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    [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818291, updated on 22-Aug-2024

    Summary

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    Primary source
    Araport:AT2G37150
    Locus tag
    AT2G37150
    See related
    TAIR:AT2G37150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T2N18.9; T2N18_9
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (15603142..15608587, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene GRF zinc finger protein Neighboring gene Peroxidase superfamily protein Neighboring gene Terpenoid synthases superfamily protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene ncRNA Neighboring gene plasma membrane intrinsic protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Homeostasis of Arabidopsis R protein RPS2 is negatively regulated by the RING-type E3 ligase MUSE16. Huang Y, et al. J Exp Bot, 2023 Mar 28. PMID 36655859
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001202766.1
    NM_001336627.1
    NM_001336628.1
    NM_001336629.1
    NM_001336630.1
    NM_001336631.1
    NM_001336632.1
    NM_001336633.1
    NM_001336634.1
    NM_001336637.1
    NM_001336638.1
    NM_179947.3
    NM_201889.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein autoubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of immune response IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RING/U-box superfamily protein
    NP_001189695.1
    • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; LOCATED IN: endomembrane system; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT4G34040.1).
    NP_001318370.1
    • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT4G34040.1); Has 8926 Blast hits to 8756 proteins in 294 species: Archae - 0; Bacteria - 12; Metazoa - 2086; Fungi - 596; Plants - 4930; Viruses - 41; Other Eukaryotes - 1261 (source: NCBI BLink).
    NP_973618.1
    • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT4G34040.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15603142..15608587 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336635.1 → NP_001324239.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. NM_001336636.1 → NP_001324232.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    3. NM_001336627.1 → NP_001318370.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    4. NM_001336634.1 → NP_001324240.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    5. NM_001336633.1 → NP_001324241.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    6. NM_001336638.1 → NP_001324231.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    7. NM_001336637.1 → NP_001324238.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    8. NM_201889.2 → NP_973618.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973618.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    9. NM_001336628.1 → NP_001324237.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    10. NM_001336629.1 → NP_001324233.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    11. NM_179947.3 → NP_850278.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850278.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A5S9X4Q8, A0A654F104, Q8VYL4
      Conserved Domains (3) summary
      COG5243
      Location:486 → 544
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:430 → 539
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:511 → 536
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    12. NM_001336631.1 → NP_001324235.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A1P8AZH1, A0A5S9X4Q8, A0A654F104
      Conserved Domains (3) summary
      COG5243
      Location:502 → 560
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:446 → 555
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:527 → 552
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    13. NM_001336632.1 → NP_001324234.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A1P8AZH1, A0A5S9X4Q8, A0A654F104
      Conserved Domains (3) summary
      COG5243
      Location:502 → 560
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:446 → 555
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:527 → 552
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    14. NM_001336630.1 → NP_001324236.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRU3, A0A1P8AZH1, A0A5S9X4Q8, A0A654F104
      Conserved Domains (3) summary
      COG5243
      Location:502 → 560
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      COG5540
      Location:446 → 555
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl17238
      Location:527 → 552
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    15. NM_001202766.1 → NP_001189695.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189695.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EG31, F4IQ07
      Conserved Domains (1) summary
      pfam13639
      Location:545 → 587
      zf-RING_2; Ring finger domain
    Nucleotide Protein
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