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    CBO_RS07560 HD domain-containing phosphohydrolase [ Clostridium botulinum A str. ATCC 3502 ]

    Gene ID: 5185779, updated on 11-Apr-2024

    Summary

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    Gene symbol
    CBO_RS07560
    Gene description
    HD domain-containing phosphohydrolase
    Locus tag
    CBO_RS07560
    Gene type
    protein coding
    Organism
    Clostridium botulinum A str. ATCC 3502 (strain: ATCC 3502)
    Lineage
    Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
    Old locus tag
    CBO1524
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    Genomic context

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    Sequence:
    NC_009495.1 (1658182..1660380)

    NC_009495.1Genomic Context describing neighboring genes Neighboring gene C-GCAxxG-C-C family protein Neighboring gene TDT family transporter Neighboring gene four-helix bundle copper-binding protein Neighboring gene methyl-accepting chemotaxis protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009495.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence Conservation, Domain Architectures, and Phylogenetic Distribution of the HD-GYP Type c-di-GMP Phosphodiesterases. Galperin MY, et al. J Bacteriol, 2022 Apr 19. PMID 34928179, Free PMC Article
    2. Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes. Sebaihia M, et al. Genome Res, 2007 Jul. PMID 17519437, Free PMC Article
    3. The HD domain defines a new superfamily of metal-dependent phosphohydrolases. Aravind L, et al. Trends Biochem Sci, 1998 Dec. PMID 9868367

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    HD domain-containing phosphohydrolase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_009495.1 Reference assembly

      Range
      1658182..1660380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_011949077.1 HD domain-containing phosphohydrolase [Clostridium botulinum]

      See identical proteins and their annotated locations for WP_011949077.1

      UniProtKB/TrEMBL
      A0A6B4K4W7, A5I201, A7G3Q5, M1ZR08
      Conserved Domains (4) summary
      cd01949
      Location:396 → 513
      GGDEF; Diguanylate-cyclase (DGC) or GGDEF domain
      COG2206
      Location:477 → 726
      HDGYP; HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant) [Signal transduction mechanisms]
      cl00549
      Location:57 → 157
      ABC_membrane; ABC transporter transmembrane region
      cl21578
      Location:265 → 391
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    Nucleotide Protein
    Heading Accession and Version