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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_009447.1 RefSeqGene
- Range
-
4990..26512
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001363711.2 → NP_001350640.1 dual oxidase 2 isoform 2 precursor
Status: REVIEWED
- Source sequence(s)
-
AC091117
- Consensus CDS
-
CCDS86454.1
- UniProtKB/TrEMBL
-
X6RAN8
- Related
- ENSP00000373691.7, ENST00000389039.11
- Conserved Domains (6) summary
-
- cd06186
Location:1274 → 1548
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- cd09820
Location:38 → 594
- dual_peroxidase_like; Dual oxidase and related animal heme peroxidases
- cd00051
Location:824 → 885
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- pfam01794
Location:1088 → 1223
- Ferric_reduct; Ferric reductase like transmembrane component
- pfam13499
Location:857 → 929
- EF-hand_7; EF-hand domain pair
- cl25352
Location:764 → 858
- EFh_PEF; The penta-EF hand (PEF) family
-
NM_014080.5 → NP_054799.4 dual oxidase 2 isoform 1 precursor
See identical proteins and their annotated locations for NP_054799.4
Status: REVIEWED
- Source sequence(s)
-
AC091117, AF230496, BI045475
- Consensus CDS
-
CCDS10117.1
- UniProtKB/Swiss-Prot
- A8MQ13, D2XI64, Q9NR02, Q9NRD8, Q9UHF9
- Related
- ENSP00000475084.1, ENST00000603300.1
- Conserved Domains (6) summary
-
- cd06186
Location:1274 → 1548
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- cd09820
Location:38 → 594
- dual_peroxidase_like; Dual oxidase and related animal heme peroxidases
- cd00051
Location:824 → 885
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- pfam01794
Location:1088 → 1223
- Ferric_reduct; Ferric reductase like transmembrane component
- pfam03098
Location:36 → 547
- An_peroxidase; Animal haem peroxidase
- pfam13499
Location:824 → 884
- EF-hand_7; EF-hand domain pair
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000015.10 Reference GRCh38.p14 Primary Assembly
- Range
-
45092650..45114172 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060939.1 Alternate T2T-CHM13v2.0
- Range
-
42900666..42922193 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)