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    Itpripl1 ITPRIP like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499885, updated on 14-Nov-2024

    Summary

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    Official Symbol
    Itpripl1provided by RGD
    Official Full Name
    ITPRIP like 1provided by RGD
    Primary source
    RGD:1564158
    See related
    EnsemblRapid:ENSRNOG00000012151 AllianceGenome:RGD:1564158
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in membrane. Orthologous to human ITPRIPL1 (ITPRIP like 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 61.0), Thymus (RPKM 45.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Itpripl1 in Genome Data Viewer
    Location:
    3q36
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (134858316..134861241, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (114403123..114407917, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (119616473..119619865, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene biliverdin reductase A Neighboring gene uncharacterized LOC134486146 Neighboring gene non-SMC condensin I complex, subunit H Neighboring gene small nuclear ribonucleoprotein U5 subunit 200 Neighboring gene cytosolic iron-sulfur assembly component 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables receptor ligand activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of T cell receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    inositol 1,4,5-trisphosphate receptor-interacting protein-like 1
    Names
    inositol 1,4,5-triphosphate receptor-interacting protein-like 1
    inositol 1,4,5-trisphosphate receptor interacting protein-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025043.1 → NP_001020214.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 precursor

      See identical proteins and their annotated locations for NP_001020214.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082013
      UniProtKB/Swiss-Prot
      Q66H52
      Related
      ENSRNOP00000079259.1, ENSRNOT00000110996.2
      Conserved Domains (1) summary
      pfam03281
      Location:287 → 514
      Mab-21; Mab-21 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      134858316..134861241 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105692.2 → XP_038961620.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A8L2Q7M6
      Conserved Domains (1) summary
      pfam03281
      Location:303 → 527
      Mab-21; Mab-21 protein

    2. XM_006234927.5 → XP_006234989.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform X1

      See identical proteins and their annotated locations for XP_006234989.1

      UniProtKB/TrEMBL
      A6HQ01
      Related
      ENSRNOP00000099379.1, ENSRNOT00000154461.1
      Conserved Domains (1) summary
      pfam03281
      Location:339 → 566
      Mab-21; Mab-21 protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66H52.1 GenPept UniProtKB/Swiss-Prot:Q66H52

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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