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    Pdk1 Phosphoinositide-dependent kinase 1 [ Aedes aegypti (yellow fever mosquito) ]

    Gene ID: 5569001, updated on 23-May-2024

    Summary

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    Gene symbol
    Pdk1
    Gene description
    Phosphoinositide-dependent kinase 1
    See related
    VectorBase:AAEL007284
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Aedes aegypti
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Aedini; Aedes; Stegomyia
    Also known as
    AAEL007284
    Orthologs
    fruit fly all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    101 current AaegL5.0 (GCF_002204515.2) 3 NC_035109.1 (196315889..196328923, complement)

    Chromosome 3 - NC_035109.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC5569003 Neighboring gene muscle M-line assembly protein unc-89 Neighboring gene uncharacterized LOC110679701 Neighboring gene Myocardin-related transcription factor Neighboring gene acyl-CoA synthetase short-chain family member 3, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_035109.1 Chromosome 3 Reference AaegL5.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Description of the transcriptomes of immune response-activated hemocytes from the mosquito vectors Aedes aegypti and Armigeres subalbatus. Bartholomay LC, et al. Infect Immun, 2004 Jul. PMID 15213157, Free PMC Article
    2. The neurotranscriptome of the Aedes aegypti mosquito. Matthews BJ, et al. BMC Genomics, 2016 Jan 6. PMID 26738925, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-phosphoinositide-dependent protein kinase 1
    Names
    serine/threonine-protein kinase pk61c

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Aedes aegypti Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference AaegL5.0 Primary Assembly

    Genomic

    1. NC_035109.1 Reference AaegL5.0 Primary Assembly

      Range
      196315889..196328923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021850107.1 → XP_021705799.1  3-phosphoinositide-dependent protein kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A6I8T9W3
      Conserved Domains (2) summary
      pfam14593
      Location:110 → 213
      PH_3; PH domain
      cl21453
      Location:22 → 89
      PKc_like; Protein Kinases, catalytic domain

    2. XM_021850105.1 → XP_021705797.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1S4FGA4, Q172S2
      Conserved Domains (2) summary
      cd05581
      Location:22 → 305
      STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
      pfam14593
      Location:402 → 505
      PH_3; PH domain

    3. XM_001652603.2 → XP_001652653.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_001652653.1

      UniProtKB/TrEMBL
      A0A1S4FGA4, Q172S2
      Conserved Domains (2) summary
      cd05581
      Location:22 → 305
      STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
      pfam14593
      Location:402 → 505
      PH_3; PH domain

    4. XM_021850106.1 → XP_021705798.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1S4FGA4, Q172S2
      Conserved Domains (2) summary
      cd05581
      Location:22 → 305
      STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
      pfam14593
      Location:402 → 505
      PH_3; PH domain

    RNA

    1. XR_002501350.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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