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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001319952.2 → NP_001306881.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate 5' exon and uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform a.
- Source sequence(s)
-
AK025175, AK307932, AL158847, CB159338
- UniProtKB/TrEMBL
-
A8K2J6
- Conserved Domains (3) summary
-
- cd11764
Location:392 → 444
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:1 → 120
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:461 → 526
- SAM_superfamily; SAM (Sterile alpha motif )
-
NM_024526.4 → NP_078802.2 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform c
See identical proteins and their annotated locations for NP_078802.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses two alternate in-frame splice junctions compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
- Source sequence(s)
-
AK025175, AK225235, AK290261, AW937714, BM797626, BM824107, CB159338, DA927692
- Consensus CDS
-
CCDS813.1
- UniProtKB/TrEMBL
-
A8K2J6
- Related
- ENSP00000354551.4, ENST00000361852.8
- Conserved Domains (3) summary
-
- cd11764
Location:425 → 477
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:25 → 154
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:494 → 559
- SAM_superfamily; SAM (Sterile alpha motif )
-
NM_133181.4 → NP_573444.2 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform b
See identical proteins and their annotated locations for NP_573444.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a.
- Source sequence(s)
-
AK292198, AY074930, BM737806, BM824107
- Consensus CDS
-
CCDS814.1
- UniProtKB/Swiss-Prot
- A8K833, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q8TE67, Q96E47, Q9H719
- UniProtKB/TrEMBL
-
A8K2J6
- Related
- ENSP00000355255.4, ENST00000361965.9
- Conserved Domains (3) summary
-
- cd11764
Location:455 → 507
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:25 → 154
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:524 → 589
- SAM_superfamily; SAM (Sterile alpha motif )
-
NM_139053.3 → NP_620641.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform a
See identical proteins and their annotated locations for NP_620641.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
- Source sequence(s)
-
BC012926, BM737806, BM824107, BP419077
- Consensus CDS
-
CCDS815.1
- UniProtKB/TrEMBL
-
A8K2J6
- Related
- ENSP00000358820.3, ENST00000369805.7
- Conserved Domains (3) summary
-
- cd11764
Location:456 → 508
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:25 → 154
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:525 → 590
- SAM_superfamily; SAM (Sterile alpha motif )
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
109750080..109763923 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047430380.1 → XP_047286336.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X8
-
XM_047430379.1 → XP_047286335.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X7
-
XM_011542134.4 → XP_011540436.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X5
- UniProtKB/TrEMBL
-
A8K2J6
- Conserved Domains (3) summary
-
- cd11764
Location:430 → 482
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:1 → 120
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:499 → 564
- SAM_superfamily; SAM (Sterile alpha motif )
-
XM_047430382.1 → XP_047286338.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X8
-
XM_047430384.1 → XP_047286340.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X5
-
XM_011542133.3 → XP_011540435.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X2
- UniProtKB/TrEMBL
-
A8K2J6
- Conserved Domains (3) summary
-
- cd11764
Location:463 → 515
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:25 → 154
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:532 → 597
- SAM_superfamily; SAM (Sterile alpha motif )
-
XM_017002329.3 → XP_016857818.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X6
- UniProtKB/TrEMBL
-
A8K2J6
-
XM_017002328.3 → XP_016857817.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X4
- UniProtKB/TrEMBL
-
A8K2J6
-
XM_011542132.3 → XP_011540434.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X1
- UniProtKB/TrEMBL
-
A8K2J6
- Conserved Domains (3) summary
-
- cd11764
Location:464 → 516
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:25 → 154
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:533 → 598
- SAM_superfamily; SAM (Sterile alpha motif )
-
XM_011542135.4 → XP_011540437.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X9
- UniProtKB/TrEMBL
-
A8K2J6
- Conserved Domains (3) summary
-
- cd11764
Location:400 → 452
- SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
- cd01210
Location:1 → 120
- PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
- cl15755
Location:469 → 534
- SAM_superfamily; SAM (Sterile alpha motif )
-
XM_047430369.1 → XP_047286325.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X5
-
XM_017002327.3 → XP_016857816.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X3
- UniProtKB/TrEMBL
-
A8K2J6
RNA
-
XR_007063682.1 RNA Sequence
-
XR_001737407.3 RNA Sequence
- Related
-
ENST00000472325.5
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
109760224..109774060 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054338727.1 → XP_054194702.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X8
-
XM_054338726.1 → XP_054194701.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X7
-
XM_054338724.1 → XP_054194699.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X5
-
XM_054338728.1 → XP_054194703.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X8
-
XM_054338730.1 → XP_054194705.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X5
-
XM_054338720.1 → XP_054194695.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X2
-
XM_054338725.1 → XP_054194700.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X6
-
XM_054338722.1 → XP_054194697.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X4
-
XM_054338719.1 → XP_054194694.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X1
-
XM_054338729.1 → XP_054194704.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X9
-
XM_054338723.1 → XP_054194698.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X5
-
XM_054338721.1 → XP_054194696.1 epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X3
RNA
-
XR_008486162.1 RNA Sequence
-
XR_008486163.1 RNA Sequence