ptger1b prostaglandin E receptor 1b (subtype EP1) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ptger1bprovided by ZNC
Official Full Name: prostaglandin E receptor 1b (subtype EP1)provided by ZNC
Primary source: ZFIN:ZDB-GENE-100922-278
See related: Ensembl:ENSDARG00000104847 AllianceGenome:ZFIN:ZDB-GENE-100922-278
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ptger1a
Summary: Enables prostaglandin E receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Orthologous to human PTGER1 (prostaglandin E receptor 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (13827749..13839353)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (13677846..13687326)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables prostaglandin E receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables prostaglandin E receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables thromboxane receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in inflammatory response	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cytosolic calcium ion concentration	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: prostaglandin E receptor 1b (subtype EP1)

Names: EP1a; prostaglandin E receptor 1, subtype EP1a; ptger1; zPRC1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001166333.1 → NP_001159805.1 prostaglandin E receptor 1b (subtype EP1)

See identical proteins and their annotated locations for NP_001159805.1

Status: PROVISIONAL

Source sequence(s)

GQ911587

UniProtKB/TrEMBL

A0A8M2BAZ6, D0EXE2

Related

ENSDARP00000136587.1, ENSDART00000159282.2

Conserved Domains (2) summary

pfam00001
Location:58 → 345

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:47 → 264

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007114.7 Reference GRCz11 Primary Assembly

Range

13827749..13839353

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005163745.5 → XP_005163802.1 prostaglandin E receptor 1b (subtype EP1) isoform X1

See identical proteins and their annotated locations for XP_005163802.1

UniProtKB/TrEMBL

A0A8M2BAZ6, D0EXE2

Conserved Domains (2) summary

pfam00001
Location:58 → 345

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:47 → 264

7tm_4; Olfactory receptor