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    SMPDL3A sphingomyelin phosphodiesterase acid like 3A [ Bos taurus (cattle) ]

    Gene ID: 505300, updated on 6-Jun-2024

    Summary

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    Official Symbol
    SMPDL3Aprovided by VGNC
    Official Full Name
    sphingomyelin phosphodiesterase acid like 3Aprovided by VGNC
    Primary source
    VGNC:VGNC:35033
    See related
    BGD:BT13453; Ensembl:ENSBTAG00000021587
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SMPDL3A in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (28453551..28472137, complement)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene triadin Neighboring gene uncharacterized LOC132346210 Neighboring gene clavesin 2 Neighboring gene uncharacterized LOC101909028 Neighboring gene fatty acid binding protein 7 Neighboring gene cAMP-dependent protein kinase inhibitor beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC126943

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingomyelin phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sphingomyelin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclic GMP-AMP phosphodiesterase SMPDL3A; acid sphingomyelinase-like phosphodiesterase 3a
    Names
    2',3'-cGAMP phosphodiesterase SMPDL3A
    ASM-like phosphodiesterase 3a
    NP_001030191.1
    XP_059745580.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035019.2 → NP_001030191.1  cyclic GMP-AMP phosphodiesterase SMPDL3A precursor

      See identical proteins and their annotated locations for NP_001030191.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102796
      UniProtKB/Swiss-Prot
      Q3ZC91
      Related
      ENSBTAP00000028765.3, ENSBTAT00000028765.3
      Conserved Domains (2) summary
      cd00842
      Location:37 → 333
      MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain
      pfam00149
      Location:73 → 294
      Metallophos; Calcineurin-like phosphoesterase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      28453551..28472137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059889597.1 → XP_059745580.1  acid sphingomyelinase-like phosphodiesterase 3a isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ZC91.1 GenPept UniProtKB/Swiss-Prot:Q3ZC91

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials