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    Otd1 orthodenticle-1 [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 641553, updated on 12-Apr-2024

    Summary

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    Gene symbol
    Otd1
    Gene description
    orthodenticle-1
    Locus tag
    TcasGA2_TC003354
    See related
    BEETLEBASE:TC003354
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Also known as
    oc; otd; otd-1; ocelliless
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    Genomic context

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    See Otd1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 1 NC_087394.1 (34553442..34599598, complement)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG3 NC_007418.3 (2022498..2068549)

    Chromosome 1 - NC_087394.1Genomic Context describing neighboring genes Neighboring gene mitochondrial inner membrane protease subunit 2 Neighboring gene KICSTOR complex protein ITFG2 Neighboring gene orthodenticle-2 Neighboring gene tyrosine-protein kinase-like otk Neighboring gene uncharacterized LOC107397482 Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene uncharacterized LOC103312267

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two orthodenticle-related genes in the short-germ beetle Tribolium castaneum. Li Y, et al. Dev Genes Evol, 1996 Jun. PMID 24173395
    2. The genes orthodenticle and hunchback substitute for bicoid in the beetle Tribolium. Schröder R. Nature, 2003 Apr 10. PMID 12687002
    3. Divergent functions of orthodenticle, empty spiracles and buttonhead in early head patterning of the beetle Tribolium castaneum (Coleoptera). Schinko JB, et al. Dev Biol, 2008 May 15. PMID 18407258
    4. Evolution of development: beyond bicoid. Lynch J, et al. Curr Biol, 2003 Jul 15. PMID 12867048
    5. BeetleBase in 2010: revisions to provide comprehensive genomic information for Tribolium castaneum. Kim HS, et al. Nucleic Acids Res, 2010 Jan. PMID 19820115, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Tc-orthodenticle1 (Tc-otd1) has a function in early regionalization of all segments formed during the blastoderm stage, and a later head patterning function similar to that in Drosophila.
      Title: Divergent functions of orthodenticle, empty spiracles and buttonhead in early head patterning of the beetle Tribolium castaneum (Coleoptera).
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    orthodenticle-1
    Names
    AUGUSTUS-3.0.2_03354
    GLEAN_03354

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039424.1 → NP_001034513.1  orthodenticle-1

      See identical proteins and their annotated locations for NP_001034513.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ223627
      UniProtKB/TrEMBL
      O46169
      Conserved Domains (1) summary
      pfam00046
      Location:131 → 183
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087394.1 Reference icTriCast1.1 Primary Assembly

      Range
      34553442..34599598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015977567.2 → XP_015833053.1  orthodenticle-1 isoform X3

      Conserved Domains (1) summary
      pfam00046
      Location:72 → 124
      Homeobox; Homeobox domain

    2. XM_008192467.3 → XP_008190689.1  orthodenticle-1 isoform X1

      See identical proteins and their annotated locations for XP_008190689.1

      UniProtKB/TrEMBL
      O46169
      Conserved Domains (1) summary
      pfam00046
      Location:131 → 183
      Homeobox; Homeobox domain

    3. XM_008192468.3 → XP_008190690.1  orthodenticle-1 isoform X2

      Conserved Domains (1) summary
      pfam00046
      Location:125 → 177
      Homeobox; Homeobox domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Research Materials