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    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822238, updated on 18-Sep-2024

    Summary

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    Official Full Name
    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
    Primary source
    TAIR:AT3G26340
    Locus tag
    AT3G26340
    See related
    Araport:AT3G26340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (9650316..9652936, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 71, subfamily B, polypeptide 36 Neighboring gene cytochrome P450, family 71, subfamily B, polypeptide 37 Neighboring gene proline-rich receptor-like kinase Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein S21 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes. Book AJ, et al. J Biol Chem, 2010 Aug 13. PMID 20516081, Free PMC Article
    2. Proteomic analysis of the 26S proteasome reveals its direct interaction with transit peptides of plastid protein precursors for their degradation. Sako K, et al. J Proteome Res, 2014 Jul 3. PMID 24846764
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113541.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome core complex, beta-subunit complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
    NP_189265.1
    • N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein; FUNCTIONS IN: endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: proteolysis involved in cellular protein catabolic process, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: guard cell; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: 20S proteasome beta subunit E1 (TAIR:AT1G13060.1); Has 6541 Blast hits to 6534 proteins in 612 species: Archae - 835; Bacteria - 512; Metazoa - 2083; Fungi - 1372; Plants - 865; Viruses - 0; Other Eukaryotes - 874 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9650316..9652936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113541.4 → NP_189265.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189265.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LIP2
      UniProtKB/TrEMBL
      A0A178VFG8, A0A5S9XG76, A0A7G2EQN0
      Conserved Domains (1) summary
      cd03761
      Location:58 → 245
      proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LIP2.1

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