interactions between the S-domain receptor kinases and AtPUB-ARM E3 ubiquitin ligases suggest a conserved signaling pathway in Arabidopsis. Samuel MA, et al. Plant Physiol, 2008 Aug. PMID 18552232, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mutating ARK2 impairs normal pollen maturation and anther dehiscence due to disruption of key metabolic pathways.
      Title: Receptor-like protein kinase 2 (RPK 2) is a novel factor controlling anther development in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105253.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane receptor protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell surface receptor protein serine/threonine kinase signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in recognition of pollen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    receptor kinase 2
    NP_176756.1
    • receptor kinase 2 (RK2); CONTAINS InterPro DOMAIN/s: Curculin-like (mannose-binding) lectin (InterPro:IPR001480), Apple-like (InterPro:IPR003609), PAN-2 domain (InterPro:IPR013227), Protein kinase, ATP binding site (InterPro:IPR017441), S-locus receptor kinase, C-terminal (InterPro:IPR021820), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), S-locus glycoprotein (InterPro:IPR000858), S-locus, receptor kinase (InterPro:IPR022126), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: receptor kinase 1 (TAIR:AT1G65790.1); Has 122202 Blast hits to 120473 proteins in 4562 species: Archae - 111; Bacteria - 13838; Metazoa - 44423; Fungi - 10348; Plants - 34995; Viruses - 424; Other Eukaryotes - 18063 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24472873..24476891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334222.1 → NP_001322917.1  receptor kinase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVI8

    2. NM_105253.2 → NP_176756.1  receptor kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176756.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WL12, Q9S972, Q9SHX7
      UniProtKB/TrEMBL
      A0A5S9WQ48
      Conserved Domains (7) summary
      smart00108
      Location:35 → 156
      B_lectin; Bulb-type mannose-specific lectin
      cd00028
      Location:35 → 157
      B_lectin; Bulb-type mannose-specific lectin. The domain contains a three-fold internal repeat (beta-prism architecture). The consensus sequence motif QXDXNXVXY is involved in alpha-D-mannose recognition. Lectins are carbohydrate-binding proteins which specifically ...
      pfam11883
      Location:800 → 847
      DUF3403; Domain of unknown function (DUF3403)
      cd14066
      Location:529 → 798
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      pfam00954
      Location:216 → 325
      S_locus_glycop; S-locus glycoprotein domain
      pfam08276
      Location:347 → 411
      PAN_2; PAN-like domain
      pfam12398
      Location:472 → 513
      DUF3660; Receptor serine/threonine kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9S972.2

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