U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Tpi1l1 triosephosphate isomerase 1 like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500959, updated on 4-Jan-2025

    Summary

    Official Symbol
    Tpi1l1provided by RGD
    Official Full Name
    triosephosphate isomerase 1 like 1provided by RGD
    Primary source
    RGD:1560534
    See related
    EnsemblRapid:ENSRNOG00000055222 AllianceGenome:RGD:1560534
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable methylglyoxal synthase activity and triose-phosphate isomerase activity. Predicted to be involved in gluconeogenesis and glycolytic process. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and triosephosphate isomerase deficiency. Orthologous to human TPI1 (triosephosphate isomerase 1). [provided by Alliance of Genome Resources, Jan 2025]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tpi1l1 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (31923596..31931244, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (23647760..23654967, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (26341789..26342573, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene HERPUD family member 2 Neighboring gene charged multivesicular body protein 5, pseudogene 2 Neighboring gene uncharacterized LOC120094096 Neighboring gene uncharacterized LOC108351664 Neighboring gene septin 7 Neighboring gene ribosomal protein S6, pseudogene 5

    Genomic regions, transcripts, and products

    General gene information

    Clone Names

    • AC094212.1

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables methylglyoxal synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables triose-phosphate isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    triosephosphate isomerase 1 like 1
    NP_001028244.1
    XP_038937855.1
    XP_063122032.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033072.1NP_001028244.1  triosephosphate isomerase 1 like 1

      See identical proteins and their annotated locations for NP_001028244.1

      Status: PROVISIONAL

      Source sequence(s)
      AY461585
      UniProtKB/TrEMBL
      A0A8L2R053, Q6SA19
      Related
      ENSRNOP00000105930.1, ENSRNOT00000149546.1
      Conserved Domains (1) summary
      PTZ00333
      Location:2247
      PTZ00333; triosephosphate isomerase; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      31923596..31931244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081927.2XP_038937855.1  triosephosphate isomerase 1 like 1 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JWU1, A0A8L2R053
      Conserved Domains (1) summary
      PTZ00333
      Location:8251
      PTZ00333; triosephosphate isomerase; Provisional
    2. XM_063265962.1XP_063122032.1  triosephosphate isomerase 1 like 1 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JWU1, A0A8L2R053