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    Roc1a Regulator of cullins 1a [ Aedes aegypti (yellow fever mosquito) ]

    Gene ID: 5565270, updated on 23-May-2024

    Summary

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    Gene symbol
    Roc1a
    Gene description
    Regulator of cullins 1a
    See related
    VectorBase:AAEL004691
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Aedes aegypti
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Aedini; Aedes; Stegomyia
    Also known as
    AAEL004691
    Orthologs
    fruit fly all
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    Genomic context

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    See Roc1a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    101 current AaegL5.0 (GCF_002204515.2) 1 NC_035107.1 (118834052..118849786, complement)

    Chromosome 1 - NC_035107.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S28-like Neighboring gene otopetrin-2 Neighboring gene Fl(2)d-associated complex component Neighboring gene beta-1,4-mannosyltransferase egh

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_035107.1 Chromosome 1 Reference AaegL5.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti. Ribeiro JM, et al. BMC Genomics, 2007 Jan 4. PMID 17204158, Free PMC Article
    2. Description of the transcriptomes of immune response-activated hemocytes from the mosquito vectors Aedes aegypti and Armigeres subalbatus. Bartholomay LC, et al. Infect Immun, 2004 Jul. PMID 15213157, Free PMC Article
    3. The neurotranscriptome of the Aedes aegypti mosquito. Matthews BJ, et al. BMC Genomics, 2016 Jan 6. PMID 26738925, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cullin family protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cullin-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RING-box protein 1A
    Names
    SCF ubiquitin ligase Rbx1 component
    ring finger

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Aedes aegypti Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference AaegL5.0 Primary Assembly

    Genomic

    1. NC_035107.1 Reference AaegL5.0 Primary Assembly

      Range
      118834052..118849786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021846052.1 → XP_021701744.1  RING-box protein 1A isoform X1

      UniProtKB/TrEMBL
      A0A6I8T7B7
      Conserved Domains (1) summary
      cd16485
      Location:62 → 123
      mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins

    2. XM_001649547.2 → XP_001649597.1  RING-box protein 1A isoform X2

      See identical proteins and their annotated locations for XP_001649597.1

      UniProtKB/TrEMBL
      Q0IFL8, Q1HQX8
      Conserved Domains (1) summary
      cd16485
      Location:41 → 102
      mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials