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    sh3glb1a SH3-domain GRB2-like endophilin B1a [ Danio rerio (zebrafish) ]

    Gene ID: 792229, updated on 12-Sep-2024

    Summary

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    Official Symbol
    sh3glb1aprovided by ZNC
    Official Full Name
    SH3-domain GRB2-like endophilin B1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-89
    See related
    Ensembl:ENSDARG00000045294 AllianceGenome:ZFIN:ZDB-GENE-050417-89
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc55h11; fj98d09; sh3glb1; wu:fc55h11; wu:fj98d09; zgc:110259
    Summary
    Predicted to be involved in membrane organization. Predicted to act upstream of or within apoptotic process. Predicted to be located in Golgi membrane and mitochondrial outer membrane. Predicted to be active in membrane. Orthologous to human SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See sh3glb1a in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (28383322..28398100)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (28303840..28318941)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438353 Neighboring gene protein kinase, AMP-activated, gamma 2 non-catalytic subunit a Neighboring gene negative regulator of reactive oxygen species Neighboring gene F-box protein 45

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC110259

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    endophilin-B1a
    Names
    SH3-domain GRB2-like endophilin B1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017617.1 → NP_001017617.1  endophilin-B1a

      See identical proteins and their annotated locations for NP_001017617.1

      Status: PROVISIONAL

      Source sequence(s)
      BC092831
      UniProtKB/TrEMBL
      Q568J6
      Related
      ENSDARP00000018632.6, ENSDART00000018095.8
      Conserved Domains (2) summary
      cd11945
      Location:300 → 360
      SH3_Endophilin_B1; Src homology 3 domain of Endophilin-B1
      cl12013
      Location:21 → 249
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      28383322..28398100
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009297515.4 → XP_009295790.1  endophilin-B1a isoform X1

      UniProtKB/TrEMBL
      A0A8M3AW37
      Conserved Domains (2) summary
      cd11945
      Location:338 → 398
      SH3_Endophilin_B1; Src homology 3 domain of Endophilin-B1
      cl12013
      Location:21 → 287
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395180.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      52119..66942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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