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    MIER1 MIER1 transcriptional regulator [ Bos taurus (domestic cattle) ]

    Gene ID: 538742, updated on 10-Oct-2024

    Summary

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    Official Symbol
    MIER1provided by VGNC
    Official Full Name
    MIER1 transcriptional regulatorprovided by VGNC
    Primary source
    VGNC:VGNC:31469
    See related
    BGD:BT18646; Ensembl:ENSBTAG00000005443
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MIER1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (78335914..78408805, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene chromosome 3 C1orf141 homolog Neighboring gene solute carrier family 35 member D1 Neighboring gene dynein axonemal intermediate chain 4 Neighboring gene translocon-associated protein subunit alpha-like Neighboring gene small nucleolar RNA SNORA70

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mesoderm induction early response protein 1
    Names
    mesoderm induction early response 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076913.1 → NP_001070381.1  mesoderm induction early response protein 1

      See identical proteins and their annotated locations for NP_001070381.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123513
      UniProtKB/TrEMBL
      A0A3S5ZPQ7, F1N4Z3, Q08DY2
      Related
      ENSBTAP00000082701.1, ENSBTAT00000125094.1
      Conserved Domains (3) summary
      smart00717
      Location:286 → 331
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:286 → 330
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:180 → 229
      ELM2; ELM2 domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      78335914..78408805 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005204465.5 → XP_005204522.4  mesoderm induction early response protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A3S5ZPQ7
      Related
      ENSBTAP00000096541.1, ENSBTAT00000133453.1
      Conserved Domains (2) summary
      cd11661
      Location:339 → 383
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:233 → 282
      ELM2; ELM2 domain

    2. XM_005204463.5 → XP_005204520.4  mesoderm induction early response protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A3S5ZPQ7
      Conserved Domains (2) summary
      cd11661
      Location:376 → 420
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:270 → 319
      ELM2; ELM2 domain

    3. XM_024989592.2 → XP_024845360.2  mesoderm induction early response protein 1 isoform X4

      Related
      ENSBTAP00000065806.2, ENSBTAT00000069972.2

    4. XM_059884764.1 → XP_059740747.1  mesoderm induction early response protein 1 isoform X2

    5. XM_059884765.1 → XP_059740748.1  mesoderm induction early response protein 1 isoform X6

    6. XM_059884763.1 → XP_059740746.1  mesoderm induction early response protein 1 isoform X1

    7. XM_005204473.5 → XP_005204530.1  mesoderm induction early response protein 1 isoform X9

      See identical proteins and their annotated locations for XP_005204530.1

      UniProtKB/TrEMBL
      A0A3Q1LXD3, A0A3S5ZPQ7
      Related
      ENSBTAP00000061859.1, ENSBTAT00000082165.2
      Conserved Domains (2) summary
      cd11661
      Location:303 → 347
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:197 → 246
      ELM2; ELM2 domain

    8. XM_024989593.2 → XP_024845361.1  mesoderm induction early response protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LXD3, A0A3S5ZPQ7
      Conserved Domains (2) summary
      cd11661
      Location:303 → 347
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:197 → 246
      ELM2; ELM2 domain

    9. XM_059884767.1 → XP_059740750.1  mesoderm induction early response protein 1 isoform X8

    10. XM_005204477.4 → XP_005204534.1  mesoderm induction early response protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A3S5ZPQ7
      Related
      ENSBTAP00000094639.1, ENSBTAT00000135348.1
      Conserved Domains (2) summary
      cd11661
      Location:223 → 267
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:117 → 166
      ELM2; ELM2 domain

    11. XM_024989598.2 → XP_024845366.1  mesoderm induction early response protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A3S5ZPQ7
      Conserved Domains (2) summary
      cd11661
      Location:259 → 303
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:153 → 202
      ELM2; ELM2 domain

    12. XM_005204474.4 → XP_005204531.1  mesoderm induction early response protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A3Q1MIX1, A0A3S5ZPQ7
      Related
      ENSBTAP00000071259.1, ENSBTAT00000076759.2
      Conserved Domains (2) summary
      cd11661
      Location:285 → 329
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:179 → 228
      ELM2; ELM2 domain

    13. XM_059884766.1 → XP_059740749.1  mesoderm induction early response protein 1 isoform X7

    Nucleotide Protein Strain
    Heading Accession and Version

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