U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    MIR215 microRNA 215 [ Gallus gallus (chicken) ]

    Gene ID: 777807, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Symbol
    MIR215provided by CGNC
    Full Name
    microRNA 215provided by CGNC
    Primary source
    CGNC:59092
    See related
    Ensembl:ENSGALG00010019456 miRBase:MI0001203
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    MIRN215; gga-mir-215
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MIR215 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (18494000..18494104)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (18407526..18407630)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene RAB3 GTPase activating non-catalytic protein subunit 2 Neighboring gene isoleucyl-tRNA synthetase 2, mitochondrial Neighboring gene uncharacterized LOC121113144 Neighboring gene microRNA 194-1 Neighboring gene 3'(2'), 5'-bisphosphate nucleotidase 1 Neighboring gene glutamyl-prolyl-tRNA synthetase

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Mir-215-5p induces autophagy by targeting PI3K and activating ROS-mediated MAPK pathways in cardiomyocytes of chicken. Cai J, et al. J Inorg Biochem, 2019 Apr. PMID 30684759
    2. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. International Chicken Genome Sequencing Consortium. Nature, 2004 Dec 9. PMID 15592404
    3. Birth and expression evolution of mammalian microRNA genes. Meunier J, et al. Genome Res, 2013 Jan. PMID 23034410, Free PMC Article
    4. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Other Names

    • microRNA mir-215

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_031427.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000062
      Related
      ENSGALT00010046989.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      18494000..18494104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      18407526..18407630
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.