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    USP48 ubiquitin specific peptidase 48 [ Gallus gallus (chicken) ]

    Gene ID: 769457, updated on 10-Oct-2024

    Summary

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    Official Symbol
    USP48provided by CGNC
    Official Full Name
    ubiquitin specific peptidase 48provided by CGNC
    Primary source
    CGNC:10544
    See related
    Ensembl:ENSGALG00010018251
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See USP48 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (6552494..6576987)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (6587504..6611985)

    Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene chymotrypsin like elastase family member 3B Neighboring gene heparan sulfate proteoglycan 2 Neighboring gene RAP1 GTPase activating protein 1 Neighboring gene alkaline phosphatase, biomineralization associated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 48
    Names
    deubiquitinating enzyme 48
    ubiquitin thioesterase 48
    ubiquitin thiolesterase 48
    ubiquitin-specific-processing protease 48
    NP_001073211.2
    XP_015152743.1
    XP_024998322.1
    XP_046759134.1
    XP_046759135.1
    XP_046759136.1
    XP_046759137.1
    XP_046787322.1
    XP_046787323.1
    XP_046787324.1
    XP_046787325.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079743.2 → NP_001073211.2  ubiquitin carboxyl-terminal hydrolase 48

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000329
      UniProtKB/Swiss-Prot
      Q5ZM45
      UniProtKB/TrEMBL
      A0A1D5P1U8
      Related
      ENSGALP00010026196.1, ENSGALT00010044072.1
      Conserved Domains (3) summary
      cd02668
      Location:90 → 417
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd01795
      Location:937 → 1032
      Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins
      cl12116
      Location:477 → 554
      DUSP; DUSP domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      6552494..6576987
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025142554.3 → XP_024998322.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X3

      UniProtKB/Swiss-Prot
      Q5ZM45
      Conserved Domains (3) summary
      cd02668
      Location:90 → 417
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam06337
      Location:481 → 552
      DUSP; DUSP domain
      cl00155
      Location:927 → 1027
      UBQ; Ubiquitin-like proteins

    2. XM_046903179.1 → XP_046759135.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X2

      UniProtKB/TrEMBL
      A0A1D5P1U8
      Related
      ENSGALP00010026204.1, ENSGALT00010044085.1

    3. XM_046903181.1 → XP_046759137.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X5

    4. XM_015297257.4 → XP_015152743.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YYT7
      Related
      ENSGALP00010026199.1, ENSGALT00010044077.1
      Conserved Domains (4) summary
      cd02668
      Location:90 → 417
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam00443
      Location:89 → 416
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam06337
      Location:481 → 552
      DUSP; DUSP domain
      cl00155
      Location:892 → 998
      UBQ; Ubiquitin-like proteins

    5. XM_046903180.1 → XP_046759136.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X4

    6. XM_046903178.1 → XP_046759134.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X1

      Related
      ENSGALP00010026192.1, ENSGALT00010044065.1

    RNA

    1. XR_005841379.2 RNA Sequence

    2. XR_001469818.4 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      6587504..6611985
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046931367.1 → XP_046787323.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X3

    2. XM_046931366.1 → XP_046787322.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X2

      UniProtKB/TrEMBL
      A0A1D5P1U8

    3. XM_046931368.1 → XP_046787324.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X5

    4. XM_046931369.1 → XP_046787325.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X6

    RNA

    1. XR_006936862.1 RNA Sequence

    2. XR_006936863.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5ZM45.1 GenPept UniProtKB/Swiss-Prot:Q5ZM45

    Gene LinkOut

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