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    ERD (early-responsive to dehydration stress) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828301, updated on 18-Sep-2024

    Summary

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    Official Full Name
    ERD (early-responsive to dehydration stress) family protein
    Primary source
    TAIR:AT4G22120
    Locus tag
    AT4G22120
    See related
    Araport:AT4G22120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1N20.220; F1N20_220
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (11715607..11719873, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene GroES-like zinc-binding dehydrogenase family protein Neighboring gene SCR-like 14 Neighboring gene STRUBBELIG-receptor family 8 Neighboring gene PHD finger family protein / bromo-adjacent homology (BAH) domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2. Liu X, et al. Nat Commun, 2018 Nov 29. PMID 30498218, Free PMC Article
    2. DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes. Hou C, et al. Cell Res, 2014 May. PMID 24503647, Free PMC Article
    3. OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels. Murthy SE, et al. Elife, 2018 Nov 1. PMID 30382938, Free PMC Article
    4. Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Nühse TS, et al. Mol Cell Proteomics, 2003 Nov. PMID 14506206
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001084956.2
    NM_001125555.2
    NM_001125556.2
    NM_001125557.1
    NM_001203867.2
    NM_118333.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium-activated cation channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mechanosensitive monoatomic ion channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic cation transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ERD (early-responsive to dehydration stress) family protein
    NP_001078425.1
    • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 1475 Blast hits to 1296 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 185; Fungi - 716; Plants - 435; Viruses - 0; Other Eukaryotes - 139 (source: NCBI BLink).
    NP_001119027.1
    • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001119028.1
    • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001119029.1
    • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001190796.1
    • ERD (early-responsive to dehydration stress) family protein; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1).
    NP_193943.2
    • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 1475 Blast hits to 1296 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 185; Fungi - 716; Plants - 435; Viruses - 0; Other Eukaryotes - 139 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11715607..11719873 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118333.5 → NP_193943.2  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193943.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A097NUP4, O65460, Q56YV1, Q5XEZ5
      UniProtKB/TrEMBL
      A0A178UVB9, A0A5S9XV59, A0A654FRM3
      Conserved Domains (2) summary
      COG5594
      Location:3 → 680
      COG5594; Uncharacterized integral membrane protein [Function unknown]
      pfam02714
      Location:374 → 645
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

    2. NM_001203867.2 → NP_001190796.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190796.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A097NUP4, O65460, Q56YV1, Q5XEZ5
      UniProtKB/TrEMBL
      A0A178UVB9, A0A5S9XV59, A0A654FRM3
      Conserved Domains (2) summary
      COG5594
      Location:3 → 680
      COG5594; Uncharacterized integral membrane protein [Function unknown]
      pfam02714
      Location:374 → 645
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

    3. NM_001084956.2 → NP_001078425.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078425.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A097NUP4, O65460, Q56YV1, Q5XEZ5
      UniProtKB/TrEMBL
      A0A178UVB9, A0A5S9XV59, A0A654FRM3
      Conserved Domains (2) summary
      COG5594
      Location:3 → 680
      COG5594; Uncharacterized integral membrane protein [Function unknown]
      pfam02714
      Location:374 → 645
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

    4. NM_001125555.2 → NP_001119027.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119027.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A097NUP4, O65460, Q56YV1, Q5XEZ5
      UniProtKB/TrEMBL
      A0A178UVB9, A0A5S9XV59, A0A654FRM3
      Conserved Domains (2) summary
      COG5594
      Location:3 → 680
      COG5594; Uncharacterized integral membrane protein [Function unknown]
      pfam02714
      Location:374 → 645
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

    5. NM_001125556.2 → NP_001119028.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119028.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A097NUP4, O65460, Q56YV1, Q5XEZ5
      UniProtKB/TrEMBL
      A0A178UVB9, A0A5S9XV59, A0A654FRM3
      Conserved Domains (2) summary
      COG5594
      Location:3 → 680
      COG5594; Uncharacterized integral membrane protein [Function unknown]
      pfam02714
      Location:374 → 645
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

    6. NM_001125557.1 → NP_001119029.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119029.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A097NUP4, O65460, Q56YV1, Q5XEZ5
      UniProtKB/TrEMBL
      A0A178UVB9, A0A5S9XV59, A0A654FRM3
      Conserved Domains (2) summary
      COG5594
      Location:3 → 680
      COG5594; Uncharacterized integral membrane protein [Function unknown]
      pfam02714
      Location:374 → 645
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XEZ5.1

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