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    DGL1 dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836801, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DGL1
    Official Full Name
    dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein
    Primary source
    TAIR:AT5G66680
    Locus tag
    AT5G66680
    See related
    Araport:AT5G66680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DEFECTIVE GLYCOSYLATION; MSN2.7; MSN2_7
    Summary
    Encodes a protein ortholog of human SOT48 or yeast WBP1, an essential protein subunit of the oligosaccharyltransferase (OST) complex, which is responsible for the transfer in the ER of the N-linked glycan precursor onto Asn residues of candidate proteins.
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    Genomic context

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    See DGL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Sequence:
    Chromosome: 5; NC_003076.8 (26617399..26620704, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transmembrane protein, putative (DUF677) Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene homeobox 53

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutants in DEFECTIVE GLYCOSYLATION, an Arabidopsis homolog of an oligosaccharyltransferase complex subunit, show protein underglycosylation and defects in cell differentiation and growth. Lerouxel O, et al. Plant J, 2005 May. PMID 15860005
    2. Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions. Pendle AF, et al. Mol Biol Cell, 2005 Jan. PMID 15496452, Free PMC Article
    3. Arabidopsis cell wall proteome defined using multidimensional protein identification technology. Bayer EM, et al. Proteomics, 2006 Jan. PMID 16287169
    4. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    5. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DGL1 is involved in N-linked glycosylation, cell growth and differentiation in plants.[DGL1]
      Title: Mutants in DEFECTIVE GLYCOSYLATION, an Arabidopsis homolog of an oligosaccharyltransferase complex subunit, show protein underglycosylation and defects in cell differentiation and growth.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_126066.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    NOT involved_in cellulose biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein N-linked glycosylation via asparagine IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleolus HDA PubMed 
    part_of oligosaccharyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in plant-type cell wall HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein
    NP_569038.1
    • DEFECTIVE GLYCOSYLATION (DGL1); FUNCTIONS IN: dolichyl-diphosphooligosaccharide-protein glycotransferase activity; INVOLVED IN: plant-type cell wall organization, protein amino acid N-linked glycosylation via asparagine, unidimensional cell growth; LOCATED IN: in 8 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit (InterPro:IPR005013); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26617399..26620704 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126066.4 → NP_569038.1  dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_569038.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LDT6, Q944K2, Q94CD6, Q9LVR2
      UniProtKB/TrEMBL
      A0A178UHG1, A0A5S9YI53
      Conserved Domains (1) summary
      pfam03345
      Location:43 → 437
      DDOST_48kD; Oligosaccharyltransferase 48 kDa subunit beta
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q944K2.1

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