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    Gm14322 predicted gene 14322 [ Mus musculus (house mouse) ]

    Gene ID: 626802, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Gm14322provided by MGI
    Official Full Name
    predicted gene 14322provided by MGI
    Primary source
    MGI:MGI:3652185
    See related
    Ensembl:ENSMUSG00000078864 AllianceGenome:MGI:3652185
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in bladder adult (RPKM 3.4), cerebellum adult (RPKM 2.9) and 23 other tissues See more
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    Genomic context

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    Location:
    2 H4; 2 99.5 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (177400928..177415192)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (177759149..177773399)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 52573 Neighboring gene predicted gene 14324 Neighboring gene STARR-seq mESC enhancer starr_06687 Neighboring gene STARR-seq mESC enhancer starr_06688 Neighboring gene STARR-seq mESC enhancer starr_06690 Neighboring gene STARR-seq mESC enhancer starr_06691 Neighboring gene predicted gene 14325 Neighboring gene STARR-seq mESC enhancer starr_06692 Neighboring gene STARR-seq mESC enhancer starr_06693 Neighboring gene STARR-seq mESC enhancer starr_06694 Neighboring gene ribosomal protein S8, pseudogene 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC626802

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243903.1 → NP_001230832.1  uncharacterized protein LOC626802 isoform 1

      See identical proteins and their annotated locations for NP_001230832.1

      Status: VALIDATED

      Source sequence(s)
      AL935320, BC092145, CF735056
      Consensus CDS
      CCDS57202.1
      UniProtKB/TrEMBL
      A2AW66
      Related
      ENSMUSP00000136870.2, ENSMUST00000119838.9
      Conserved Domains (3) summary
      COG5048
      Location:138 → 347
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:133 → 153
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box

    2. NM_001324422.1 → NP_001311351.1  uncharacterized protein LOC626802 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL935320, BC092145, CF735056
      Conserved Domains (2) summary
      COG5048
      Location:106 → 315
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      177400928..177415192
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162439.1 → XP_036018332.1  uncharacterized protein LOC626802 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:106 → 315
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_011239952.4 → XP_011238254.1  uncharacterized protein LOC626802 isoform X1

      See identical proteins and their annotated locations for XP_011238254.1

      UniProtKB/TrEMBL
      A2AW66
      Conserved Domains (3) summary
      COG5048
      Location:138 → 347
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:133 → 153
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box

    3. XM_011239954.4 → XP_011238256.1  uncharacterized protein LOC626802 isoform X2

      See identical proteins and their annotated locations for XP_011238256.1

      Conserved Domains (2) summary
      COG5048
      Location:106 → 315
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_011239955.4 → XP_011238257.1  uncharacterized protein LOC626802 isoform X2

      See identical proteins and their annotated locations for XP_011238257.1

      Conserved Domains (2) summary
      COG5048
      Location:106 → 315
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_036162440.1 → XP_036018333.1  uncharacterized protein LOC626802 isoform X2

      Related
      ENSMUSP00000104570.4, ENSMUST00000108942.5
      Conserved Domains (2) summary
      COG5048
      Location:106 → 315
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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