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    PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718012, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PIK3R4provided by VGNC
    Official Full Name
    phosphoinositide-3-kinase regulatory subunit 4provided by VGNC
    Primary source
    VGNC:VGNC:84060
    See related
    Ensembl:ENSMMUG00000020294
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PIK3R4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (32993376..33067110, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (171227001..171303127)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene collagen type VI alpha 5 chain Neighboring gene collagen type VI alpha 6 chain Neighboring gene glutathione S-transferase omega-1 pseudogene Neighboring gene ATPase secretory pathway Ca2+ transporting 1 Neighboring gene cysteine and glycine-rich protein 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagy of peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in late endosome to vacuole transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein targeting to vacuole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in late endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus-vacuole junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphoinositide 3-kinase regulatory subunit 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      32993376..33067110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015132206.2 → XP_014987692.1  phosphoinositide 3-kinase regulatory subunit 4

      UniProtKB/TrEMBL
      F6WX07, H9FTP6, I0FR98
      Related
      ENSMMUP00000026707.3, ENSMMUT00000028545.4
      Conserved Domains (8) summary
      smart00320
      Location:1327 → 1358
      WD40; WD40 repeats
      smart00220
      Location:26 → 309
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG2319
      Location:991 → 1358
      WD40; WD40 repeat [General function prediction only]
      cd13980
      Location:25 → 320
      STKc_Vps15; Catalytic domain of the Serine/Threonine kinase, Vacuolar protein sorting-associated protein 15
      pfam07539
      Location:352 → 448
      DRIM; Down-regulated in metastasis
      sd00044
      Location:539 → 566
      HEAT; HEAT repeat [structural motif]
      sd00039
      Location:997 → 1040
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:985 → 1269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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