U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    SNAP25 synaptosome associated protein 25 [ Homo sapiens (human) ]

    Gene ID: 6616, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SNAP25provided by HGNC
    Official Full Name
    synaptosome associated protein 25provided by HGNC
    Primary source
    HGNC:HGNC:11132
    See related
    Ensembl:ENSG00000132639 MIM:600322; AllianceGenome:HGNC:11132
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SUP; RIC4; SEC9; SNAP; CMS18; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2
    Summary
    Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
    Expression
    Restricted expression toward brain (RPKM 418.5) See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SNAP25 in Genome Data Viewer
    Location:
    20p12.2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (10218830..10307418)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (10261695..10350292)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (10199478..10288066)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene SNAP25 antisense RNA 1 Neighboring gene uncharacterized LOC105372524 Neighboring gene uncharacterized LOC124904959 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr20:10221152-10221653 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr20:10221654-10222154 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr20:10281144-10282061 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:10322076-10322299 Neighboring gene HIG1 hypoxia inducible domain family member 1A pseudogene 15 Neighboring gene ribosomal protein L23a pseudogene 6

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.
      Title: Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.
    2. The Role of SNAP-25 in Autism Spectrum Disorders Onset Patterns.
      Title: The Role of SNAP-25 in Autism Spectrum Disorders Onset Patterns.
    3. Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.
      Title: Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.
    4. Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.
      Title: Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.
    5. Role of SNAP25 on the occurrence and development of eosinophilic gastritis.
      Title: Role of SNAP25 on the occurrence and development of eosinophilic gastritis.
    6. Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility.
      Title: Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility.
    7. miR-23a-3p and miR-181a-5p modulate SNAP-25 expression.
      Title: miR-23a-3p and miR-181a-5p modulate SNAP-25 expression.
    8. Investigation of possible associations of the BDNF, SNAP-25 and SYN III genes with the neurocognitive measures: BDNF and SNAP-25 genes might be involved in attention domain, SYN III gene in executive function.
      Title: Investigation of possible associations of the BDNF, SNAP-25 and SYN III genes with the neurocognitive measures: BDNF and SNAP-25 genes might be involved in attention domain, SYN III gene in executive function.
    9. Role of SNAP-25 MnlI variant in impaired working memory and brain functions in attention deficit/hyperactivity disorder.
      Title: Role of SNAP-25 MnlI variant in impaired working memory and brain functions in attention deficit/hyperactivity disorder.
    10. Cerebrospinal Fluid Synaptosomal-Associated Protein 25 Levels in Patients with Alzheimer's Disease: A Meta-Analysis.
      Title: Cerebrospinal Fluid Synaptosomal-Associated Protein 25 Levels in Patients with Alzheimer's Disease: A Meta-Analysis.
    Submit: New GeneRIF Correction See all GeneRIFs (151)

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Congenital myasthenic syndrome 18
    MedGen: C4225364 OMIM: 616330 GeneReviews: Congenital Myasthenic Syndromes Overview
    		Compare labs

    EBI GWAS Catalog

    Description
    Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
    EBI GWAS Catalog
    Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.
    EBI GWAS Catalog

    Variation

    Go to the top of the page Help

    See Variation Viewer (GRCh37.p13)

    HIV-1 interactions

    Go to the top of the page Help

    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat HIV-1 Tat downregulates the pre-synaptic protein SNAP25 expression via neuronal mir-128 in primary cortical neurons PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • FLJ23079

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium-dependent protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables lipid binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables myosin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables syntaxin-1 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables syntaxin-1 binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables voltage-gated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in SNARE complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in associative learning IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chemical synaptic transmission NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in endosomal transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in locomotory behavior IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in long-term memory IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in long-term synaptic potentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neurotransmitter uptake NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in positive regulation of insulin secretion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in presynaptic dense core vesicle exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of insulin secretion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of neuron projection development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of synapse assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in synaptic vesicle docking NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in synaptic vesicle exocytosis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in synaptic vesicle fusion to presynaptic active zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptic vesicle priming IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of BLOC-1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SNARE complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of SNARE complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in axonal growth cone IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extrinsic component of presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in filopodium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in growth cone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in neuron projection ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in photoreceptor inner segment IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		  
    located_in presynaptic membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribbon synapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in specific granule membrane TAS
    Traceable Author Statement
    more info
    		  
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of synaptobrevin 2-SNAP-25-syntaxin-1a complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in tertiary granule membrane TAS
    Traceable Author Statement
    more info
    		  
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		  
    colocalizes_with vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of voltage-gated potassium channel complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    synaptosomal-associated protein 25
    Names
    resistance to inhibitors of cholinesterase 4 homolog
    synaptosomal-associated protein, 25kDa
    synaptosome associated protein 25kDa

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029626.1 RefSeqGene

      Range
      5002..93590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001322902.2 → NP_001309831.1  synaptosomal-associated protein 25 isoform SNAP25A

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13109.1
      UniProtKB/Swiss-Prot
      P60880
      Related
      ENSP00000516314.1, ENST00000706269.1
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    2. NM_001322903.2 → NP_001309832.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000508541.1, ENST00000691665.1
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    3. NM_001322904.2 → NP_001309833.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000510558.1, ENST00000693325.1
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    4. NM_001322905.2 → NP_001309834.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000510663.1, ENST00000689858.1
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    5. NM_001322906.2 → NP_001309835.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000508837.1, ENST00000685131.1
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    6. NM_001322907.2 → NP_001309836.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000510109.1, ENST00000691161.1
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    7. NM_001322908.2 → NP_001309837.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000510219.1, ENST00000687785.1
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    8. NM_001322909.2 → NP_001309838.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    9. NM_001322910.2 → NP_001309839.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    10. NM_001424415.1 → NP_001411344.1  synaptosomal-associated protein 25 isoform SNAP25A

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824

    11. NM_001424416.1 → NP_001411345.1  synaptosomal-associated protein 25 isoform SNAP25B

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000509759.1, ENST00000691353.1

    12. NM_003081.5 → NP_003072.2  synaptosomal-associated protein 25 isoform SNAP25A

      See identical proteins and their annotated locations for NP_003072.2

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13109.1
      UniProtKB/Swiss-Prot
      P60880
      Related
      ENSP00000307341.2, ENST00000304886.6
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    13. NM_130811.4 → NP_570824.1  synaptosomal-associated protein 25 isoform SNAP25B

      See identical proteins and their annotated locations for NP_570824.1

      Status: REVIEWED

      Source sequence(s)
      AL023913, AL354824
      Consensus CDS
      CCDS13110.1
      UniProtKB/Swiss-Prot
      B2RAU4, D3DW16, D3DW17, P13795, P36974, P60880, P70557, P70558, Q53EM2, Q5U0B5, Q8IXK3, Q96FM2, Q9BR45
      Related
      ENSP00000254976.3, ENST00000254976.7
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      10218830..10307418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017028022.2 → XP_016883511.1  synaptosomal-associated protein 25 isoform X2

      UniProtKB/Swiss-Prot
      P60880
      Conserved Domains (3) summary
      cd15885
      Location:143 → 201
      SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
      cd15894
      Location:10 → 82
      SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
      pfam00835
      Location:91 → 141
      SNAP-25; SNAP-25 family

    2. XM_047440391.1 → XP_047296347.1  synaptosomal-associated protein 25 isoform X3

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      10261695..10350292
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054323888.1 → XP_054179863.1  synaptosomal-associated protein 25 isoform X2

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P60880.1 GenPept UniProtKB/Swiss-Prot:P60880

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous