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    GNB4 G protein subunit beta 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709489, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GNB4provided by VGNC
    Official Full Name
    G protein subunit beta 4provided by VGNC
    Primary source
    VGNC:VGNC:72975
    Locus tag
    EGK_11879
    See related
    Ensembl:ENSMMUG00000004083
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    HG2B
    Orthologs
    human mouse all
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    Genomic context

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    See GNB4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (84537469..84592726, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (113806880..113863651)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 639 Neighboring gene mitofusin 1 Neighboring gene bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial pseudogene Neighboring gene CWF19-like protein 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor complex adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of heterotrimeric G-protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein subunit beta-4
    Names
    heterotrimeric guanine nucleotide-binding protein 2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261165.1 → NP_001248094.1  guanine nucleotide-binding protein subunit beta-4

      See identical proteins and their annotated locations for NP_001248094.1

      Status: PROVISIONAL

      Source sequence(s)
      JU476654
      UniProtKB/TrEMBL
      A0A8J8XL79, F6ZIZ9, F7G9I6, G7MJ90
      Related
      ENSMMUP00000005459.2, ENSMMUT00000005797.4
      Conserved Domains (2) summary
      cd00200
      Location:48 → 340
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:58 → 95
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      84537469..84592726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843312.1 → XP_028699145.1  guanine nucleotide-binding protein subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      F7G9I6
      Conserved Domains (2) summary
      cd00200
      Location:12 → 304
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:22 → 59
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials