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    Cfap68 cilia and flagella associated protein 68 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500995, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Cfap68provided by RGD
    Official Full Name
    cilia and flagella associated protein 68provided by RGD
    Primary source
    RGD:1564937
    See related
    EnsemblRapid:ENSRNOG00000030962 AllianceGenome:RGD:1564937
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    C8h11orf1; RGD1564937
    Summary
    Predicted to be involved in flagellated sperm motility. Predicted to be located in axoneme and nucleoplasm. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. Orthologous to human CFAP68 (cilia and flagella associated protein 68). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Restricted expression toward (RPKM 123.9) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cfap68 in Genome Data Viewer
    Location:
    8q23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (60004034..60009782, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (51107663..51113192, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (55169413..55194692, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene heat shock protein family B (small) member 2 Neighboring gene crystallin, alpha B Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene 2 Neighboring gene ferredoxin-fold anticodon binding domain containing 1 Neighboring gene ALG9, alpha-1,2-mannosyltransferase Neighboring gene uncharacterized LOC134480165 Neighboring gene 60S ribosomal protein L27a-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in flagellated sperm motility IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axonemal A tubule inner sheath ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axoneme ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cilium ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in sperm flagellum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cilia- and flagella-associated protein 68
    Names
    UPF0686 protein C11orf1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134636.2 → NP_001128108.1  cilia- and flagella-associated protein 68

      See identical proteins and their annotated locations for NP_001128108.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6J4G0, D3ZGF3
      Related
      ENSRNOP00000062225.1, ENSRNOT00000068366.4
      Conserved Domains (1) summary
      pfam06608
      Location:26 → 165
      DUF1143; Protein of unknown function (DUF1143)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      60004034..60009782 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081955.2 → XP_038937883.1  cilia- and flagella-associated protein 68 isoform X2

      UniProtKB/TrEMBL
      A6J4F9
      Related
      ENSRNOP00000088722.2, ENSRNOT00000115569.2
      Conserved Domains (1) summary
      pfam06608
      Location:1 → 148
      DUF1143; Protein of unknown function (DUF1143)

    2. XM_039081954.2 → XP_038937882.1  cilia- and flagella-associated protein 68 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AAB0
      Conserved Domains (1) summary
      pfam06608
      Location:15 → 148
      DUF1143; Protein of unknown function (DUF1143)
    Nucleotide Protein Strain
    Heading Accession and Version

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